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Volumn 12, Issue 11, 2006, Pages 714-720

Is IGnRH-III the most potent GnRH analog containing only natural amino acids that specifically inhibits the growth of human breast cancer cells?

Author keywords

Breast cancer; IGnRH III; Inhibition of growth; Peptide library

Indexed keywords

ANTINEOPLASTIC AGENT; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLMETHIONYLGLUTAMYLPROLYLGLYCYLAMIDE; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLMETHIONYLLYSYLPROLYLGLYCYLAMIDE; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLMETHIONYLMETHIONYLPROLYLGLYCYLAMIDE; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLTRYPTOPHANYLGLUTAMYLPROLYLGLYCYLAMIDE; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLTRYPTOPHANYLLYSYLPROLYLGLYCYLAMIDE; GLUTAMYLHISTIDYLTRYPTOPHANYLSERYLTYROSYLTRYPTOPHANYLTRYPTOPHANYLMETHIONYLPROLYLGLYCYLAMIDE; GONADORELIN DERIVATIVE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; FOLLICLE STIMULATING HORMONE-RELEASING FACTOR; FOLLITROPIN RELEASING FACTOR; GONADORELIN; OLIGOPEPTIDE; PEPTIDE; PEPTIDE LIBRARY; PYROGLUTAMIC ACID;

EID: 33750701113     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.783     Document Type: Article
Times cited : (14)

