Cofabrication of electromagnets and microfluidic systems in poly(dimethylsiloxane)

Angewandte Chemie - International Edition

Volumn 45, Issue 41, 2006, Pages 6877-6882

  Siegel, Adam C ^a   Shevkoplyas, Sergey S ^a   Weibel, Douglas B ^a   Bruzewicz, Derek A ^a   Martinez, Andres W ^a   Whitesides, George M ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Analytical chemistry; Electromagnets; Magnetochemistry; Metal polymer materials; Microfluidic systems

Indexed keywords

ELECTRIC CURRENTS; ELECTROMAGNETS; FABRICATION; MAGNETIC FIELD EFFECTS; POLYSILICON; SUPERPARAMAGNETISM;

COFABRICATION; MAGNETOCHEMISTRY; METAL POLYMER MATERIALS; MICROFLUIDIC CHANNELS;

FLUIDICS;

BAYSILON; DIMETICONE; SILICONE DERIVATIVE;

ARTICLE; CHEMISTRY; ELECTROMAGNETIC FIELD; INSTRUMENTATION; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; SURFACE PROPERTY;

DIMETHYLPOLYSILOXANES; ELECTROMAGNETICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; SILICONES; SURFACE PROPERTIES;

EID: 33750453744     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200602273     Document Type: Article

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38. Refs. [16], [21], and [22] report slightly different formulas for calculating the force upon a superparamagnetic bead as a function of the gradient of the magnetic field. Our model is based on the formula reported in Ref. [21]; in this model, we neglect any initial magnetization of the superparamagnetic beads and do not consider the inertia of the beads, the contribution of the channel walls to the drag on the beads, or the magnetic susceptibility of the suspending medium.
39. We purchased COMPEL superparamagnetic beads (5.9-μm diameter) from Bangs Laboratories, Inc. We calculated the magnetic susceptibility of the beads χ using the magnetization curves provided by the manufacturer. The susceptibility ranges from χ = 0.174 at low magnetic fields (0.0-0.5 mT) to χ = 0.167 at high magnetic fields (1.0-3.0 mT); the value of susceptibility that we use (χ = 0.170), is the average value calculated over the general range of applied magnetic fields 0.0-3.0 mT used in our experiments.