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Volumn 23, Issue 11, 2006, Pages 2681-2688

Bioavailability of seocalcitol IV: Evaluation of lymphatic transport in conscious rats

Author keywords

Long chain triglycerides; Lymphatic transport; Propylene glycol; Seocalcitol

Indexed keywords

LONG CHAIN TRIACYLGLYCEROL; PROPYLENE GLYCOL; SEOCALCITOL; TRITIUM;

EID: 33750620037     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9109-z     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 0343051915 scopus 로고    scopus 로고
    • Uptake of drugs into the intestinal lymphatics after oral administration
    • C. J. Porter and W. N. Charman. Uptake of drugs into the intestinal lymphatics after oral administration. Adv. Drug Deliv. Rev. 25:71-89 (1997).
    • (1997) Adv. Drug Deliv. Rev. , vol.25 , pp. 71-89
    • Porter, C.J.1    Charman, W.N.2
  • 2
    • 0034601204 scopus 로고    scopus 로고
    • Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs
    • T. Gershanik and S. Benita. Self-dispersing lipid formulations for improving oral absorption of lipophilic drugs. Eur. J. Pharm. Biopharm. 50:179-188 (2000).
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , pp. 179-188
    • Gershanik, T.1    Benita, S.2
  • 3
    • 0342617694 scopus 로고    scopus 로고
    • Lipid-based vehicles for the oral delivery of poorly water soluble drugs
    • A. J. Humberstone and W. N. Charman. Lipid-based vehicles for the oral delivery of poorly water soluble drugs. Adv. Drug Deliv. Rev. 25:103-128 (1997).
    • (1997) Adv. Drug Deliv. Rev. , vol.25 , pp. 103-128
    • Humberstone, A.J.1    Charman, W.N.2
  • 4
    • 0035984949 scopus 로고    scopus 로고
    • Lipid-based formulations for intestinal lymphatic delivery
    • C. M. O'Driscoll. Lipid-based formulations for intestinal lymphatic delivery. Eur. J. Pharm. Sci. 15:405-415 (2002).
    • (2002) Eur. J. Pharm. Sci. , vol.15 , pp. 405-415
    • O'Driscoll, C.M.1
  • 5
    • 0033991176 scopus 로고    scopus 로고
    • A proposed model for the assembly of chylomicrons
    • M. M. Hussain. A proposed model for the assembly of chylomicrons. Atherosclerosis 148:1-15 (2000).
    • (2000) Atherosclerosis , vol.148 , pp. 1-15
    • Hussain, M.M.1
  • 6
    • 0023276505 scopus 로고
    • Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules
    • W. N. Charman and V. J. Stella. Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules. Int. J. Pharm. 34:175-178 (1986).
    • (1986) Int. J. Pharm. , vol.34 , pp. 175-178
    • Charman, W.N.1    Stella, V.J.2
  • 7
    • 0028234686 scopus 로고
    • Targeted lymphatic transport and modified systemic distribution of CI-976, a lipophilic lipid-regulator drug, via a formulation approach
    • D. J. Hauss, S. C. Mehta, and G. W. Radebaugh. Targeted lymphatic transport and modified systemic distribution of CI-976, a lipophilic lipid-regulator drug, via a formulation approach. Int. J. Pharm. 108:85-93 (1994).
    • (1994) Int. J. Pharm. , vol.108 , pp. 85-93
    • Hauss, D.J.1    Mehta, S.C.2    Radebaugh, G.W.3
  • 8
    • 0026809853 scopus 로고
    • Systemic bioavailability of penclomedine (NSC-338720) from oil-in-water emulsions administered intraduodenally to rats
    • R. A. Myers and V. J. Stella. Systemic bioavailability of penclomedine (NSC-338720) from oil-in-water emulsions administered intraduodenally to rats. Int. J. Pharm. 78:217-226 (1992).
    • (1992) Int. J. Pharm. , vol.78 , pp. 217-226
    • Myers, R.A.1    Stella, V.J.2
  • 9
    • 1442324408 scopus 로고    scopus 로고
    • Successful in silico predicting of intestinal lymphatic transfer
    • R. Holm and J. Hoest. Successful in silico predicting of intestinal lymphatic transfer. Int. J. Pharm. 272:189-193 (2004).
    • (2004) Int. J. Pharm. , vol.272 , pp. 189-193
    • Holm, R.1    Hoest, J.2
  • 10
    • 0027488715 scopus 로고
    • EB 1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells
    • I. S. Mathiasen, K. W. Colston, and L. Binderup. EB 1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells. J. Steroid Biochem. Mol. Biol. 46:365-371 (1993).
    • (1993) J. Steroid Biochem. Mol. Biol. , vol.46 , pp. 365-371
    • Mathiasen, I.S.1    Colston, K.W.2    Binderup, L.3
  • 11
    • 14144249452 scopus 로고    scopus 로고
    • Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs
    • A. Dahan and A. Hoffman. Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs. Eur. J. Pharm. Sci. 24:381-388 (2005).
    • (2005) Eur. J. Pharm. Sci. , vol.24 , pp. 381-388
    • Dahan, A.1    Hoffman, A.2
  • 12
    • 0028937137 scopus 로고
    • Mechanism of promotion of lymphatic drug absorption by milk fat globule membrane
    • H. Liu, I. Adachi, I. Horikoshi, and M. Ueno. Mechanism of promotion of lymphatic drug absorption by milk fat globule membrane. Int. J. Pharm. 118:55-64 (1995).
    • (1995) Int. J. Pharm. , vol.118 , pp. 55-64
    • Liu, H.1    Adachi, I.2    Horikoshi, I.3    Ueno, M.4
  • 13
    • 0019474331 scopus 로고
    • Intestinal absorption of vitamin D sterols: Differential absorption into lymph and portal blood in the rat
    • M. Maislos, J. Silver, and M. Fainaru. Intestinal absorption of vitamin D sterols: differential absorption into lymph and portal blood in the rat. Gastroenterology 80:1528-1534 (1981).
    • (1981) Gastroenterology , vol.80 , pp. 1528-1534
    • Maislos, M.1    Silver, J.2    Fainaru, M.3
  • 14
    • 50349115008 scopus 로고
    • Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat
    • J. L. Bollman, J. C. Cain, and J. H. Grindlay. Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat. J. Lab. Clin. Med. 33:1349-1352 (1948).
    • (1948) J. Lab. Clin. Med. , vol.33 , pp. 1349-1352
    • Bollman, J.L.1    Cain, J.C.2    Grindlay, J.H.3
  • 15
    • 25444464372 scopus 로고    scopus 로고
    • Bioavailability of seocalcitol. I. Relating solubility in biorelevant media with oral bioavailability in rats - Effect of medium and long chain triglycerides
    • M. Grove, G. P. Pedersen, J. L. Nielsen, and A. Mullertz. Bioavailability of seocalcitol. I. Relating solubility in biorelevant media with oral bioavailability in rats - effect of medium and long chain triglycerides. J. Pharm. Sci. 94:1830-1838 (2005).
    • (2005) J. Pharm. Sci. , vol.94 , pp. 1830-1838
    • Grove, M.1    Pedersen, G.P.2    Nielsen, J.L.3    Mullertz, A.4
  • 16
    • 0034854134 scopus 로고    scopus 로고
    • Comparison of the lymphatic transport of halofantrine administered in disperse systems containing three different unsaturated fatty acids
    • R. Holm, A. Mullertz, G. P. Pedersen, and H. G. Kristensen. Comparison of the lymphatic transport of halofantrine administered in disperse systems containing three different unsaturated fatty acids. Pharm. Res. 18:1299-1304 (2001).
    • (2001) Pharm. Res. , vol.18 , pp. 1299-1304
    • Holm, R.1    Mullertz, A.2    Pedersen, G.P.3    Kristensen, H.G.4
  • 17
    • 0033800498 scopus 로고    scopus 로고
    • VolSurf: A new tool for the pharmacokinetic optimization of lead compounds
    • G. Cruciani, M. Pastor, and W. Guba. VolSurf: a new tool for the pharmacokinetic optimization of lead compounds. Eur. J. Pharm. Sci. 11(Suppl 2):S29-S39 (2000).
    • (2000) Eur. J. Pharm. Sci. , vol.11 , Issue.SUPPL. 2
    • Cruciani, G.1    Pastor, M.2    Guba, W.3
  • 18
    • 0034625096 scopus 로고    scopus 로고
    • Molecular fields in quantitative structure-permeation relationships: The VolSurf approach
    • G. Cruciani, P. Crivori, P. A. Carrupt, and B. Testa. Molecular fields in quantitative structure-permeation relationships: the VolSurf approach. J. Mol. Struct. Theochem 503:17-30 (2000).
    • (2000) J. Mol. Struct. Theochem , vol.503 , pp. 17-30
    • Cruciani, G.1    Crivori, P.2    Carrupt, P.A.3    Testa, B.4
  • 19
    • 0034039812 scopus 로고    scopus 로고
    • Lymphatic transport in rats of several dietary fats differing in fatty acid profile and triacylglycerol structure
    • T. Porsgaard and C. E. Hoy. Lymphatic transport in rats of several dietary fats differing in fatty acid profile and triacylglycerol structure. J. Nutr. 130:1619-1624 (2000).
    • (2000) J. Nutr. , vol.130 , pp. 1619-1624
    • Porsgaard, T.1    Hoy, C.E.2
  • 20
    • 0030003723 scopus 로고    scopus 로고
    • Lymphatic transport of halofantrine in the conscious rat when administered as either the free base or the hydrochloride salt: Effect of lipid class and lipid vehicle dispersion