References (32)
  • 1
    • 0029094429 scopus 로고
    • GnRH analog administration in patients with polycystic ovarian disease
    • Meden-Vrtovec H. GnRH analog administration in patients with polycystic ovarian disease. Int. J. Gynaecol. Obstet. 1995; 50: 179-183.
    • (1995) Int. J. Gynaecol. Obstet. , vol.50 , pp. 179-183
    • Meden-Vrtovec, H.1
  • 2
    • 13344270407 scopus 로고    scopus 로고
    • Effects of a long-acting gonadotropin-releasing hormone analog on the pituitary-ovarian-adrenal axis in women with severe hirsutism
    • Castelo-Branco C, Martinez de Osaba MJ, Martinez S, Fortuny A. Effects of a long-acting gonadotropin-releasing hormone analog on the pituitary-ovarian-adrenal axis in women with severe hirsutism. Metabolism 1996; 45: 24-27.
    • (1996) Metabolism , vol.45 , pp. 24-27
    • Castelo-Branco, C.1    Martinez de Osaba, M.J.2    Martinez, S.3    Fortuny, A.4
  • 3
    • 0033926142 scopus 로고    scopus 로고
    • The role of gonadotropins in follicular development and their use in ovulation induction protocols for assisted reproduction
    • Zafeiriou S, Loutradis D, Michalas S. The role of gonadotropins in follicular development and their use in ovulation induction protocols for assisted reproduction. Eur. J. Contracept. Reprod. Health Care. 2000; 5: 157-167.
    • (2000) Eur. J. Contracept. Reprod. Health Care. , vol.5 , pp. 157-167
    • Zafeiriou, S.1    Loutradis, D.2    Michalas, S.3
  • 4
    • 0023850131 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) agonists
    • Dutta AN. Luteinizing hormone-releasing hormone (LHRH) agonists. Drugs Future 1988; 13: 43-57.
    • (1988) Drugs Future , vol.13 , pp. 43-57
    • Dutta, A.N.1
  • 5
    • 0032739426 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone analogs: Their impact on the control of tumorigenesis
    • Schally AV. Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis. Peptides 1999; 20: 1247-1262.
    • (1999) Peptides , vol.20 , pp. 1247-1262
    • Schally, A.V.1
  • 7
    • 0023708204 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH) antagonists
    • Dutta AN. Luteinizing hormone-releasing hormone (LHRH) antagonists. Drugs Future 1988; 13: 761-787.
    • (1988) Drugs Future , vol.13 , pp. 761-787
    • Dutta, A.N.1
  • 8
    • 0021857861 scopus 로고
    • Reproductive/endocrine and anaphylactoid properties of an LHRH-antagonist, ORF 18260 [Ac-DNAL1(2),4FDPhe2,D-Trp3,D-Arg6]-GnRH
    • Hahn DW, McGuire JL, Vale WW, Rivier J. Reproductive/endocrine and anaphylactoid properties of an LHRH-antagonist, ORF 18260 [Ac-DNAL1(2),4FDPhe2,D-Trp3,D-Arg6]-GnRH. Life Sci. 1985; 37: 505-514.
    • (1985) Life Sci. , vol.37 , pp. 505-514
    • Hahn, D.W.1    McGuire, J.L.2    Vale, W.W.3    Rivier, J.4
  • 10
    • 0027465167 scopus 로고
    • Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain
    • Sower SA, Chiang Y-C, Lovas S, Conlon JM. Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain. Endocrinol. 1993; 132: 1125-1131.
    • (1993) Endocrinol. , vol.132 , pp. 1125-1131
    • Sower, S.A.1    Chiang, Y.-C.2    Lovas, S.3    Conlon, J.M.4
  • 12
    • 0036668076 scopus 로고    scopus 로고
    • Lamprey gonadotropin hormone-releasing hormone-III has no selective follicle-stimulating hormone-releasing effect in rats
    • Kovacs M, Seprodi J, Koppan M, Horvath JE, Vincze B, Teplan I, Flerko B. Lamprey gonadotropin hormone-releasing hormone-III has no selective follicle-stimulating hormone-releasing effect in rats. J Neuroendocrinol. 2002; 14: 647-655.
    • (2002) J Neuroendocrinol. , vol.14 , pp. 647-655
    • Kovacs, M.1    Seprodi, J.2    Koppan, M.3    Horvath, J.E.4    Vincze, B.5    Teplan, I.6    Flerko, B.7
  • 14
    • 0033735761 scopus 로고    scopus 로고
    • Influence on antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues
    • Kalnay A, Palyi I, Vincze B, Mihalik R, Mezo I, Palo J, Seprodi J, Lovas S, Murphy RF. Influence on antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues. Cell Prolif. 2000; 33: 275-285.
    • (2000) Cell Prolif. , vol.33 , pp. 275-285
    • Kalnay, A.1    Palyi, I.2    Vincze, B.3    Mihalik, R.4    Mezo, I.5    Palo, J.6    Seprodi, J.7    Lovas, S.8    Murphy, R.F.9
  • 15
    • 0037012226 scopus 로고    scopus 로고
    • Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates
    • Dubois EA, Zandbergen MA, Peute J, Goos HJT. Evolutionary development of three gonadotropin-releasing hormone (GnRH) systems in vertebrates. Brain Res. Bull. 2002; 57: 413-418.
    • (2002) Brain Res. Bull. , vol.57 , pp. 413-418
    • Dubois, E.A.1    Zandbergen, M.A.2    Peute, J.3    Goos, H.J.T.4
  • 16
    • 0344851635 scopus 로고    scopus 로고
    • Evolution of the role of GnRH in animal (Metazoan) biology
    • Gorbman A, Sower SA. Evolution of the role of GnRH in animal (Metazoan) biology. Gen. Comp. Endocrinol. 2002; 134: 207-213.
    • (2002) Gen. Comp. Endocrinol. , vol.134 , pp. 207-213
    • Gorbman, A.1    Sower, S.A.2
  • 17
    • 0347320615 scopus 로고    scopus 로고
    • The biology of gonadotropin-releasing hormone: Role in the control of tumor growth and progression in humans
    • Limonta P, Moretti RM, Montagnani-Marelli M, Motta M. The biology of gonadotropin-releasing hormone: role in the control of tumor growth and progression in humans. Front. Neuroendocrinol. 2003; 24: 279-295.
    • (2003) Front. Neuroendocrinol. , vol.24 , pp. 279-295
    • Limonta, P.1    Moretti, R.M.2    Montagnani-Marelli, M.3    Motta, M.4
  • 18
    • 0028861258 scopus 로고
    • Inhibition of growth of human ovarian cancer in nude mice by luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75)
    • Manetta A, Gamboa-Vujicic G, Paredes P, Emma D, Liao S, Leong L, Asch B, Schally A. Inhibition of growth of human ovarian cancer in nude mice by luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75). Fertil Steril. 1995; 63: 282-287.
