Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock

Critical Care Medicine

Volumn 34, Issue 11, 2006, Pages 2719-2728

  Kalil, Andre C ^b   Sevransky, Jonathan E ^c   Myers, Daniela E ^a   Esposito, Claire ^a   Vandivier, R William ^d   Eichacker, Peter ^a   Susla, Greg M ^a   Solomon, Steven B ^a   Csako, Gyorgy ^a   Costello, Rene ^a   Sittler, Kelly J ^a   Banks, Steve ^a   Natanson, Charles ^a   Danner, Robert L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Immunonutrition; L arginine; N acetylcysteine; Nitric oxide; Sepsis

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; ARGININE; BICARBONATE; CREATININE; LIVER ENZYME; NITRATE; NITRITE; ORNITHINE; PEROXYNITRITE; PLACEBO;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PH; ARTICLE; BICARBONATE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE EXACERBATION; DOG; DRUG MEGADOSE; ENTEROBACTER INFECTION; ENZYME BLOOD LEVEL; ESCHERICHIA COLI; EXPERIMENTAL MODEL; HEMODYNAMICS; LABORATORY TEST; LOW DRUG DOSE; MEAN ARTERIAL PRESSURE; MONOTHERAPY; MORTALITY; NONHUMAN; ORGAN INJURY; PERITONITIS; PRIORITY JOURNAL; RANDOMIZATION; SEPTIC SHOCK; SURVIVAL; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL;

ACETYLCYSTEINE; ANIMALS; ARGININE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FREE RADICAL SCAVENGERS; IMMUNOTHERAPY; NITRIC OXIDE; PARENTERAL NUTRITION; PROPORTIONAL HAZARDS MODELS; RANDOM ALLOCATION; SHOCK, SEPTIC; SURVIVAL ANALYSIS;

EID: 33750237725     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000242757.26245.03     Document Type: Article

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