    • C. J. Porter, S. A. Charman, A. J. Humberstone, and W. N. Charman. Lymphatic transport of halofantrine in the conscious rat when administered as either the free base or the hydrochloride salt: effect of lipid class and lipid vehicle dispersion. J. Pharm. Sci. 85:357-361 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 357-361
    • Porter, C.J.1    Charman, S.A.2    Humberstone, A.J.3    Charman, W.N.4
  • 21
    • 0033818432 scopus 로고    scopus 로고
    • Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats
    • 1084
    • S. M. Caliph, W. N. Charman, and C. J. Porter. Effect of short-, medium-, and long-chain fatty acid-based vehicles on the absolute oral bioavailability and intestinal lymphatic transport of halofantrine and assessment of mass balance in lymph-cannulated and non-cannulated rats. J. Pharm. Sci.89:1073-1084 1084(2000).
    • (2000) J. Pharm. Sci. , vol.89 , pp. 1073-1084
    • Caliph, S.M.1    Charman, W.N.2    Porter, C.J.3
  • 22
    • 0036744709 scopus 로고    scopus 로고
    • Structured triglyceride vehicles for oral delivery of halofantrine: Examination of intestinal lymphatic transport and bioavailability in conscious rats
    • R. Holm, C. J. Porter, A. Mullertz, H. G. Kristensen, and W. N. Charman. Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats. Pharm. Res. 19:1354-1361 (2002).
    • (2002) Pharm. Res. , vol.19 , pp. 1354-1361
    • Holm, R.1    Porter, C.J.2    Mullertz, A.3    Kristensen, H.G.4    Charman, W.N.5
  • 23
    • 0034783589 scopus 로고    scopus 로고
    • Comparison of total oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats
    • R. Holm, A. Mullertz, E. Christensen, C. E. Hoy, and H. G. Kristensen. Comparison of total oral bioavailability and the lymphatic transport of halofantrine from three different unsaturated triglycerides in lymph-cannulated conscious rats. Eur. J. Pharm. Sci. 14:331-337 (2001).
    • (2001) Eur. J. Pharm. Sci. , vol.14 , pp. 331-337
    • Holm, R.1    Mullertz, A.2    Christensen, E.3    Hoy, C.E.4    Kristensen, H.G.5
  • 25
    • 0036170675 scopus 로고    scopus 로고
    • Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats
    • P. Tso, K. Ding, S. DeMichele, and Y. S. Huang. Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. J. Nutr. 132:218-221 (2002).
    • (2002) J. Nutr. , vol.132 , pp. 218-221
    • Tso, P.1    Ding, K.2    DeMichele, S.3    Huang, Y.S.4
  • 26
    • 0035172817 scopus 로고    scopus 로고
    • Comparison of the lymphatic transport of a lipophilic drug from vehicles containing alpha-tocopherol and/or triglycerides in rats
    • P. B. Nielsen, A. Mullertz, T. Norling, and H. G. Kristensen. Comparison of the lymphatic transport of a lipophilic drug from vehicles containing alpha-tocopherol and/or triglycerides in rats. J. Pharm. Pharmacol. 53:1439-1445 (2001).
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 1439-1445
    • Nielsen, P.B.1    Mullertz, A.2    Norling, T.3    Kristensen, H.G.4
  • 27
    • 0031914282 scopus 로고    scopus 로고
    • Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor
    • D. J. Hauss, S. E. Fogal, J. V. Ficorilli, C. A. Price, T. Roy, A. A. Jayaraj, and J. J. Keirns. Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J. Pharm. Sci. 87:164-169 (1998).
    • (1998) J. Pharm. Sci. , vol.87 , pp. 164-169
    • Hauss, D.J.1    Fogal, S.E.2    Ficorilli, J.V.3    Price, C.A.4    Roy, T.5    Jayaraj, A.A.6    Keirns, J.J.7
  • 28
    • 0034762181 scopus 로고    scopus 로고
    • A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine
    • S. M. Khoo, G. A. Edwards, C. J. Porter, and W. N. Charman. A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine. J. Pharm. Sci. 90:1599-1607 (2001).
    • (2001) J. Pharm. Sci. , vol.90 , pp. 1599-1607
    • Khoo, S.M.1    Edwards, G.A.2    Porter, C.J.3    Charman, W.N.4
  • 29
    • 27644453872 scopus 로고    scopus 로고
    • Uptake of lipophilic drugs by plasma derived isolated chylomicrons: Linear correlation with intestinal lymphatic bioavailability
    • P. Gershkovich and A. Hoffman. Uptake of lipophilic drugs by plasma derived isolated chylomicrons: linear correlation with intestinal lymphatic bioavailability. Eur. J. Pharm. Sci. 26:394-404 (2005).
    • (2005) Eur. J. Pharm. Sci. , vol.26 , pp. 394-404
    • Gershkovich, P.1    Hoffman, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.