Hypertension produced by reductions in uterine perfusion in the pregnant rat: Role of interleukin 6

Hypertension

Volumn 48, Issue 4, 2006, Pages 711-716

  Gadonski, Giovani ^a   LaMarca, B Babbette D ^a   Sullivan, Elizabeth ^a   Bennett, William ^a   Chandler, Derrick ^a   Granger, Joey P ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Cytokines; Endothelin; Hypertension; Kidney

Indexed keywords

INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 6; ENDOTHELIN 1; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; GLOMERULUS FILTRATION RATE; HYPERTENSION; INTRAUTERINE PRESSURE; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY PLASMA FLOW; NONHUMAN; PLASMA RENIN ACTIVITY; PREGNANCY; PRIORITY JOURNAL; RAT; ABDOMINAL AORTA; ANIMAL; BLOOD; BLOOD FLOW; BLOOD PRESSURE; HEMODYNAMICS; KIDNEY; KIDNEY CIRCULATION; METABOLISM; PATHOPHYSIOLOGY; PREGNANCY COMPLICATION; SPRAGUE DAWLEY RAT; SURGICAL INSTRUMENT; UTERUS; VASCULARIZATION;

ANIMALS; AORTA, ABDOMINAL; BLOOD PRESSURE; ENDOTHELIN-1; FEMALE; HEMODYNAMIC PROCESSES; HYPERTENSION; INTERLEUKIN-6; KIDNEY; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; RENAL CIRCULATION; RENIN; SURGICAL INSTRUMENTS; UTERUS;

EID: 33750588373     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000238442.33463.94     Document Type: Article

References (37)

