Investigation into the potential of low-frequency ultrasound facilitated topical delivery of Cyclosporin A

International Journal of Pharmaceutics

Volumn 326, Issue 1-2, 2006, Pages 32-38

  Liu, Hongzhuo ^a   Li, Sanming ^a   Pan, Weisan ^a   Wang, Yongjun ^a   Han, Fei ^a   Yao, Huimin ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Chemical enhancer; Cyclosporin A; Eletroporation; Low frequency ultrasound; Synergistic

Indexed keywords

CYCLOSPORIN A; DODECYL SULFATE SODIUM; LAUROCAPRAM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG PENETRATION; DRUG TRANSPORT; ELECTROPORATION; IONTOPHORESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PENETRATION; TOPICAL TREATMENT; ULTRASOUND;

ADMINISTRATION, CUTANEOUS; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CYCLOSPORINE; DIFFUSION; DRUG ADMINISTRATION ROUTES; DRUG DELIVERY SYSTEMS; ELECTROPORATION; IMMUNOSUPPRESSIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; ULTRASONICS;

EID: 33750441110     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.07.022     Document Type: Article

References (40)

1. Benson H.A.E., McElnay J.C., and Harland R. Phonophoresis of lingocaine and prilocaine from EMLA cream. Int. J. Pharm. 44 (1988) 65-69
2. Boinpally R.R., Zhou S.L., Devraj G., Anne P.K., Poondru S., and Jasti B.R. Iontophoresis of lecithin vesicles of Cyclosporin A. Int. J. Pharm. 274 (2004) 185-190
3. Boucaud A., Machet L., Arbeille B., Machet M.C., Sournac M., Mavon A., Patat F., and Vaillant L. In vitro study of low-frequency ultrasound-enhanced transdermal transport of fentanyl and caffeine across human and hairless rat skin. Int. J. Pharm. 228 (2001) 69-77
4. Boucaud A., Garrigue M.A., Machet L., Vaillant L., and Patat F. Effect of sonication parameters on transdermal delivery of insulin to hairless rats. J. Pharm. Sci. 91 (2002) 113-119
5. Choi H.K., and Flynn G.L. Percutaneous absorption and dermal delivery of Cyclosporin A. J. Pharm. Sci. 84 (1995) 581-583
6. Dimitrov D.S., and Sowers A.E. Membrane electroporation-fast molecular exchange by electroosmosis. Biochim. Biophys. Acta. 1022 (1990) 381-392
7. Duncan J.I., Payne S.N., Winfield A.J., Ormerod A.D., and Thomson A.W. Enhanced percutaneous absorption of a novel topical Cyclosporin A formulation and assessment of its immunosuppressive activity. Br. J. Dermatol. 123 (1990) 631-640
8. Edwards D.A., Prausnitz M.R., Langer R., and Weaver J.C. Analysis of enhanced transdermal transport by skin electroporation. J. Control. Release 34 (1995) 211-221
9. Guzzo C. Recent advances in the treatment of psoriasis. Dermatol. Clin. 15 (1997) 59-68
10. Hultsch T., Kapp A., and Spergel J. Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis. Dermatology 211 (2005) 174-187
11. IIana L., and Joseph K. Ultrasound and transdermal drug delivery. Drug. Deliv. Today 9 (2004) 670-675
12. Johnson M.E., Mitragotri S., Patel A., Blankschtein D., and Langer R. Synergistic effect of ultrasound and chemical enhancers on transdermal drug delivery. J. Pharm. Sci. 85 (1996) 670-679
13. Klenchin V.A., Sukharev S.I., Serov S.M., Chernomordik L.V., and Chizmadzhev Y.A. Electrically induced DNA uptake by cells is a fast process involving DNA electrophoresis. Biophys. J. 60 (1991) 804-811
14. Kost J., Pliquett U., Mitragotri S., Yamamoto A., Weaver J., and Langer R. Enhanced transdermal delivery: synergistic effect of ultrasound and electroporation. Pharm. Res. 13 (1996) 633-638
15. Lallemand F., Felt-Byeyens O., Besseghir K., Benar-Cohen F., and Gumy R. Cyclosporin A delivery to the eye: a pharmaceutical challenge. Eur. J. Pharm. Biopharm. 56 (2003) 307-318
16. Lavon I., Grossman N., and Kost J. The nature of ultrasound-SLS synergism during enhanced transdermal transport. J. Control. Release 107 (2005) 484-494
