Gingko biloba: Practical management of adverse effects and drug interactions

Canadian Pharmacists Journal

Volumn 139, Issue 5, 2006, Pages 32-35

  Sadler, Candace ^a   Charrois, Theresa L ^a   Vohra, Sunita ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CARE Program   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANTICONVULSIVE AGENT; CYCLOSPORIN; GINKGO BILOBA EXTRACT; PHENYTOIN; THEOPHYLLINE; WARFARIN;

ABDOMINAL PAIN; ARTICLE; ASTHMA; BLEEDING; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; DAILY LIFE ACTIVITY; DEMENTIA; DIARRHEA; DRUG MECHANISM; DRUG USE; DYSPEPSIA; HEADACHE; HEART PALPITATION; HUMAN; IMPOTENCE; INTERMITTENT CLAUDICATION; MEMORY DISORDER; META ANALYSIS; NAUSEA; PARESTHESIA; RETINA MACULA DEGENERATION; SEIZURE; SKIN ALLERGY; SKIN DEFECT; SYSTEMATIC REVIEW; VOMITING;

EID: 33750581637     PISSN: 17151635     EISSN: None     Source Type: Journal    
DOI: 10.1177/171516350613900508     Document Type: Article

References (32)

1. Ernst E. The risk-benefit profile of commonly used herbal therapies: gingko, St. John's wort, ginseng, echinacea, saw palmetto and kava. Ann Intern Med 2002;136(1):42-53.
2. Zeng X, Liu M, Yang Y, et al. Gingko biloba for acute ischemic stroke. Cochrane Database Syst Rev 2005;19(4):CD003691.
3. Natural medicines monograph. Gingko biloba. Natural Medicines Comprehensive Database 2006. Available: www.natural-database.com (accessed May 2006).
4. Evans JR. Gingko biloba for age-related macular degeneration. Cochrane Database Syst Rev 2000;(2):CD001775.
5. Wheatley D. Triple-blind, placebo-controlled trial of Gingko biloba in sexual dysfunction due to antidepressant drugs. Hum Psychopharmacol 2004;19(8):545-48.
6. Hilton M, Stuart E. Gingko biloba for tinnitus. Cochrane Database Syst Rev 2004;(2):CD003852.
7. Pittler MH, Ernst E. Gingko biloba extract for the treatment of intermittent claudication: a meta-analysis of randomized trials. Am J Med 2000;108(4):276-81.
8. Birks J, Grimley EV, Van Dongen M. Gingko biloba for cognitive impairment and dementia. Cochrane Database Syst Rev 2002;(4):CD003120.
9. Schneider LS, DeKosky ST, Farlow MR, et al. A randomized, double-blind, placebo-controlled trial of two doses of Gingko biloba extract in dementia of the Alzheimer's type. Curr Alzheimer Res 2005;2(5)A95-6.
10. Mix JA, Crews WD Jr. A double-blind, placebo-controlled, randomized trial of Gingko biloba extract Egb 761 in a sample of cognitively intact older adults: neuropsychological findings. Hum Psychopharmacol 2002;17(6):267-77.
11. Solomon PR, Adams F, Silver A, et al. Gingko for memory enhancement: a randomized controlled trial. JAMA 2002;288(7):835-40.
12. Quaranta L, Bettelli S, Uva MG, et al. Effect of Gingko biloba extract on preexisting visual field damage in normal tension glaucoma. Ophthalmology 2003;110(2):359-62.
13. Burrowes JD, Van Houten G. Herbs and dietary supplement use in patients with stage 5 chronic kidney disease. Nephrol Nurs J 2006;33(1):85-6.
14. Bent S, Goldberg H, Padula A, Avins AL. Spontaneous bleeding associated with Gingko biloba: a case report and systematic review of the literature. J Gen Intern Med 2005;20(7):657-61.
15. Bebbington A, Kulkarni R, Roberts P. Ginkgo biloba: persistent bleeding after total hip arthroplasty caused by herbal self-medication. J Arthroplasty 2005;20(1):125-6.
16. Kim SH, Lee EK, Chang JW, et al. Effects of Gingko biloba on haemostatic factors and inflammation in chronic peritoneal dialysis patients. Phytother Res 2005;19(6):546-8.
17. Yagmur E, Piatkowski A, Groger A, et al. Bleeding complication under Gingko biloba medication. Am J Hematol 2005;79(4):343-4.
18. Mills E, Wu P, Johnston BC, et al. Natural health product-drug interactions: a systematic review of clinical trials. Ther Drug Monit 2005;27(5):549-57.
19. Kupiec T, Vishnu, R. Fatal seizures due to potential herb-drug interactions with Gingko biloba. J Anal Toxicol 2005;29(7):755-8.
20. Granger AS. Gingko biloba precipitating epileptic seizures. Age Ageing 2001;30(6):523-5.
21. Shannon M, Anderson McElroy E, Liebelt EL. Toxic seizures in children: case scenarios and treatment strategies. Pediatr Emerg Care 2003;19(3):206-10.
22. He N, Edeki T. The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes. Am J Ther 2004;11(3):206-12.
23. Von Moltke LL, Weemhoff JL, Bedir E, et al. Inhibition of human cytochromes P450 by components of Gingko biloba. J Pharm Pharmacol 2004;56(8):1039-44.
24. Gaudineau C, Beckerman R, Welbourn S, Auclair K. Inhibition of human P450 enzymes by multiple constituents of the Gingko biloba extract. Biochem Biophys Res Commun 2004;318(4):1072-8.
25. Yin OQ, Tomlinson B, Wave MM, et al. Pharmacogenetics and herb-drug interactions: experience with Gingko biloba and omeprazole. Pharmacogenetics 2004;14(12):841-50.
26. Yasui-Furukori N, Furukori H, Kaneda A, et al. The effects of Gingko biloba on the pharmacokinetics and pharmacodynamics of donepezil. J Clin Pharmacol 2004;44(5):538-42.
27. Fowler JS, Wang GJ, Volkow ND, Logan J, Franceschi D, Franceschi M, et al. Evidence that Gingko biloba extract does not inhibit MAO A and B in human living brain. Life Sci 2000;66(9):PL141-6.
28. Sloley BD. Identification of kaempferol as a monoamine oxidase inhibitor. J Pharm Pharmacol 2000;52(4):451-9.
29. Kajiyama Y, Fujii K, Takeuchi H, Manabe Y. Gingko seed poisoning. Pediatrics 2002;109(2):325-7.
30. Kudolo GB. The effect of 3-month ingestion of Gingko biloba extract (Egb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus. J Clin Pharmacol 2001;41(6):600-11.
31. Kudolo GB, Wang W, Elrod R, et al. Short-term ingestion of Gingko biloba extract does not alter whole body insulin sensitivity in non-diabetic, pre-diabetic or type 2 diabetic subjects-a randomized double-blind placebo-controlled crossover study. Clin Nutr 2006;25(1):123-34.
32. Chandler F, editor. Herbs: everyday reference for health professionals. Ottawa: Canadian Pharmacists Association; 2000.