Hydroxyl radical scavenging by edaravone derivatives: Efficient scavenging by 3-methyl-1-(pyridin-2-yl)-5-pyrazolone with an intramolecular base

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 23, 2006, Pages 5939-5942

  Nakagawa, Hidehiko ^a   Ohyama, Ryo ^a   Kimata, Ayako ^a   Suzuki, Takayoshi ^a   Miyata, Naoki ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Anion form amount; Antioxidant; Pyrazolone derivatives

Indexed keywords

3 METHYL 1 (PYRIDIN 2 YL) 5 PYRAZOLONE; NORPHENAZONE; PYRAZOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG OXIDATION; DRUG SYNTHESIS; HYDROGEN BOND;

ANTIPYRINE; FREE RADICAL SCAVENGERS; HYDROXYL RADICAL; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PYRAZOLONES; PYRIDINES;

EID: 33750531845     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.005     Document Type: Article

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