17. Liu H., Li S., Wang Y., Han F., and Dong Y. Bicontinuous water-AOT/Tween85-isopropylmytistate microemulsion: a new vehicle for transdermal delivery of Cyclosporin A. Drug. Dev. Ind. Pharm. 32 (2006) 549-557
18. Liu H., Li S., Wang Y., Yao H., and Zhang Y. Effect of vehicles and enhancers on the topical delivery of cyclosporin A. Int. J. Pharm. 311 (2006) 182-186
19. Lopes L.B., Collett J.H., and Bentley M.V.L.B. Topical delivery of Cyclosporin A: an in vitro study using monoolein as a penetration enhancer. Eur. J. Pharm. Biopharm. 60 (2005) 25-30
20. Machet L., and Boucaud A. Phonophoresis: efficiency, mechanisms and skin tolerance. Int. J. Pharm. 243 (2002) 1-15
21. Mitragotri S. Synergistic effect of enhancers for transdermal drug delivery. Pharm. Res. 17 (2000) 1354-1359
22. Mitragotri S., Blankschtein D., and Langer R. Ultrasound-mediated transdermal protein delivery. Science 269 (1995) 850-853
23. Mitragotri S., Blankschtein D., and Langer R. Transdermal drug delivery using low-frequency sonophoresis. Pharm. Res. 13 (1996) 411-420
24. Mitragotri S., Ray D., Farrell J., Tang H., Yu B., Kost J., Blankschtein D., and Langer R. Enhancement of transdermal transport using ultrasound and surfactants. Proc. Ind. Symp. Control. Release Bioact. Mater. 26 (1999) 176-177
25. Mitragotri S., Farrell J., Tang H., Terahara T., Kost J., and Langer R. Determination of threshold energy dose for ultrasound induced transdermal drug transport. J. Control. Release 63 (2000) 41-52
26. Mitragotri S., Ray D., Farrell J., Tang H., Yu B., Kost J., Blankschtein D., and Langer R. Synergistic effect of ultrasound and sodium lauryl sulphate on transdermal drug delivery. J. Pharm. Sci. 89 (2000) 892-900
27. Mitragotri S., and Kost J. Transdermal delivery of heparin and low-molecular weight heparin using low frequency ultrasound. Pharm. Res. 18 (2001) 1151-1156
28. Mitragotri S., and Kost J. Low-frequency sonophoresis. Adv. Drug Deliv. Rev. 56 (2004) 589-601
29. Prausnitz M.R., Corbett J.D., Gimm J.A., Golan D.E., Langer R., and Weaver J.C. Millisecond measurement of transport during and after an electroporation pulse. Biophys. J. 68 (1995) 1864-1870
30. Santoianni P., Nino M., and Calabro G. Intradermal drug delivery by low-frequency sonophoresis (25 kHz). Dermatol. Online J. 10 (2004) 24
31. Tang H., Joanne Wang C.C., Blankschtein D., and Langer R. An investigation of the role of cavitation in low-frequency ultrasound mediated transdermal drug transport. Pharm. Res. 19 (2002) 1160-1169
32. Tachibana K. Transdermal delivery of insulin to alloxan-diabetic rabbits by ultrasound exposure. Pharm. Res. 9 (1992) 952-954
33. Terahara T., Mitragotri S., Kost J., and Langer R. Dependence of low-frequency sonophoresis on ultrasound parameters: distance of the horn and intensity. Int. J. Pharm. 235 (2002) 35-42
34. Tezel A., Sens A., Tuscherer J., and Mitragotri S. Frequency dependence of sonophoresis. Pharm. Res. 18 (2001) 1694-1700
35. Tran H.S., Malli D., Chrzanowski F.A., Puc M.M., Matthews M.S., and Hewitt C.W. Site-specific immunosuppression using a new formulation of topical cyclosporine A with polyethylene glycol-8 glyceryl caprylate/caprate. J. Surg. Res. 83 (1999) 136-140
36. Verma D.D., Verma S., McElwee K.J., Freyschmidt P.P., Hoffman R., and Fahr A. Treatment of alopecia areata in the DEBR model using Cyclosporin A lipid vesicles. Eur. J. Dermatol. 14 (2004) 332-338
37. Verma D.D., and Fahr A. Synergistic penetration enhancement effect of ethanol and phosphoilipids on the topical delivery of Cyclosporin A. J. Control. Release 97 (2004) 55-66
38. Vc H. The use of cyclosporin in psoriasis: a clinical review. Br. J. Dermatol. 150 (2004) 671-710
39. Wang S., Kara M., and Krishnan T.R. Transdermal delivery of Cyclosporin A using electroporation. J. Control. Release 50 (1998) 61-70
40. Zachariae H., Kragballe K., and Hansen H. Renal biopsy findings in long-term cyclosporin treatment of psoriasis. Br. J. Dermatol. 136 (1997) 531-535