1. Conrad KP, Benyo DF. Placental cytokines and the pathogenesis of peeclampsia. Am J Reprod Immunol. 1997;37:240-249.
2. Benyo DF, Smarason A, Redman CW, Sims C, Conrad KP. Expression of inflamatory cytokines in placentas from women with preeclampsia. J Clin Invest. 2001;86:2505-2512.
3. Kupferminc MJ, Peaceman AM, Wigton TR, Rehnberg KA, Socol ML. Tumor necrosis factor-α is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am J Obstet Gynecol. 1994;170:1752-1757.
4. Vince GS, Starkey PM, Austgulen R, Kwiatkowski D, Redman CW. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia. Br J Obstet Gynaecol. 1995;102:20-25.
5. Greer IA, Lyall F, Pereira T, Boswell F, Macara LM. Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with preeclampsia: a mechanism for endothelial dysfunction? Obstet Gynecol. 1994;84:937-940.
6. Kupferminc MJ, Peaceman AM, Wigtom TR, Rehnberg KA, Socol ML. Tumor necrosis factor-α is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am J Obstet Gynecol. 1994;170:1752-1759.
7. Funakoshi Y, Ichiki T, Ito K, Takeshita A. Induction of interleukin-6 expression by angiotensin II in rat vascular smooth muscle cells. Hypertension. 1999;34:118-125.
8. Han Y, Runge MS, Braiser AR. Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors. Circ Res. 1999;84:695-703.
9. Lee DL, Sturgis LC, Labazi H, Osborne JB Jr, Fleming C, Pollock JS, Manhiani M, Imig JD, Brands MW. Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am J Physiol Heart Circ Physiol. 2006;290:H935-H940.
10. Ruiz-Ortega M, Ruperez M, Lorenzo O, Esteban V, Blanco J, Mezzano S, Egido J. Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. Kidney Int. 2002;82:12-22.
11. Zhang ZH, Wei SG, Francis J, Felder RB. Cardiovascular and renal sympathetic activation by blood-borne TNF in rat: the role of central prostaglandins. Am J Physiol Regul Integr Comp Physiol. 2003;284:R916-R927.
12. Akira S, Taga T, Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol. 1993;54:1-78.
13. Wang P, Ba ZF, Chaudry IH. Administration of tumor necrosis factor-α in vivo depresses endothelium-dependent relaxation. Am J Physiol. 1994;266:H2535-H2541.
14. Lefer AM, Ma XL. Cytokines and growth factors in endothelial dysfunction. Crit Care Med. 1993;21:S9-S14.
15. Orshal JM, Khalil RA. Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6 infused pregnant rats. Hypertension. 2004;43:1-11.
16. Giardina JB, Green GM, Cockrell KL, Granger JP, Khalil RA. TNF enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats. Am J Physiol Regul Integr Comp. 2002;283:R130-R143.
17. Pober J, Cotran R. Cytokines and endothelial cell biology. Physiol Rev. 1990;70:427-451.
18. Granger JP, Alexander BT, Bennett WA, Khalil RA. Pathophysiology of pregnancy-induced hypertension. Am J Hyperten. 2001;14:S178-S185.
19. Granger JP, Alexander BT, Llinas MT, Bennett WA, Khalil RA. Pathophysiology of preeclampsia: linking placental ischemia/hypoxia with microvascular dysfunction. Microcirculation. 2002;9:147-160.
20. Granger JP, Alexander BT, Llinas MT, Bennett WA, Khalil RA. Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction. Hypertension. 2001;38:718-722.
21. Alexander BT, Cockrell K, Cline FD, Llinas MT, Sedeek M, Granger JP. Effect of angiotensin II synthesis blockade on the hypertensive response to chronic reductions in uterine perfusion pressure in pregnant rats. Hypertension. 2001;38:742-745.
22. Alexander BT, Rinewalt AN, Cockrell KL, Massey MB, Bennett WA, Granger JP. Endothelin type a receptor blockade attenuates the hypertension in response to chronic reductions in uterine perfusion pressure. Hypertension. 2001;37:485-489.
23. LaMarca BB, Bennett WA, Alexander BT, Cockrell K, Granger JP. Hypertension produced by reductions in uterine perfusion in the pregnant rat. Role of tumor necrosis factor-α. Hypertension. 2005;46:1022-1025.
24. LaMarca BB, Cockrell K, Sullivan E, Bennett W, Granger JP. Role of endothelin in mediating tumor necrosis factor-induced hypertension in pregnant rats. Hypertension. 2005;46:82-86.
25. Haber E, Koerner T, Page LB, Kliman B, Purnode A. Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjects. J Clin Endocr Metab. 1969;29:1349-1355.
26. Nakano J, Takizawa H, Ohtoshi T, Shoji S, Yamaguchi M, Ishii A, Yanagisawa M, Ito K. Endotoxin and pro-inflammatory cytokines stimulate endothelin-1 expression and release by airway epithelial cells. Clin Exper Allergy. 1994;24:330-336.
27. Mitchel MD, Schiller SL, Edwin SS. Endothelin production by amnion and its regulation by cytokines. Am J Obst Gynecol. 1991;165:120-124.
28. Yamashita J, Ogawa M, Nomura K, Matsuo S, Inada K, Yamashita S, Nakashima Y, Saishoji T, Takano S, Fujita S. Interleukin-6 stimulates the production of immunoreactive endothelin 1 in human breast cancer cells. Cancer Research. 1993;53:464-467.
29. Kahaleh MB, Fan PS. Effect of cytokines on the production of endothelin by endothelial cells. Clin Exp Rheumatol. 1997;15:163-167.
30. Kanse SM, Takahashi K, Lam H, Rees Andrew, Warren JB, Porta M, Molinatti P, Ghatei M, Bloom SR. Cytokine stimulated endothelin release from endothelial cells. Life Sci. 1991;48:1379-1384.
31. Hall JE, Brands NW. The renin-angiotensin-aldosterone systems: renal mechanisms and circulatory homeostasis. In: Laragh J and Brenner B, eds. The Kidney: Physiol and Pathophysiol. 2nd ed. New York, NY: Raven Press Ltd; 1992:1455-1504.
32. Faas MM, Schuiling GA, Baller JF, Visscher CA, Bakker WW. A new animal model for human preeclampsia: ultra low-dose endotoxin infusion in pregnant rats. Am J Obst Gynecol. 1994;171:158-164.
33. Cid MC, Kleinman HK, Grant DS, Schnaper HW, Fauci AS, Hoffman GS. Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNF-induced adhesion molecules E-selectin, intercellular adhesion molecule type 1, and vascular cell adhesion molecule type 1. J Clin Invest. 1994;93:17-25.
34. Conrad KP, Miles TM, Benyo DF. Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Rep Imm. 1998;40:102-111.
35. Kauma SW, Wang Y, Walsh SW. Preeclampsia is associated with decreased placental interleukin-6 production. J Soc Gynecol Invest. 1995;2:614-617.
36. Roberts JM, Lain KY. Recent insights into the pathogenesis of preeclampsia. Placenta. 2002;23:359-372.
37. Roberts JM, Pearson G, Cutler J, Lindheimer M. NHLBI Working Group on Research on Hypertension During Pregnancy. Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy. Hypertension. 2003;41:437-445.