Aberrant low expression level of bovine β-lactoglobulin is associated with a C to A transversion in the BLG promoter region

Journal of Dairy Science

Volumn 89, Issue 11, 2006, Pages 4414-4419

  Braunschweig, M H ^a   Leeb, T ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Expression; Genetic polymorphism; Milk protein; lactoglobulin

Indexed keywords

BOS TAURUS; BOVIDAE;

EID: 33750595938     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(06)72488-2     Document Type: Article

References (24)

1. Aschaffenburg, R., and J. Drewry. 1955. Occurrence of different β-lactoglobulins in cow's milk. Nature 176:218-219.
2. Aschaffenburg, R., and J. Drewry. 1957. Genetics of the β-lactoglobulins of cow's milk. Nature 180:376-378.
3. Braunschweig, M., C. Hagger, G. Stranzinger, and Z. Puhan. 2000. Associations between casein haplotypes and milk production traits of Swiss Brown cattle. J. Dairy Sci. 83:1387-1395.
4. Cerbulis, J., and H. M. Farrell, Jr. 1975. Composition of milks of dairy cattle. I. Protein, lactose, and fat contents and distribution of protein fraction. J. Dairy Sci. 58:817.
5. Ehrmann, S., H. Bartenschlager, and H. Geldermann. 1997. Polymorphism in the 5′-flanking region of the bovine-lactoglobulin-encoding gene and its association with 3-lactoglobulin in the milk. J. Anim. Breed. Genet. 114:49-53.
6. Farrell, H. M., Jr., R. Jimenez-Flores, G. T. Bleck, E. M. Brown, J. E. Butler, L. K. Creamer, C. L. Hicks, C. M. Hollar, K. F. Ng-Kwai-Hang, and H. E. Swaisgood. 2004. Nomenclature of the proteins of cows' milk - Sixth revision. J. Dairy Sci. 87:1641-1674.
7. Folch, J. M., P. Dovc, and J. F. Medrano. 1999. Differential expression of bovine β-lactoglobulin A and B promoter variants in transiently transfected HC11 cells. J. Dairy Res. 66:537-544.
8. Galang, C. K., W. J. Muller, G. Foos, R. G. Oshima, and C. A. Hauser. 2004. Changes in the expression of many ETS family transcription factors and of potential target genes in normal mammary tissue and tumors. J. Biol. Chem. 279:11281-11292.
9. s1-casein locus in cattle. Genet. Sel. Evol. 21:547.
10. Hansen, S. K., P. A. Baeuerle, and F. Blasi. 1994. RT purification, reconstitution, and I κ association of the c-Rel-p65 (RelA) complex, a strong activator of transcription. Mol. Cell. Biol. 14:2593-2603.
11. Hill, J. P. 1993. The relationship between β-lactoglobulin phenotypes and milk composition in New Zealand dairy cattle. J. Dairy Sci. 76:281.
12. Kim, J. S., M. Braunschweig, and Z. Puhan. 1996. Occurrence of extreme ratio of β-lactoglobulin variants A and B in Swiss Brown cattle quantified by capillary electrophoresis. Milchwissenschaft 51:435-438.
13. Kroeker, E. M., K. F. Ng-Kwai-Hang, J. F. Hayes, and J. E. Moxley. 1985. Effect of β-lactoglobulin variant and environmental factors on variation in the detailed composition of bovine milk serum proteins. J. Dairy Sci. 68:1637.
14. Kuss, A. W., J. Gogol, and H. Geldermann. 2003. Associations of a polymorphic AP-2 binding site in the 5′-flanking region of the bovine β-lactoglobulin gene with milk proteins. J. Dairy Sci. 86:2213-2218.
15. Latinkic, B. V., M. Zeremski, and L. F. Lau. 1996. Elk-1 can recruit SRF to form a ternary complex upon the serum response element. Nucleic Acids Res. 24:1345-1351.
16. Lien, S., S. Rogne, M. J. Brovold, and P. Aleström. 1990. A method for isolation of DNA from frozen (A.I.) bulls semen. J. Anim. Breed. Genet. 107:74.
17. Ling, Y., J. H. Lakey, C. E. Roberts, and A. D. Sharrocks. 1997. Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1. EMBO J. 16:2431-2440.
18. Lum, L. S., P. Dove, and J. F. Medrano. 1997. Polymorphisms of bovine β-lactoglobulin promoter and differences in the binding affinity of activator protein-2 transcription factor. J. Dairy Sci. 80:1389-1397.
19. Ng-Kwai-Hang, K. F., and S. Kim. 1996. Different amounts of β-lactoglobulin A and B in milk from heterozygous AB cows. Int. Dairy J. 6:689-695.
20. Pérez, M. D., and M. Calvo. 1995. Interaction of β-lactoglobulin with retinol and fatty acids and its role as a possible biological function for this protein: A review. J. Dairy Sci. 78:978-988.
21. Reimerdes, E. H., and H.-A. Mehrens. 1978. Die quantitative Bestimmung der genetischen Varianten von β-lactoglobulin in Milch. Milchwissenschaft 33:345-348.
22. Robitaille, G., M. Britten, J. Morisset, and D. Petitclerc. 2002. Quantitative analysis of β-lactoglobulin A and B genetic variants in milk of cows β-lactoglobulin AB throughout lactation. J. Dairy Res. 69:651-654.
23. Wagner, V. A., T. A. Schild, and H. Geldermann. 1994. DNA variants within the 5′-flanking region of milk-protein-encoding genes. II. The β-lactoglobulin-encoding gene. Theor. Appl. Genet. 89:121-126.
24. Wilkins, R. J., H. W. Davey, T. T. Wheeler, and C. A. Ford. 1995. Differential expression of β-lactoglobulin alleles A and B in dairy cattle. Pages 189-190 in Intercellular Signalling in the Mammary Gland. C. J. Wilde, M. Peaker, and C. H. Knight, ed. Plenum Press, New York, NY.