Meglumine Eicosapentaenoic acid (MeEPA) a new soluble omega-3 fatty acid formulation: In vitro bladder cancer cytotoxicity tests in combination with epirubicin and mitomycin

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 75, Issue 6, 2006, Pages 367-373

  Mackie, S J ^a   Sharma, D M ^a   Cooper, A J ^a   Harris, N M ^a   Lwaleed, B A ^a  

^a UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPIRUBICIN; ICOSAPENTAENOIC ACID; MEGLUMINE EICOSAPENTAENOIC ACID; MITOMYCIN; TETRAZOLIUM; UNCLASSIFIED DRUG;

AGED; ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; BIOMASS; BLADDER CANCER; CANCER CELL CULTURE; CELL ASSAY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG EXPOSURE; DRUG FORMULATION; DRUG MEGADOSE; DRUG POTENTIATION; DRUG SOLUBILITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; DRUG COMBINATIONS; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; EICOSAPENTAENOIC ACID; EPIRUBICIN; FATTY ACIDS, OMEGA-3; HUMANS; MEGLUMINE; MITOMYCIN; URINARY BLADDER NEOPLASMS;

EID: 33750483260     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plefa.2006.07.002     Document Type: Article

References (24)

1. Office for National Statistics, Bladder Cancer Trends, Internet communication, 2004.
2. P.R. Carroll, Smith's General Urology, Lange/McGraw-Hill, 2000, pp. 355-377.
3. Prout Jr. G.R., Barton B.A., Griffin P.P., and Friedel G.H. Treated history of noninvasive grade 1 transitional cell carcinoma. The National Bladder Cancer Group. J. Urol. 148 (1992) 1413-1419
4. Heney N.M., Ahmed S., Flanagan M.J., Frable W., Corder M.P., Hafermann M.D., and Hawkins I.R. Superficial bladder cancer: progression and recurrence. J. Urol. 130 (1983) 1083-1086
5. Shelley M.D., Kynaston H., Court J., Wilt T.J., Coles B., Burgon K., and Mason M.D. A systematic review of intravesical bacillus Calmette-Guerin plus transurethral resection vs transurethral resection alone in Ta and T1 bladder cancer. BJU Int. 88 (2001) 209-216
6. Huncharek M., Geschwind J.F., Witherspoon B., McGarry R., and Adcock D. Intravesical chemotherapy prophylaxis in primary superficial bladder cancer: a meta-analysis of 3703 patients from 11 randomized trials. J. Clin. Epidemiol. 53 (2000) 676-680
7. Kromhout D. Epidemiology of cardiovascular diseases in Europe. Public Health Nutr. 4 (2001) 441-457
8. Shimizu T., Fujii T., Suzuki R., Igarashi J., Ohtsuka Y., Nagata S., and Yamashiro Y. Effects of highly purified eicosapentaenoic acid on erythrocyte fatty acid composition and leukocyte and colonic mucosa leukotriene B4 production in children with ulcerative colitis. J. Pediatr. Gastroenterol. Nutr. 37 (2003) 581-585
9. Calder P.C., and Zurier R.B. Polyunsaturated fatty acids and rheumatoid arthritis. Curr. Opin. Clin. Nutr. Metab. Care 4 (2001) 115-121
10. K. Simmer, Longchain polyunsaturated fatty acid supplementation in infants born at term, Cochrane Database Syst. Rev. 2001, CD000376-.
11. Leitzmann M.F., Stampfer M.J., Michaud D.S., Augustsson K., Colditz G.C., Willett W.C., and Giovannucci E.L. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. Am. J. Clin. Nutr. 80 (2004) 204-216
12. Astorg P. Dietary N-6 and N-3 polyunsaturated fatty acids and prostate cancer risk: a review of epidemiological and experimental evidence. Cancer Causes Control 15 (2004) 367-386
13. Dewailly E., Mulvad G., Sloth P.H., Hansen J.C., Behrendt N., and Hart Hansen J.P. Inuit are protected against prostate cancer. Cancer Epidemiol. Biomarkers Prev. 12 (2003) 926-927
14. Wang J., Huang C., and Li S. Research progress on dietary fat and the development of lung cancer. Wei Sheng Yan Jiu 33 (2004) 383-385
15. Takezaki T., Inoue M., Kataoka H., Ikeda S., Yoshida M., Ohashi Y., Tajima K., and Tominaga S. Diet and lung cancer risk from a 14-year population-based prospective study in Japan: with special reference to fish consumption. Nutr. Cancer 45 (2003) 160-167
16. Eynard A.R. Is the risk of urinary tract tumorigenesis enhanced by a marginal chronic essential fatty acid deficiency (EFAD)?. Nutrition 14 (1998) 211-216
17. Jiang W.G., Bryce R.P., and Horrobin D.F. Essential fatty acids: molecular and cellular basis of their anti-cancer action and clinical implications. Crit. Rev. Oncol. Hematol. 27 (1998) 179-209
18. Zijlstra J.G., de Vries E.G., Muskiet F.A., Martini I.A., Timmer-Bosscha H., and Mulder N.H. Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin-sensitive and -resistant small-cell lung cancer cell lines, and on cytotoxicity in the tumor cell lines. Int. J. Cancer 40 (1987) 850-856
19. Davies C.L., Loizidou M., Cooper A.J., and Taylor I. Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. Eur. J. Cancer 35 (1999) 1534-1540
20. Solomon L.Z., Jennings A.M., Hayes M.C., Bass P.S., Birch B.R., and Cooper A.J. Is gamma-linolenic acid an effective intravesical agent for superficial bladder cancer? In vitro cytotoxicity and in vivo tolerance studies. Urol. Res. 26 (1998) 11-15
21. Harris N.M., Anderson W.R., Lwaleed B.A., Cooper A.J., Birch B.R., and Solomon L.Z. Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. Cancer 97 (2003) 71-78
22. Falconer J.S., Ross J.A., Fearon K.C., Hawkins R.A., O'Riordain M.G., and Carter D.C. Effect of eicosapentaenoic acid and other fatty acids on the growth in vitro of human pancreatic cancer cell lines. Br. J. Cancer 69 (1994) 826-832
23. Rose D.P., Connolly J.M., and Liu X.H. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. Nutr. Cancer 24 (1995) 33-45
24. Rose D.P., Connolly J.M., Rayburn J., and Coleman M. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. J. Natl. Cancer Inst. 87 (1995) 587-592