메뉴 건너뛰기




Volumn 351, Issue 1, 2006, Pages 253-258

The interaction of hepatitis B virus X protein and protein phosphatase type 2 Cα and its effect on IL-6

Author keywords

HBx; Hepatocellular carcinoma; IL 6; PP2C

Indexed keywords

ENZYME; HEPATITIS B VIRUS X PROTEIN; INTERLEUKIN 6; PHOSPHOPROTEIN PHOSPHATASE 2 CALPHA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 33750316808     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.10.028     Document Type: Article
Times cited : (20)

References (24)
  • 1
    • 0030200222 scopus 로고    scopus 로고
    • Hepatitis B virus-induced hepatocellular carcinoma: possible roles for HBx
    • Cromlish J.A. Hepatitis B virus-induced hepatocellular carcinoma: possible roles for HBx. Trends Microbiol. 4 (1996) 270-274
    • (1996) Trends Microbiol. , vol.4 , pp. 270-274
    • Cromlish, J.A.1
  • 2
    • 0030041821 scopus 로고    scopus 로고
    • Hepadnaviral X protein: review of recent progress
    • Yen T.S. Hepadnaviral X protein: review of recent progress. J. Biomed. Sci. 3 (1996) 20-30
    • (1996) J. Biomed. Sci. , vol.3 , pp. 20-30
    • Yen, T.S.1
  • 3
    • 0034954277 scopus 로고    scopus 로고
    • X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis
    • Diao J., Garces R., and Richardson C.D. X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis. Cytokine Growth Factor Rev. 12 (2001) 189-205
    • (2001) Cytokine Growth Factor Rev. , vol.12 , pp. 189-205
    • Diao, J.1    Garces, R.2    Richardson, C.D.3
  • 4
    • 0031898616 scopus 로고    scopus 로고
    • Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas
    • Su Q., Schroder C.H., Hofmann W.J., Otto G., Pichlmayr R., and Bannasch P. Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas. Hepatology 27 (1998) 1109-1120
    • (1998) Hepatology , vol.27 , pp. 1109-1120
    • Su, Q.1    Schroder, C.H.2    Hofmann, W.J.3    Otto, G.4    Pichlmayr, R.5    Bannasch, P.6
  • 5
    • 0026474748 scopus 로고
    • Regulation of IL6 gene expression
    • Sehgal P.B. Regulation of IL6 gene expression. Res. Immunol. 143 (1992) 724-734
    • (1992) Res. Immunol. , vol.143 , pp. 724-734
    • Sehgal, P.B.1
  • 6
    • 3042575159 scopus 로고    scopus 로고
    • Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions
    • Coskun U., Bukan N., Sancak B., Gunel N., Ozenirler S., Unal A., and Yucel A. Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions. Neoplasma 51 (2004) 209-213
    • (2004) Neoplasma , vol.51 , pp. 209-213
    • Coskun, U.1    Bukan, N.2    Sancak, B.3    Gunel, N.4    Ozenirler, S.5    Unal, A.6    Yucel, A.7
  • 7
    • 0031746396 scopus 로고    scopus 로고
    • Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells
    • Lee Y., Park U.S., Choi I., Yoon S.K., Park Y.M., and Lee Y.I. Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells. Clin. Cancer Res. 4 (1998) 1711-1717
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1711-1717
    • Lee, Y.1    Park, U.S.2    Choi, I.3    Yoon, S.K.4    Park, Y.M.5    Lee, Y.I.6
  • 8
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T., Ishihara K., and Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 19 (2000) 2548-2556
    • (2000) Oncogene , vol.19 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 9
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
    • Waris G., Huh K.W., and Siddiqui A. Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol. Cell Biol. 21 (2001) 7721-7730
    • (2001) Mol. Cell Biol. , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 10
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • Cohen P. The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58 (1989) 453-508
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 453-508
    • Cohen, P.1
  • 11
    • 0037515747 scopus 로고    scopus 로고
    • Cell cycle regulation and p53 activation by protein phosphatase 2C alpha
    • Ofek P., Ben-Meir D., Kariv-Inbal Z., Oren M., and Lavi S. Cell cycle regulation and p53 activation by protein phosphatase 2C alpha. J. Biol. Chem. 278 (2003) 14299-14305
    • (2003) J. Biol. Chem. , vol.278 , pp. 14299-14305
    • Ofek, P.1    Ben-Meir, D.2    Kariv-Inbal, Z.3    Oren, M.4    Lavi, S.5
  • 12
    • 0028942656 scopus 로고
    • Requirement of serine phosphorylation for formation of STAT-promoter complexes
