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Volumn 41, Issue 5, 2006, Pages 868-875

Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart

Author keywords

Acetate; Acetyl CoA; Acetyl CoA synthetase; Coenzyme A trapping; Compartmentation; Fatty acid oxidation; Isotopomer analysis; Malonyl CoA; Stable isotopes

Indexed keywords

ACETIC ACID; ACETYL COENZYME A; BUFFER; CITRIC ACID; GLUCOSE; LACTIC ACID; LONG CHAIN FATTY ACID; MALONYL COENZYME A; OLEIC ACID; PROPIONIC ACID; PYRUVIC ACID; SHORT CHAIN FATTY ACID;

EID: 33750352789     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2006.08.011     Document Type: Article
Times cited : (9)

References (44)
  • 1
    • 0023654865 scopus 로고
    • Production of acetone and conversion of acetone to acetate in the perfused rat liver
    • Gavino V.C., Somma J., Philbert L., David F., Garneau M., Belair J., et al. Production of acetone and conversion of acetone to acetate in the perfused rat liver. J. Biol. Chem. 262 (1987) 6735-6740
    • (1987) J. Biol. Chem. , vol.262 , pp. 6735-6740
    • Gavino, V.C.1    Somma, J.2    Philbert, L.3    David, F.4    Garneau, M.5    Belair, J.6
  • 2
    • 0021440343 scopus 로고
    • Nonenzymatic decarboxylation of pyruvate
    • Constantopoulos G., and Barranger J.A. Nonenzymatic decarboxylation of pyruvate. Anal. Biochem. 139 (1984) 353-358
    • (1984) Anal. Biochem. , vol.139 , pp. 353-358
    • Constantopoulos, G.1    Barranger, J.A.2
  • 3
    • 0017699890 scopus 로고
    • Origins of blood acetate in the rat
    • Buckley B.M., and Williamson D.H. Origins of blood acetate in the rat. Biochem. J. 166 (1977) 539-545
    • (1977) Biochem. J. , vol.166 , pp. 539-545
    • Buckley, B.M.1    Williamson, D.H.2
  • 4
    • 0024458576 scopus 로고
    • The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects
    • Akanji A.O., Humphreys S., Thursfield V., and Hockaday T.D. The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects. Clin. Chim. Acta 185 (1989) 25-34
    • (1989) Clin. Chim. Acta , vol.185 , pp. 25-34
    • Akanji, A.O.1    Humphreys, S.2    Thursfield, V.3    Hockaday, T.D.4
  • 5
    • 0017686925 scopus 로고
    • Metabolic consequences of high mass-transfer hemodialysis
    • Tolchin N., Roberts J.L., Hayashi J., and Lewis E.J. Metabolic consequences of high mass-transfer hemodialysis. Kidney Int. 11 (1977) 366-378
    • (1977) Kidney Int. , vol.11 , pp. 366-378
    • Tolchin, N.1    Roberts, J.L.2    Hayashi, J.3    Lewis, E.J.4
  • 7
    • 0032716189 scopus 로고    scopus 로고
    • De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
    • Siler S.Q., Neese R.A., and Hellerstein M.K. De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption. Am. J. Clin. Nutr. 70 (1999) 928-936
    • (1999) Am. J. Clin. Nutr. , vol.70 , pp. 928-936
    • Siler, S.Q.1    Neese, R.A.2    Hellerstein, M.K.3
  • 8
    • 0000986283 scopus 로고
    • Alcohol hypoglycemia: I. carbohydrate metabolism of patients with clinical alcohol hypoglycemia and the experimental reproduction of the syndrome with pure ethanol
    • Freinkel N., Singer D.L., Arky R.A., Bleicher S.J., Anderson J.B., and Silbert C.K. Alcohol hypoglycemia: I. carbohydrate metabolism of patients with clinical alcohol hypoglycemia and the experimental reproduction of the syndrome with pure ethanol. J. Clin. Invest. 42 (1963) 1112-1133
