Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 23, 2006, Pages 5978-5981

  Feng, Dennis ^a   Fisher, Michael ^a   Liang, Gui Bai ^a   Qian, Xiaoxia ^a   Brown, Chris ^a   Gurnett, Anne ^a   Leavitt, Penny Sue ^a   Liberator, Paul A ^a   Mathew, John ^a   Misura, Andrew ^a   Samaras, Samantha ^a   Tamas, Tamas ^a   Schmatz, Dennis M ^a   Wyvratt, Matthew ^a   Biftu, Tesfaye ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Coccidiosis; Imidazopyrimidine; Kinase; Parasite; PKG inhibitor

Indexed keywords

AMPROLIUM; COCCIDIOSTATIC AGENT; CYCLIC GMP DEPENDENT PROTEIN KINASE; PYRIDINE DERIVATIVE; SALINOMYCIN;

ANIMAL EXPERIMENT; ANIMAL FOOD; ARTICLE; CHICKEN; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; EIMERIA TENELLA; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; COCCIDIOSTATS; EIMERIA; IMIDAZOLES; MOLECULAR STRUCTURE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EIMERIA TENELLA; GALLUS GALLUS;

EID: 33750528715     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.08.127     Document Type: Article

References (7)

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5. All compounds were characterized by 1H NMR and LC/MS prior to submission for biological evaluation. 4.
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