    • Zhang X., Blenis J., Li H.C., Schindler C., and Chen-Kiang S. Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267 (1995) 1990-1994
    • (1995) Science , vol.267 , pp. 1990-1994
    • Zhang, X.1    Blenis, J.2    Li, H.C.3    Schindler, C.4    Chen-Kiang, S.5
  • 13
    • 7644221446 scopus 로고    scopus 로고
    • Phosphatase inhibition potentiates IL-6 production by mast cells in response to FcepsilonRI-mediated activation: involvement of p38 MAPK
    • Boudreau R.T., Hoskin D.W., and Lin T.J. Phosphatase inhibition potentiates IL-6 production by mast cells in response to FcepsilonRI-mediated activation: involvement of p38 MAPK. J. Leukoc. Biol. 76 (2004) 1075-1081
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 1075-1081
    • Boudreau, R.T.1    Hoskin, D.W.2    Lin, T.J.3
  • 14
    • 0034718770 scopus 로고    scopus 로고
    • Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells
    • Yun C., Lee J.H., Park H., Jin Y.M., Park S., Park K., and Cho H. Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells. Oncogene 19 (2000) 5163-5172
    • (2000) Oncogene , vol.19 , pp. 5163-5172
    • Yun, C.1    Lee, J.H.2    Park, H.3    Jin, Y.M.4    Park, S.5    Park, K.6    Cho, H.7
  • 15
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields S., and Song O. A novel genetic system to detect protein-protein interactions. Nature 340 (1989) 245-246
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 16
    • 0031572590 scopus 로고    scopus 로고
    • Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors
    • Kim J., Chwae Y.J., Kim M.Y., Choi I.H., Park J.H., and Kim S.J. Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors. J. Immunol. 159 (1997) 3875-3882
    • (1997) J. Immunol. , vol.159 , pp. 3875-3882
    • Kim, J.1    Chwae, Y.J.2    Kim, M.Y.3    Choi, I.H.4    Park, J.H.5    Kim, S.J.6
  • 17
    • 0025877838 scopus 로고
    • Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatases
    • Takai A., and Mieskes G. Inhibitory effect of okadaic acid on the p-nitrophenyl phosphate phosphatase activity of protein phosphatases. Biochem. J. 275 Pt. 1 (1991) 233-239
    • (1991) Biochem. J. , vol.275 , Issue.PART 1 , pp. 233-239
    • Takai, A.1    Mieskes, G.2
  • 18
    • 9144250174 scopus 로고    scopus 로고
    • Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor gamma through protein-protein interaction
    • Choi Y.H., Kim H.I., Seong J.K., Yu D.Y., Cho H., Lee M.O., Lee J.M., Ahn Y.H., Kim S.J., and Park J.H. Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor gamma through protein-protein interaction. FEBS Lett. 557 (2004) 73-80
    • (2004) FEBS Lett. , vol.557 , pp. 73-80
    • Choi, Y.H.1    Kim, H.I.2    Seong, J.K.3    Yu, D.Y.4    Cho, H.5    Lee, M.O.6    Lee, J.M.7    Ahn, Y.H.8    Kim, S.J.9    Park, J.H.10
  • 19
    • 32244445762 scopus 로고    scopus 로고
    • Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells
    • Chan D.W., and Ng I.O. Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells. J. Pathol. 208 (2006) 372-380
    • (2006) J. Pathol. , vol.208 , pp. 372-380
    • Chan, D.W.1    Ng, I.O.2
  • 20
    • 0027462253 scopus 로고
    • Interleukin 6 production by peripheral blood mononuclear cells in patients with chronic hepatitis B virus infection and primary biliary cirrhosis
    • Kakumu S., Shinagawa T., Ishikawa T., Yoshioka K., Wakita T., and Ida N. Interleukin 6 production by peripheral blood mononuclear cells in patients with chronic hepatitis B virus infection and primary biliary cirrhosis. Gastroenterol. Jpn. 28 (1993) 18-24
    • (1993) Gastroenterol. Jpn. , vol.28 , pp. 18-24
    • Kakumu, S.1    Shinagawa, T.2    Ishikawa, T.3    Yoshioka, K.4    Wakita, T.5    Ida, N.6
  • 23
    • 0036063636 scopus 로고    scopus 로고
    • Relationship between protein phosphatase type-2C activity and induction of apoptosis in cultured neuronal cells
    • Klumpp S., Selke D., Ahlemeyer B., Schaper C., and Krieglstein J. Relationship between protein phosphatase type-2C activity and induction of apoptosis in cultured neuronal cells. Neurochem. Int. 41 (2002) 251-259
    • (2002) Neurochem. Int. , vol.41 , pp. 251-259
    • Klumpp, S.1    Selke, D.2    Ahlemeyer, B.3    Schaper, C.4    Krieglstein, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.