    • (1963) J. Clin. Invest. , vol.42 , pp. 1112-1133
    • Freinkel, N.1    Singer, D.L.2    Arky, R.A.3    Bleicher, S.J.4    Anderson, J.B.5    Silbert, C.K.6
  • 9
    • 0032730676 scopus 로고    scopus 로고
    • Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation
    • Goodwin G.W., and Taegtmeyer H. Regulation of fatty acid oxidation of the heart by MCD and ACC during contractile stimulation. Am. J. Physiol. 277 (1999) E772-E777
    • (1999) Am. J. Physiol. , vol.277
    • Goodwin, G.W.1    Taegtmeyer, H.2
  • 10
    • 21244492310 scopus 로고    scopus 로고
    • Myocardial substrate metabolism in the normal and failing heart
    • Stanley W.C., Recchia F.A., and Lopaschuk G.D. Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 85 (2005) 1093-1129
    • (2005) Physiol. Rev. , vol.85 , pp. 1093-1129
    • Stanley, W.C.1    Recchia, F.A.2    Lopaschuk, G.D.3
  • 12
    • 0036285606 scopus 로고    scopus 로고
    • Energy metabolism in the normal and failing heart: potential for therapeutic interventions
    • Stanley W.C., and Chandler M.P. Energy metabolism in the normal and failing heart: potential for therapeutic interventions. Heart Fail Rev. 7 (2002) 115-130
    • (2002) Heart Fail Rev. , vol.7 , pp. 115-130
    • Stanley, W.C.1    Chandler, M.P.2
  • 13
    • 0018862072 scopus 로고
    • Utilization of energy-providing substrates in the isolated working rat heart
    • Taegtmeyer H., Hems R., and Krebs H.A. Utilization of energy-providing substrates in the isolated working rat heart. Biochem. J. 186 (1980) 701-711
    • (1980) Biochem. J. , vol.186 , pp. 701-711
    • Taegtmeyer, H.1    Hems, R.2    Krebs, H.A.3
  • 14
    • 0014787834 scopus 로고
    • Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart
    • Randle P.J., England P.J., and Denton R.M. Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart. Biochem. J. 117 (1970) 677-695
    • (1970) Biochem. J. , vol.117 , pp. 677-695
    • Randle, P.J.1    England, P.J.2    Denton, R.M.3
  • 15
    • 0013947755 scopus 로고
    • 14C metabolism and the effect of acetate on glucose and palmitate metabolism in the perfused rat heart
    • 14C metabolism and the effect of acetate on glucose and palmitate metabolism in the perfused rat heart. Metabolism 15 (1966) 847-855
    • (1966) Metabolism , vol.15 , pp. 847-855
    • Bethencourt, A.V.1    Matos, O.E.2    Shipp, J.C.3
  • 16
    • 0036216076 scopus 로고    scopus 로고
    • Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart
    • O'donnell J.M., Alpert N.M., White L.T., and Lewandowski E.D. Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. Biophys. J. 82 (2002) 11-18
    • (2002) Biophys. J. , vol.82 , pp. 11-18
    • O'donnell, J.M.1    Alpert, N.M.2    White, L.T.3    Lewandowski, E.D.4
  • 17
    • 2442529799 scopus 로고    scopus 로고
    • Peroxisomal fatty acid oxidation is a substantial source of the acetyl moiety of malonyl-CoA in rat heart
    • Reszko A.E., Kasumov T., David F., Jobbins K.A., Thomas K.R., Hoppel C.L., et al. Peroxisomal fatty acid oxidation is a substantial source of the acetyl moiety of malonyl-CoA in rat heart. J. Biol. Chem. 279 (2004) 19574-19579
    • (2004) J. Biol. Chem. , vol.279 , pp. 19574-19579
