Stem cells: A regenerative pharmaceutical

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 50, Issue 3, 2006, Pages 205-216

  Shanthly, N ^a   Aruva, M R ^a   Zhang, K ^a   Mathew, B ^a   Thakur, Mathew L ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Hematopoietic stem cells; Stem cells; Totipotent stem cell

Indexed keywords

6 FLUORODOPA F 18; 8 QUINOLINOL INDIUM IN 111; FLUORODEOXYGLUCOSE F 18; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PYRUVALDEHYDE BI(N4 METHYLTHIOSEMICARBAZONE) CU 64; TRACER; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ALZHEIMER DISEASE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CARCINOGENICITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; CELL RENEWAL; CORD BLOOD STEM CELL TRANSPLANTATION; DIABETES MELLITUS; DRUG HALF LIFE; EMBRYONIC STEM CELL; HEART INFARCTION; HUMAN; ISOTOPE LABELING; KIDNEY CANCER; MULTIPOTENT STEM CELL; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PARKINSON DISEASE; PLURIPOTENT STEM CELL; POSITRON EMISSION TOMOGRAPHY; RADIATION DETECTION; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPINAL CORD INJURY; STEM CELL TRANSPLANTATION; TOTIPOTENT STEM CELL;

HUMANS; ISOTOPE LABELING; RADIOISOTOPES; RADIOPHARMACEUTICALS; REGENERATION; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 33750463393     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (60)

