메뉴 건너뛰기




Volumn 95, Issue 9, 2006, Pages 1202-1211

The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

Author keywords

Cytotoxic T cell; Immunotherapy; Polycomb; Regulatory T cell; Tumour antigens

Indexed keywords

EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; EPITOPE; GAMMA INTERFERON; PROTEIN BMI 1; PROTEIN EZH 2; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 33750431017     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603369     Document Type: Article
Times cited : (41)

References (44)
  • 3
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K (2003) EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J 22: 5323-5335
    • (2003) EMBO J , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 7
    • 2342537869 scopus 로고    scopus 로고
    • The promise of cancer vaccines
    • Gilboa E (2004) The promise of cancer vaccines. Nat Rev Cancer 4: 401-411
    • (2004) Nat Rev Cancer , vol.4 , pp. 401-411
    • Gilboa, E.1
  • 9
    • 28544450393 scopus 로고    scopus 로고
    • Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1
    • Hernandez-Munoz I, Taghavi P, Kuijl C, Neefjes J, van Lohuizen M (2005) Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1. Mol Cell Biol 25: 11047-11058
    • (2005) Mol Cell Biol , vol.25 , pp. 11047-11058
    • Hernandez-Munoz, I.1    Taghavi, P.2    Kuijl, C.3    Neefjes, J.4    Van Lohuizen, M.5
  • 10
    • 0037150730 scopus 로고    scopus 로고
    • Polycomb repression: From cellular memory to cellular proliferation and cancer
    • Jacobs JJ, van Lohuizen M (2002) Polycomb repression: from cellular memory to cellular proliferation and cancer. Biochim Biophys Acta 1602: 151-161
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 151-161
    • Jacobs, J.J.1    Van Lohuizen, M.2
  • 11
    • 9244248707 scopus 로고    scopus 로고
    • Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer
    • Kim JH, Yoon SY, Jeong SH, Kim SY, Moon SK, Joo JH, Lee Y, Choe IS, Kim JW (2004) Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer. Breast 13: 383-388
    • (2004) Breast , vol.13 , pp. 383-388
    • Kim, J.H.1    Yoon, S.Y.2    Jeong, S.H.3    Kim, S.Y.4    Moon, S.K.5    Joo, J.H.6    Lee, Y.7    Choe, I.S.8    Kim, J.W.9
  • 13
    • 0031113988 scopus 로고    scopus 로고
    • Conserved CTL epitopes within EBV latent membrane protein 2: A potential target for CTL-based tumor therapy
    • Lee SP, Tierney RJ, Thomas WA, Brooks JM, Rickinson AR (1997) Conserved CTL epitopes within EBV latent membrane protein 2: a potential target for CTL-based tumor therapy. J Immunol 158: 3325-3334
    • (1997) J Immunol , vol.158 , pp. 3325-3334
    • Lee, S.P.1    Tierney, R.J.2    Thomas, W.A.3    Brooks, J.M.4    Rickinson, A.R.5
  • 14
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 16
    • 0029835516 scopus 로고    scopus 로고
    • Differential anti-MART-1/MelanA CTL activity in peripheral blood of HLA-A2 melanoma patients in comparison to healthy donors: Evidence of in vivo priming by tumor cells
    • Marincola FM, Rivoltini L, Salgaller ML, Player M, Rosenberg SA (1996) Differential anti-MART-1/MelanA CTL activity in peripheral blood of HLA-A2 melanoma patients in comparison to healthy donors: evidence of in vivo priming by tumor cells. J Immunother Emphasis Tumor Immunol 19: 266-277
    • (1996) J Immunother Emphasis Tumor Immunol , vol.19 , pp. 266-277
    • Marincola, F.M.1    Rivoltini, L.2    Salgaller, M.L.3    Player, M.4    Rosenberg, S.A.5
  • 17
    • 0015539979 scopus 로고