    • Reszko, A.E.1    Kasumov, T.2    David, F.3    Jobbins, K.A.4    Thomas, K.R.5    Hoppel, C.L.6
  • 18
    • 0018786278 scopus 로고
    • Identification of ATP citrate lyase as a phosphoprotein
    • Linn T.C., and Srere P.A. Identification of ATP citrate lyase as a phosphoprotein. J. Biol. Chem. 254 (1979) 1691-1698
    • (1979) J. Biol. Chem. , vol.254 , pp. 1691-1698
    • Linn, T.C.1    Srere, P.A.2
  • 20
    • 0015381299 scopus 로고
    • Supply and utilization of acetate in mammals
    • Ballard F.J. Supply and utilization of acetate in mammals. Am. J. Clin. Nutr. 25 (1972) 773-779
    • (1972) Am. J. Clin. Nutr. , vol.25 , pp. 773-779
    • Ballard, F.J.1
  • 21
    • 0035815751 scopus 로고    scopus 로고
    • Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate
    • Fujino T., Kondo J., Ishikawa M., Morikawa K., and Yamamoto T.T. Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate. J. Biol. Chem. 276 (2001) 11420-11426
    • (2001) J. Biol. Chem. , vol.276 , pp. 11420-11426
    • Fujino, T.1    Kondo, J.2    Ishikawa, M.3    Morikawa, K.4    Yamamoto, T.T.5
  • 22
    • 0032128015 scopus 로고    scopus 로고
    • Carnitine acetyltransferase is not a cytosolic enzyme in rat heart and therefore cannot function in the energy-linked regulation of cardiac fatty acid oxidation
    • Abbas A.S., Wu G., and Schulz H. Carnitine acetyltransferase is not a cytosolic enzyme in rat heart and therefore cannot function in the energy-linked regulation of cardiac fatty acid oxidation. J. Mol. Cell. Cardiol. 30 (1998) 1305-1309
    • (1998) J. Mol. Cell. Cardiol. , vol.30 , pp. 1305-1309
    • Abbas, A.S.1    Wu, G.2    Schulz, H.3
  • 23
    • 4444311812 scopus 로고    scopus 로고
    • Carnitine acyltransferases and their influence on CoA pools in health and disease
    • Ramsay R.R., and Zammit V.A. Carnitine acyltransferases and their influence on CoA pools in health and disease. Mol. Aspects Med. 25 (2004) 475-493
    • (2004) Mol. Aspects Med. , vol.25 , pp. 475-493
    • Ramsay, R.R.1    Zammit, V.A.2
  • 24
    • 0030662714 scopus 로고    scopus 로고
    • Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system
    • Verleur N., Hettema E.H., Van Roermund C.W., Tabak H.F., and Wanders R.J. Transport of activated fatty acids by the peroxisomal ATP-binding-cassette transporter Pxa2 in a semi-intact yeast cell system. Eur. J. Biochem. 249 (1997) 657-661
    • (1997) Eur. J. Biochem. , vol.249 , pp. 657-661
    • Verleur, N.1    Hettema, E.H.2    Van Roermund, C.W.3    Tabak, H.F.4    Wanders, R.J.5
  • 25
    • 0016440795 scopus 로고
    • The activation of short-chain fatty acids by the soluble fraction of guinea-pig heart and liver mitochondria. The search for a distinct propionyl-CoA synthetase
    • Groot P.H. The activation of short-chain fatty acids by the soluble fraction of guinea-pig heart and liver mitochondria. The search for a distinct propionyl-CoA synthetase. Biochim. Biophys. Acta 380 (1975) 12-20
    • (1975) Biochim. Biophys. Acta , vol.380 , pp. 12-20
    • Groot, P.H.1
  • 26
    • 0019143377 scopus 로고
    • Regulation of thiolases from pig heart. Control of fatty acid oxidation in heart
    • Olowe Y., and Schulz H. Regulation of thiolases from pig heart. Control of fatty acid oxidation in heart. Eur. J. Biochem. 109 (1980) 425-429