1. Herzog EL, Chai L, Krause DS. Plasticity of marrow-derived stem cells. Blood 2003;102:3483-93.
2. National Institutes of Health (NIH), Department of Health and Human Services. Stem cells: scientific progress and future research directions. Bethesda, MD: NIH; 2001, Chapter 4, p.27.
3. Ferrari G, Cusella G, Angelis D, Coletta M, Paolucci E, Stornaiuolo A et al. Regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-30.
4. Akashi K, Traver D, Miyamoto T, Weissmann IL. Clonogenic commom myeloid progenitor that gives rise to all myeloid lineages. Nature 2000;404:193-7.
5. Weissmann IL. Stem cells: units of development, units of regeneration and units in evolution. Cell 2000;404:157-68.
6. National Institutes of Health (NIH), Department of Health and Human Services. Stem cells: scientific progress and future research directions. Bethesda, MD: NIH; 2001, Chapter 5, p.44.
7. Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290:1779-82.
8. Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999;283:534-7.
9. Slack JMW. Stem cells in epithelial tissues. Science 2000;287:1431-3.
10. Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 1993;4:713-24.
11. Sanchez-Ramos JR. Neural cells derived from adult bone marrow and umbilical cord blood. J Neurosci Res 2002;69:880-93.
12. Goodwin HS, Bicknese AR, Chien SN, Bogucki BD, Quinn CO, Wall DA. Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant 2001;11:581-8.
13. Bongso A, Fong CY, Ng SC, Ratnam S. Isolation and culture of inner cell mass cells from human blastocysts. Hum Reprod 1994;9:2110-7.
14. Odorico JS, Kaufman DS, Thompson JA. Multilineage differentiation from human embryonic stem cell lines. Stem Cells 2001;19:193-204.
15. Thomson JA, Eldor JI, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-7.
16. Thomson JA, Odorico JS. Human embryonic stem cell and embryonic germ cell lines. Trends Biotechnol 2000;18:53-7.
17. Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol 2000;18:399-404. Erratum in: Nat Biotechnol 2000;18:559.
18. Thomson JA, Odorico. Human embryonic stein cell and embryonic germ cell lines. Trends Biotechnol 2000;2:53-7.
19. Turnpennya L, Brickwooda S, Spallutoa CM, Pipera K, Cameronb IT, Wilsona DI et al. Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells. Stem Cells 2003;21:598-609.
20. Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP et al. Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med 2004;350:1353-6.
21. Brustle O, Choudhary K, Karram K, Huttner A, Murray K, Dubois-Dalcq M et al. Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats. Nat Biotechnol 1998;11:1040-4.
22. Villa B. Genetics, inflammation, statin treatment and gene therapy. IDrugs 2000;3:1166-8.
23. Sawamoto K, Nakao N, Kakishita K, Ogawa Y, Toyama Y, Yamamoto A et al. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J Neurosci 2001;21:3895-903.
24. Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1998;4:290-5.
25. Hayek A, Beattie GM. Processing, storage and experimental transplantation of human fetal pancreatic cells. Ann Transplant 1997;23:46-54.
26. Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ et al. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci U S A 1998;95:13726-31.
27. National Institutes of Health (NIH), Department of Health and Human Services. Stem cells: scientific progress and future research directions. Bethesda, MD: NIH; 2001, Chapter 3, p.112.
28. Laughlin, MJ. Umbilical cord blood for allogeneic transplantation in children and adults. Bone Marrow Transplant 2001;27:1-6.
29. Tsokos GC, Nepom GT. Gene therapy in the treatment of autoimmune diseases. J Clin Invest 2000;106:181-3.
30. Traynor AE, Schroeder J, Rosa RM, Cheng D, Stefka J, Mujais S et al. Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem-cell transplantation: a phase I study. Lancet 2000;56:701-7.
31. Prud'homme GJ. Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors. J Gene Med 2000;2:222-32.
32. Lawson BR, Prud'homme GJ, Chang Y, Gardner HA, Kuan J, Kono DH et al. Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc. J Clin Invest 2000;106:207-15.
33. Beattie GM, Otonkoski T, Lopez AD, Hayek A. Functional beta-cell mass after transplantation of human fetal pancreatic cells: differentiation or proliferation? Diabetes 1997;46:244-8.
34. Tour DD, Halvorsen T, Demeterco C, Tyrberg B, Itkin-Ansari, P, Loy M et al. B-cell differentiation from a human pancreatic cell line in vitro and in vivo. Mol Endocrinol 2001;15:476-83.
35. Itkin-Ansari P, Demeterco C, Bossie S, Tour DD, Beattie GM, Movassat J et al. PDX-1 and cell-cell contact act in synergy to promote d-cell development in a human pancreatic endocrine precursor cell line. Mol Endocrinol 2001;14:814-22.
36. Soria B, Roche E, Berná G, Leon-Quinto T, Reig JA, Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin induced diabetic mice. Diabetes 2000;49:157-62.
37. National Institutes of Health (NIH), Department of Health and Human Services. Stem cells: scientific progress and future research directions. Bethesda, MD: NIH; 2001, Chapter 7, p.73.
38. Quinn NP. The clinical application of cell grafting techniques in patients with Parkinson's disease. Prog Brain Res 1990;82:619-25.
39. Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001;344:710-9.
40. Liu S, Qu Y, Stewart TJ, Howard MJ, Chakrabortty S, Holekamp TF et al. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci U S A 2000;97:6126-31.
41. McDonald JW, Liu XZ, Qu Y, Liu S, Mickey SK, Turetsky D et al. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med 1999;5:1410-2.
42. Raisman G. Olfactory ensheathing cells: another miracle cure for spinal cord injury? Nat Rev Neurosci 2001;2:369-74.
43. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-5.
44. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001;107:1-8.
45. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M et al. Differentiation of human embryonic stem cells into embryoid bodies comprising the three embryonic germ layers. Mol Med 2000;6:88-95.
46. Jones JM, Thompson JA. Human embryonic stem cell therapy. Semin Reprod Med 2000;18:219-23.
47. Rathjen PD, Lake J, Whyatt LM, Bettess MD, Rathjen J. Properties and uses of embryonic stem cells: prospects for application to human biology and gene therapy. Reprod Fertil Dev 1998;10:31-47.
48. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-11.
49. Guenin LM. A proposed stem cell research policy. Stem Cells 2005;23:1023-7.
50. Xu RH, Peck RM, Li DS, Feng X, Ludwig T, Thomson JA, Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2005;2:185-90.
51. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-7.
52. Miyamoto T, Weissman IL, Akashi K. AML1/ETO-expressing non-leukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation. Proc Natl Acad Sci U S A 2000;97:7521-6.
53. Reubinoff BE, Pera MF, Vajta G, Trounson AO. Effective cryop-reservation of human embryonic stem cells by the open pulled straw vitrification method. Hum Reprod 2001;16:2187-94.
54. Eiges R, Schuldiner M, Drukker M, Yanuka O, Itskovitz-Eldor J, Benvenisty N. Establishment of human embryonic stem cell-transduced clones carrying a marker of undifferentiated cells. Curr Biol 2001;11:514-8.
55. Julius MH, Masuda T, Herzenberg LA. Demonstration that antigen-binding cells are precursors of antibody-producing cells after purification with a fluorescence-activated cell sorter. Proc Natl Acad Sci U S A 1972;69:1934-8.
56. Sarkhosh K, Tredget EE, Uludag H, Kilani RT, Karami A, Li Y et al. Temperature-sensitive polymer-conjugated IFN-gamma induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG). J Cell Physiol 2004;201:146-54.
57. 111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model. J Nucl Med 2004;45:512-8.
58. 111In oxine labeled mesenchymal stem cell SPECT after intravenous administration in myocardial infarction. Nucl Med Commun 2003;24:1149-54.
59. Zhou R, Thomas DH, Qiao H, Bal HS, Choi SR, Alavi A et al. In vivo detection of stem cells grafted in infarcted rat myocardium. J Nucl Med 2005;46:816-22.
60. Vogel G. Stem cells. Scientists chase after immortality in a petri dish. Science 2005;309:1982-3.