    • (1995) Fertil Steril. , vol.63 , pp. 282-287
    • Manetta, A.1    Gamboa-Vujicic, G.2    Paredes, P.3    Emma, D.4    Liao, S.5    Leong, L.6    Asch, B.7    Schally, A.8
  • 19
    • 0033842808 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonist triptorelin and antagonist cetrorelix inhibit EGF-induced c-fos expression in human gynecological cancers
    • Grundker C, Volker P, Schulz KD, Emons G. Luteinizing hormone-releasing hormone agonist triptorelin and antagonist cetrorelix inhibit EGF-induced c-fos expression in human gynecological cancers. Gynecol. Oncol. 2000; 78: 194-202.
    • (2000) Gynecol. Oncol. , vol.78 , pp. 194-202
    • Grundker, C.1    Volker, P.2    Schulz, K.D.3    Emons, G.4
  • 21
    • 0026545546 scopus 로고
    • Direct effects of luteinizing hormone-releasing hormone agonists and antagonists on MCF-7 mammary cancer cells
    • Segal-Abramson T, Kitroser H, Levy J, Schaly AV, Sharoni Y. Direct effects of luteinizing hormone-releasing hormone agonists and antagonists on MCF-7 mammary cancer cells. Proc. Natl. Acad. Sci. U.S.A. 1992; 15: 2336-2339.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.15 , pp. 2336-2339
    • Segal-Abramson, T.1    Kitroser, H.2    Levy, J.3    Schaly, A.V.4    Sharoni, Y.5
  • 22
    • 12344272910 scopus 로고    scopus 로고
    • Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth
    • Heredi-Szabo K, Lubke J, Toth G, Murphy RF, Lovas S. Importance of the central region of lamprey gonadotropin-releasing hormone III in the inhibition of breast cancer cell growth. Peptides 2005; 26: 419-422.
    • (2005) Peptides , vol.26 , pp. 419-422
    • Heredi-Szabo, K.1    Lubke, J.2    Toth, G.3    Murphy, R.F.4    Lovas, S.5
  • 23
    • 0344851635 scopus 로고    scopus 로고
    • Evolution of the role of GnRH in animal (Metazoan) biology
    • Gorbman A, Sower SA. Evolution of the role of GnRH in animal (Metazoan) biology. Gen. Comp. Endocrinol. 2003; 134: 207-213.
    • (2003) Gen. Comp. Endocrinol. , vol.134 , pp. 207-213
    • Gorbman, A.1    Sower, S.A.2
  • 24
    • 0034747357 scopus 로고    scopus 로고
    • Role of aspartate 7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation
    • Fromme BJ, Katz AA, Roeske RW, Millar RP, Flanagan CA. Role of aspartate 7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation. Mol. Pharmacol. 2001; 60: 1280-1287.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1280-1287
    • Fromme, B.J.1    Katz, A.A.2    Roeske, R.W.3    Millar, R.P.4    Flanagan, C.A.5
  • 25
    • 0242289982 scopus 로고    scopus 로고
    • GnRH-II analogs for selective activation and inhibition of non-mammalian and type-II mammalian GnRH receptors
    • Maiti K, Li JH, Wang AF, Acharjee S, Kim WP, Im WB, Kwon HB, Seong JY. GnRH-II analogs for selective activation and inhibition of non-mammalian and type-II mammalian GnRH receptors. Mol. Cells. 2003; 16: 173-179.
    • (2003) Mol. Cells , vol.16 , pp. 173-179
    • Maiti, K.1    Li, J.H.2    Wang, A.F.3    Acharjee, S.4    Kim, W.P.5    Im, W.B.6    Kwon, H.B.7    Seong, J.Y.8
  • 26
    • 0242266467 scopus 로고    scopus 로고
    • Preferential ligand selectivity of the monkey type-II gonadotropin-releasing hormone (GnRH) receptor for GnRH-2 and its analogs
    • Wang AF, Li JH, Maiti K, Kim WP, Kang HM, Seong JY, Kwon HB. Preferential ligand selectivity of the monkey type-II gonadotropin-releasing hormone (GnRH) receptor for GnRH-2 and its analogs. Mol. Cell. Endocrinol. 2003; 209: 33-42.
    • (2003) Mol. Cell. Endocrinol. , vol.209 , pp. 33-42
    • Wang, A.F.1    Li, J.H.2    Maiti, K.3    Kim, W.P.4    Kang, H.M.5    Seong, J.Y.6    Kwon, H.B.7
  • 28
    • 0027134802 scopus 로고
    • High affinity binding and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell lines
    • Emons G, Schroder B, Ortmann O, Westphalen S, Schulz K-D, Schally AV. High affinity binding and direct antiproliferative effects of luteinizing hormone-releasing hormone analogs in human endometrial cancer cell lines. J. Clin. Endocrinol. Metab. 1993; 77: 1458-1464.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 1458-1464
    • Emons, G.1    Schroder, B.2    Ortmann, O.3    Westphalen, S.4    Schulz, K.-D.5    Schally, A.V.6
  • 29
    • 4344633012 scopus 로고    scopus 로고
    • Antiproliferative effects of the GnRH antagonist cetrorelix and of GnRH-II on human endometrial and ovarian cancer cells are not mediated through the GnRH type I receptor
    • Grundker C, Schlotawa L, Viereck V, Eicke N, Horst A, Kairies B, Emons G. Antiproliferative effects of the GnRH antagonist cetrorelix and of GnRH-II on human endometrial and ovarian cancer cells are not mediated through the GnRH type I receptor. Eur. J. Endocrinol. 2004; 151: 141-149.
    • (2004) Eur. J. Endocrinol. , vol.151 , pp. 141-149
    • Grundker, C.1    Schlotawa, L.2    Viereck, V.3    Eicke, N.4    Horst, A.5    Kairies, B.6    Emons, G.7
  • 30
    • 0035020249 scopus 로고    scopus 로고
    • Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase
    • Grundker C, Volker P, Emons G. Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase. Endocrinol. 2001; 142: 2369-2380.
    • (2001) Endocrinol. , vol.142 , pp. 2369-2380
    • Grundker, C.1    Volker, P.2    Emons, G.3
  • 32
    • 0036965115 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation
    • Grundker C, Gunthert AR, Millar RP, Emons G. Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation. J. Clin. Endocrinol. Metab. 2002; 87: 1427-1430.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1427-1430
    • Grundker, C.1    Gunthert, A.R.2    Millar, R.P.3    Emons, G.4


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