    • (1980) Eur. J. Biochem. , vol.109 , pp. 425-429
    • Olowe, Y.1    Schulz, H.2
  • 27
    • 0019841899 scopus 로고
    • Assay of short-chain acyl coenzyme A intermediates in tissue extracts by high-pressure liquid chromatography
    • Corkey B.E., Brandt M., Williams R.J., and Williamson J.R. Assay of short-chain acyl coenzyme A intermediates in tissue extracts by high-pressure liquid chromatography. Anal. Biochem. 118 (1981) 30-41
    • (1981) Anal. Biochem. , vol.118 , pp. 30-41
    • Corkey, B.E.1    Brandt, M.2    Williams, R.J.3    Williamson, J.R.4
  • 28
    • 0021224619 scopus 로고
    • Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart
    • Sundqvist K.E., Peuhkurinen K.J., Hiltunen J.K., and Hassinen I.E. Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. Biochim. Biophys. Acta 801 (1984) 429-436
    • (1984) Biochim. Biophys. Acta , vol.801 , pp. 429-436
    • Sundqvist, K.E.1    Peuhkurinen, K.J.2    Hiltunen, J.K.3    Hassinen, I.E.4
  • 29
    • 33750815237 scopus 로고    scopus 로고
    • Anaplerotic effects of propionate on oxidations of acetate and long-chain fatty acids
    • Liedtke A.J., Hacker T., Renstrom B., and Nellis S.H. Anaplerotic effects of propionate on oxidations of acetate and long-chain fatty acids. Am. J. Physiol. 270 (1996) H2197-H2203
    • (1996) Am. J. Physiol. , vol.270
    • Liedtke, A.J.1    Hacker, T.2    Renstrom, B.3    Nellis, S.H.4
  • 30
    • 0016438089 scopus 로고
    • Regulation of long chain fatty acid activation in heart muscle
    • Oram J.F., Wenger J.I., and Neely J.R. Regulation of long chain fatty acid activation in heart muscle. J. Biol. Chem. 250 (1975) 73-78
    • (1975) J. Biol. Chem. , vol.250 , pp. 73-78
    • Oram, J.F.1    Wenger, J.I.2    Neely, J.R.3
  • 32
    • 0027375410 scopus 로고
    • Comparison of the active sites of the purified carnitine acyltransferases from peroxisomes and mitochondria by using a reaction-intermediate analogue
    • Bhaird N.NA., Kumaravel G., Gandour R.D., Krueger M.J., and Ramsay R.R. Comparison of the active sites of the purified carnitine acyltransferases from peroxisomes and mitochondria by using a reaction-intermediate analogue. Biochem. J. 294 (1993) 645-651
    • (1993) Biochem. J. , vol.294 , pp. 645-651
    • Bhaird, N.NA.1    Kumaravel, G.2    Gandour, R.D.3    Krueger, M.J.4    Ramsay, R.R.5
  • 33
    • 0029072758 scopus 로고
    • Eicosapentaenoic acid causes transient accumulation of lipids in rat myocardium
    • Hexeberg S., Willumsen N., and Berge R.K. Eicosapentaenoic acid causes transient accumulation of lipids in rat myocardium. Biochim. Biophys. Acta 1256 (1995) 341-345
    • (1995) Biochim. Biophys. Acta , vol.1256 , pp. 341-345
    • Hexeberg, S.1    Willumsen, N.2    Berge, R.K.3
  • 34
    • 0026518929 scopus 로고
    • Coenzyme A sequestration in rat hearts oxidizing ketone bodies
    • Russell III R.R., and Taegtmeyer H. Coenzyme A sequestration in rat hearts oxidizing ketone bodies. J. Clin. Invest. 89 (1992) 968-973
    • (1992) J. Clin. Invest. , vol.89 , pp. 968-973
    • Russell III, R.R.1    Taegtmeyer, H.2
  • 35
    • 0026065784 scopus 로고
    • Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate
    • Russell III R.R., and Taegtmeyer H. Changes in citric acid cycle flux and anaplerosis antedate the functional decline in isolated rat hearts utilizing acetoacetate. J. Clin. Invest. 87 (1991) 384-390
    • (1991) J. Clin. Invest. , vol.87 , pp. 384-390
    • Russell III, R.R.1    Taegtmeyer, H.2
  • 37
    • 0029075379 scopus 로고
    • Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity
    • Krahenbuhl S., Mang G., Kupferschmidt H., Meier P.J., and Krause M. Plasma and hepatic carnitine and coenzyme A pools in a patient with fatal, valproate induced hepatotoxicity. Gut 37 (1995) 140-143
    • (1995) Gut , vol.37 , pp. 140-143
    • Krahenbuhl, S.1    Mang, G.2    Kupferschmidt, H.3    Meier, P.J.4    Krause, M.5
  • 38
    • 0037086594 scopus 로고    scopus 로고
    • Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase
    • Silva M.F., Ruiter J.P., Overmars H., Bootsma A.H., van Gennip A.H., Jakobs C., et al. Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase. Biochem. J. 362 (2002) 755-760
    • (2002) Biochem. J. , vol.362 , pp. 755-760
    • Silva, M.F.1    Ruiter, J.P.2    Overmars, H.3    Bootsma, A.H.4    van Gennip, A.H.5    Jakobs, C.6
  • 40
    • 0036216076 scopus 로고    scopus 로고
    • Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart
    • O'donnell J.M., Alpert N.M., White L.T., and Lewandowski E.D. Coupling of mitochondrial fatty acid uptake to oxidative flux in the intact heart. Biophys. J. 82 (2002) 11-18
    • (2002) Biophys. J. , vol.82 , pp. 11-18
    • O'donnell, J.M.1    Alpert, N.M.2    White, L.T.3    Lewandowski, E.D.4
  • 41
    • 0015212004 scopus 로고
    • The subcellular distribution of short-chain fatty acyl-CoA synthetase activity in rat tissues
    • Barth C., Sladek M., and Decker K. The subcellular distribution of short-chain fatty acyl-CoA synthetase activity in rat tissues. Biochim. Biophys. Acta 248 (1971) 24-33
    • (1971) Biochim. Biophys. Acta , vol.248 , pp. 24-33
    • Barth, C.1    Sladek, M.2    Decker, K.3
  • 42
    • 0015525537 scopus 로고
    • Dietary changes of cytoplasmic acetyl-CoA synthetase in different rat tissues
    • Barth C., Sladek M., and Decker K. Dietary changes of cytoplasmic acetyl-CoA synthetase in different rat tissues. Biochim. Biophys. Acta 260 (1972) 1-9
    • (1972) Biochim. Biophys. Acta , vol.260 , pp. 1-9
    • Barth, C.1    Sladek, M.2    Decker, K.3
  • 43
    • 0016827869 scopus 로고
    • Organ and intracellular localization of short-chain acyl-CoA synthetases in rat and guinea-pig
    • Scholte H.R., and Groot P.H. Organ and intracellular localization of short-chain acyl-CoA synthetases in rat and guinea-pig. Biochim. Biophys. Acta 409 (1975) 283-296
    • (1975) Biochim. Biophys. Acta , vol.409 , pp. 283-296
    • Scholte, H.R.1    Groot, P.H.2
  • 44
    • 33645753553 scopus 로고    scopus 로고
    • Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts
    • Gambert S., Vergely C., Filomenko R., Moreau D., Bettaieb A., Opie L.H., et al. Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts. Mol. Cell. Biochem. 283 (2006) 147-152
    • (2006) Mol. Cell. Biochem. , vol.283 , pp. 147-152
    • Gambert, S.1    Vergely, C.2    Filomenko, R.3    Moreau, D.4    Bettaieb, A.5    Opie, L.H.6


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