Epinephrine increases the extracellular lidocaine concentration in the brain: A possible mechanism for increased central nervous system toxicity

Anesthesiology

Volumn 105, Issue 5, 2006, Pages 984-989

  Takahashi, Ryota ^a   Oda, Yutaka ^a   Tanaka, Katsuaki ^b   Morishima, Hisayo O ^c   Inoue, Koki ^a   Asada, Akira ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOSHIGAOKA KOSEINENKIN HOSPITAL   (Japan)

^c New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; LIDOCAINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NUCLEUS; BRAIN TOXICITY; BREATHING; CONTROLLED STUDY; CONVULSION; MALE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE ANALYSIS; RAT;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM; DRUG SYNERGISM; EPINEPHRINE; EXTRACELLULAR FLUID; INFUSIONS, INTRAVENOUS; LIDOCAINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

EID: 33750490777     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/00000542-200611000-00020     Document Type: Article

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