    • Release of infectious Epstein-Barr virus by transformed marmoset leukocytes
    • Miller G, Lipman M (1973) Release of infectious Epstein-Barr virus by transformed marmoset leukocytes. Proc Natl Acad Sci USA 70: 190-194
    • (1973) Proc Natl Acad Sci USA , vol.70 , pp. 190-194
    • Miller, G.1    Lipman, M.2
  • 18
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 20
    • 3943110235 scopus 로고    scopus 로고
    • Identification of polycomb group protein enhancer of zeste homolog 2 (EZH2)-derived peptides immunogenic in HLA-A24+ prostate cancer patients
    • Ogata R, Matsueda S, Yao A, Noguchi M, Itoh K, Harada M (2004) Identification of polycomb group protein enhancer of zeste homolog 2 (EZH2)-derived peptides immunogenic in HLA-A24+ prostate cancer patients. Prostate 60: 273-281
    • (2004) Prostate , vol.60 , pp. 273-281
    • Ogata, R.1    Matsueda, S.2    Yao, A.3    Noguchi, M.4    Itoh, K.5    Harada, M.6
  • 21
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy LA, Hilleman T, Wedemeyer H, Manns MP, Greten TF, Korangy F (2005) Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res 65: 2457-2464
    • (2005) Cancer Res , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hilleman, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 22
    • 0028052724 scopus 로고
    • Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
    • Parker KC, Bednarek MA, Coligan JE (1994) Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J Immunol 152: 163-172
    • (1994) J Immunol , vol.152 , pp. 163-172
    • Parker, K.C.1    Bednarek, M.A.2    Coligan, J.E.3
  • 23
    • 0033765302 scopus 로고    scopus 로고
    • Exploitation of the B cell repertoire for the identification of human tumour antigens
    • Pfreundschuh M (2000) Exploitation of the B cell repertoire for the identification of human tumour antigens. Cancer Chemother Pharmacol 46(Suppl): S3-S7
    • (2000) Cancer Chemother Pharmacol , vol.46 , Issue.SUPPL.
    • Pfreundschuh, M.1
  • 24
    • 0141670822 scopus 로고    scopus 로고
    • Self-renewal of hematopoietic and leukemic stem cells: A central role for the polycomb-group gene Bmi-1
    • Raaphorst FM (2003) Self-renewal of hematopoietic and leukemic stem cells: a central role for the polycomb-group gene Bmi-1. Trends Immunol 24: 522-524
    • (2003) Trends Immunol , vol.24 , pp. 522-524
    • Raaphorst, F.M.1
  • 26
    • 1542349930 scopus 로고    scopus 로고
    • Site-specific expression of polycomb-group genes encoding the HPC-HPH/PRC1 complex in clinically defined primary nodal and cutaneous large B-cell lymphomas
    • Raaphorst FM, Vermeer M, Fieret E, Blokzijl T, Dukers D, Sewalt RG, Otte AP, Willemze R, Meijer CJ (2004) Site-specific expression of polycomb-group genes encoding the HPC-HPH/PRC1 complex in clinically defined primary nodal and cutaneous large B-cell lymphomas. Am J Pathol 164: 533-542
    • (2004) Am J Pathol , vol.164 , pp. 533-542
    • Raaphorst, F.M.1    Vermeer, M.2    Fieret, E.3    Blokzijl, T.4    Dukers, D.5    Sewalt, R.G.6    Otte, A.P.7    Willemze, R.8    Meijer, C.J.9
  • 27
    • 0036069776 scopus 로고    scopus 로고
    • Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease
    • Reynolds GM, Billingham LJ, Gray LJ, Flavell JR, Najafipour S, Crocker J, Nelson P, Young LS, Murray PG (2002) Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease. Br J Haematol 118: 195-201
    • (2002) Br J Haematol , vol.118 , pp. 195-201
    • Reynolds, G.M.1    Billingham, L.J.2    Gray, L.J.3    Flavell, J.R.4    Najafipour, S.5    Crocker, J.6    Nelson, P.7    Young, L.S.8    Murray, P.G.9
