Pregnancy outcomes in a patient-heterozygous carrier of R506Q mutation of factor V (Leiden);Ishodi trudnoća u bolesnice-heterozigotne nositeljice R506Q mutacije faktora V (Leiden)

Acta Medica Croatica

Volumn 60, Issue 3, 2006, Pages 277-280

  Herman, Mislav ^a   Djelmiš, Josip ^a   Trošelj, Željko ^a   Ivanišević, Marina ^a  

^a KBC Zagreb   (Croatia)

Author keywords

Factor V (Leiden) R506Q mutation; Genetic thrombophilia; Intrauterine fetal death; Placental abruption; Preeclampsia

Indexed keywords

BLOOD CLOTTING FACTOR 5; LOW MOLECULAR WEIGHT HEPARIN; PROTEIN C; BLOOD CLOTTING FACTOR 5 LEIDEN;

ADULT; ANAMNESIS; CASE REPORT; CESAREAN SECTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FETUS DEATH; GENE MUTATION; GENETIC DISORDER; GESTATION PERIOD; HETEROZYGOTE; HUMAN; INDUCED ABORTION; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PREGNANCY OUTCOME; PROTEIN ANALYSIS; REVIEW; SOLUTIO PLACENTAE; SPONTANEOUS ABORTION; STILLBIRTH; THROMBOPHILIA; ACTIVATED PROTEIN C RESISTANCE; ARTICLE; GENETICS; NEWBORN; POINT MUTATION; PREGNANCY; PREGNANCY COMPLICATION;

ACTIVATED PROTEIN C RESISTANCE; ADULT; FACTOR V; FEMALE; HETEROZYGOTE; HUMANS; INFANT, NEWBORN; POINT MUTATION; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY OUTCOME; THROMBOPHILIA;

EID: 33750595813     PISSN: 13300164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (19)

1. Kupferminc MJ. Thrombophilia and pregnancy. Curr Pharm Des 2005; 11: 735-48.
2. Alonso A, Soto I, Urgelles MF, Corte JR, Rodriguez MJ, Pinto CR. Acquired and inherited thrombophilia in women with unexplained fetal losses. Am J Obstet Gynecol 2002; 187: 1337-42.
3. Lee R. Factor V Leiden: a clinical review. Am J Med Sci. 2001; 322: 88-102.
4. Vossen CY, Preston FE, Conard J i sur. Hereditary thrombophilia and fetal loss: a prospective follow-up study. J Thromb Haemost 2004; 2: 592-6.
5. Adelberg AM, Kuller JA Thrombophilias and recurrent miscarriage. Obstet Gynecol Surv 2002; 57: 703-9.
6. Robertson L, Wu O, Greer I. Thrombophilia and adverse pregnancy outcome. Curr Opin Obstet Gynecol 2004; 16: 453-8.
7. Kujovich JL. Thrombophilia and pregnancy complications. Am J Obstet Gynecol 2004; 191: 412-24.
8. Agorastos T, Karavida A, Lambropoulos A i sur. Factor V Leiden and prothrombin G20210A mutations in pregnancies with adverse outcome. J Matern Fetal Neonatal Med 2002; 12: 267-73.
9. Sarig G, Younis JS, Hoffman R, Lanir N, Blumenfeld Z, Brenner B. Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage. Fertil Steril 2002; 77: 342-7.
10. Kupferminc MJ, Rimon E, Ascher-Landsberg J, Lessing JB, Many A. Perinatal outcome in women with severe pregnancy complications and multiple thrombophilias. J Perinat Med 2004; 32: 225-7.
11. Spaanderman ME, Aardenburg R, Ekhart TH, van Eyndhoven HW, de Leeuw PW, Peeters LL. Pre-pregnant prediction of recurrent preeclampsia in normotensive thrombophilic formerly preeclamptic women receiving prophylactic antithrombotic medication. J Soc Gynecol Investig 2005; 12: 112-7.
12. Said J, Dekker G. Pre-eclampsia and thrombophilia. Best Pract Res Clin Obstet Gynaecol 2003; 17: 441-58.
13. Brenner B, Grabowski EF, Hellgren M i sur. Thrombophilia and pregnancy complications. Thromb Haemost 2004; 92: 678-81.
14. Djelmis J, Ivanisevic M, Kurjak A, Mayer D. Hemostatic problems before, during and after delivery. J Perinat Med 2001; 29: 241-6.
15. Cagirgan S, Donmez A, Ispahi C. Activated protein C resistance in preeclampsia. Clin Exp Obstet Gynecol 2004; 31: 59-62.
16. Benedetto C, Marozio L, Salton L, Maula V, Chieppa G, Massobrio M Factor V Leiden and factor II G20210A in preeclampsia and HELLP syndrome Acta Obstet Gynecol Scand 2002; 81: 1095-100.
17. Bozzo M, Carpani G, Leo L i sur. HELLP syndrome and factor V Leiden. Eur J Obstet Gynecol Reprod Biol 2001; 95: 55-8.
18. Prochazka M, Happach C, Marsal K, Dahlback B, Lindqvist PG. Factor V Leiden in pregnancies complicated by placental abruption. BJOG 2003; 110: 462-6.
19. Wiener-Megnagi Z, Ben-Shlomo I, Goldberg Y, Shalev E. Resistance to activated protein C and the Leiden mutation: high prevalence in patients with abruptio placentae. Am J Obstet Gynecol 1998; 179(6 Pt 1): 1565-7.