  • 28
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg SA (2001) Progress in human tumour immunology and immunotherapy. Nature 411: 380-384
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 29
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg SA, Yang JC, Restifo NP (2004) Cancer immunotherapy: moving beyond current vaccines. Nat Med 10: 909-915
    • (2004) Nat Med , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 30
    • 24944495579 scopus 로고    scopus 로고
    • Direct evidence on the immune-mediated spontaneous regression of human cancer: An incentive for pharmaceutical companies to develop a novel anti-cancer vaccine
    • Saleh F, Renno W, Klepacek I, Ibrahim G, Asfar S, Dashti H, Romero P, Dashti A, Behbehani A (2005) Direct evidence on the immune-mediated spontaneous regression of human cancer: an incentive for pharmaceutical companies to develop a novel anti-cancer vaccine. Curr Pharm Des 11: 3461-3473
    • (2005) Curr Pharm des , vol.11 , pp. 3461-3473
    • Saleh, F.1    Renno, W.2    Klepacek, I.3    Ibrahim, G.4    Asfar, S.5    Dashti, H.6    Romero, P.7    Dashti, A.8    Behbehani, A.9
  • 32
    • 0032927872 scopus 로고    scopus 로고
    • RING1 interacts with multiple polycomb-group proteins and displays tumorigenic activity
    • Satijn DPE, Otte AP (1999) RING1 interacts with multiple polycomb-group proteins and displays tumorigenic activity. Mol Cell Biol 19: 57-68
    • (1999) Mol Cell Biol , vol.19 , pp. 57-68
    • Satijn, D.P.E.1    Otte, A.P.2
  • 33
    • 0035451392 scopus 로고    scopus 로고
    • From cancer genomics to cancer immunotherapy: Toward second-generation tumor antigens
    • Schultze JL, Vonderheide RH (2001) From cancer genomics to cancer immunotherapy: toward second-generation tumor antigens. Trends Immunol 22: 516-523
    • (2001) Trends Immunol , vol.22 , pp. 516-523
    • Schultze, J.L.1    Vonderheide, R.H.2
  • 34
    • 0038002683 scopus 로고    scopus 로고
    • The EZH2 polycomb transcriptional repressor - A marker or mover of metastatic prostate cancer?
    • Sellers WR, Loda M (2002) The EZH2 polycomb transcriptional repressor - a marker or mover of metastatic prostate cancer? Cancer Cell 2: 349-350
    • (2002) Cancer Cell , vol.2 , pp. 349-350
    • Sellers, W.R.1    Loda, M.2
  • 38
    • 0036631492 scopus 로고    scopus 로고
    • Identification of tumour-associated T-cell epitopes for vaccine development
    • Stevanovic S (2002) Identification of tumour-associated T-cell epitopes for vaccine development. Nat Rev Cancer 2: 514-520
    • (2002) Nat Rev Cancer , vol.2 , pp. 514-520
    • Stevanovic, S.1
  • 43
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo EY, Chu CS, Goletz TJ, Schlienger K, Yeh H, Coukos G, Rubin SC, Kaiser LR, June CH (2001) Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res 61: 4766-4772
    • (2001) Cancer Res , vol.61 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3    Schlienger, K.4    Yeh, H.5    Coukos, G.6    Rubin, S.C.7    Kaiser, L.R.8    June, C.H.9
  • 44
    • 0036569127 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
    • Woo EY, Yeh H, Chu CS, Schlienger K, Carroll RG, Riley JL, Kaiser LR, June CH (2002) Cutting edge: regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 168: 4272-4276
    • (2002) J Immunol , vol.168 , pp. 4272-4276
    • Woo, E.Y.1    Yeh, H.2    Chu, C.S.3    Schlienger, K.4    Carroll, R.G.5    Riley, J.L.6    Kaiser, L.R.7    June, C.H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.