Inhibition of CD1d1-mediated antigen presentation by the vaccinia virus B1R and H5R molecules

European Journal of Immunology

Volumn 36, Issue 10, 2006, Pages 2595-2600

  Webb, Tonja J Roberts ^a,b   Litavecz, Roberta A ^a,b   Khan, Masood A ^a,b   Du, Wenjun ^c   Gervay Hague, Jacquelyn ^c   Renukaradhya, Gourapura J ^a,b   Brutkiewicz, Randy R ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WALTHER CANCER INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antigen presentation; CD1d; Immune evasion; NKT cells; Vaccinia virus

Indexed keywords

CD1D ANTIGEN; CD1D1 ANTIGEN; LIVE VACCINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE; SMALLPOX VACCINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVATION; IMMUNOREGULATION; INNATE IMMUNITY; MUTATIONAL ANALYSIS; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; SMALLPOX; T LYMPHOCYTE SUBPOPULATION; VACCINATION; VACCINIA VIRUS; VIRUS CELL INTERACTION; VIRUS IMMUNITY; VIRUS INFECTION;

EID: 33750227454     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200636024     Document Type: Article

References (34)

1. Watts, C., Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 1997. 15: 821-850.
2. Yewdell, J. W., Schubert, U. and Bennink, J. R., At the crossroads of cell biology and immunology: DRiPs and other sources of peptide ligands for MHC class I molecules. J. Cell Sci. 2001. 114: 845-851.
3. Brutkiewicz, R. R., Lin, Y., Cho, S., Hwang, Y. K., Sriram, V. and Roberts, T. J., CD1d-mediated antigen presentation to natural killer T (NKT) cells. Crit. Rev. Immunol. 2003. 23: 403-419.
4. Jayawardena-Wolf, J., Benlagha, K., Chiu, Y. H., Mehr, R. and Bendelac, A., CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 2001. 15: 897-908.
5. Kang, S. J. and Cresswell, P., Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 2002. 21: 1650-1660.
6. Kronenberg, M. and Gapin, L., The unconventional lifestyle of NKT Cells. Nat. Rev. Immunol. 2002. 2: 557-568.
7. Taniguchi, M., Harada, M., Kojo, S., Nakayama, T. and Wakao, H., The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 2003. 21: 483-513.
8. Moss, B., Regulation of vaccinia virus transcription. Annu. Rev. Biochem. 1990. 59: 661-688.
9. Buller, R. M. and Palumbo, G. J., Poxvirus pathogenesis. Microbiol. Rev. 1991. 55: 80-122.
10. Seet, B. T., Johnston, J. B., Brunetti, C. R., Barrett, J. W., Everett, H., Cameron, C., Sypula, J. et al., Poxviruses and immune evasion. Annu. Rev. Immunol. 2003. 21: 377-423.
11. Renukaradhya, G. J., Roberts Webb, T. J., Khan, M. A., Lin, Y. L., Du, W., Gervay-Hague, J. and Brutkiewicz, R. R., Virus-induced inhibition of CD1d1-mediated antigen presentation: reciprocal regulation by p38 and ERK J. Immunol. 2005. 175: 4301-4308.
12. Beaud, G. and Beaud, R., Temperature-dependent phosphorylation state of the H5R protein synthesised at the early stage of infection in cells infected with vaccinia virus ts mutants of the B1R and F10L protein kinases. Intervirology 2000. 43: 67-70.
13. Brown, N. G., Morrice, N., Beaud, G., Hardie, G. and Leader, D. P., Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R. BMC Biochem. 2000. 1: 2-6.
14. Beaud, G., Beaud, R. and Leader, D. P., Vaccinia virus gene H5R encodes a protein that is phosphorylated by the multisubstrate vaccinia virus B1R protein kinase. J. Virol. 1995. 69: 1819-1826.
15. Banham, A. H. and Smith, G. L, Vaccinia virus gene B1R encodes a 34-kDa serine/threonine protein kinase that localizes in cytoplasmic factories and is packaged into virions. Virology 1992. 191: 803-812.
16. Lin, S., Chen, W. and Broyles, S. S., The vaccinia virus B1R gene product is a serine/threonine protein kinase. J. Virol. 1992. 66: 2717-2723.
17. Condit, R. C. and Motyczka, A., Isolation and preliminary characterization of temperature-sensitive mutants of vaccinia virus. Virology 1981. 113: 224-241.
18. Condit, R. C., Motyczka, A. and Spizz, G., Isolation, characterization, and physical mapping of temperature-sensitive mutants of vaccinia virus. Virology 1983. 128: 429-443.
19. Rempel, R. E. and Traktman, P., Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins. J. Virol. 1992. 66: 4413-4426.
20. Banham, A. H., Leader, D. P. and Smith, G. L., Phosphorylation of ribosomal proteins by the vaccinia virus B1R protein kinase. FEBS Lett. 1993. 321: 27-31.
21. Kovacs, G. R. and Moss, B., The vaccinia virus H5R gene encodes late gene transcription factor 4: purification, cloning, and overexpression. J. Virol. 1996. 70: 6796-6802.
22. DeMasi J. and Traktman, P., Clustered charge-to-alanine muragenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesis. J. Virol. 2000. 74: 2393-2405.
23. Roberts, T. J., Sriram, V., Spence, P. M., Gui, M., Hayakawa, K., Bacik, L., Bennink, J. R. et al., Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells. J. Immunol. 2002. 168: 5409-5414.
24. Traktman, P., Anderson, M. K. and Rempel, R. E., Vaccinia virus encodes an essential gene with strong homology to protein kinases. J. Biol. Chem. 1989. 264: 21458-21461.
25. Howard, S. T. and Smith, G. L., Two early vaccinia virus genes encode polypeptides related to protein kinases. J. Gen. Virol. 1989. 70: 3187-3201.
26. Shchelkunov, S. N., Blinov, V. M., Resenchuk, S. M., Totmenin, A. V., Olenina, L. V., Chirikova, G. B. and Sandakhchiev, L. S., Analysis of the nucleotide sequence of 53 kbp from the right terminus of the genome of variola major virus strain India-1967. Virus Res. 1994. 34: 207-236.
27. Shchelkunov, S. N., Totmenin, A. V., Babkin, I. V., Safronov, P. F., Ryazankina, O. I., Petrov, N. A., Gutorov, V. V. et al., Human monkeypox and smallpox viruses: genomic comparison. FEBS Lett. 2001. 509: 66-70.
28. Goebel, S. J., Johnson, G. P., Perkus, M. E., Davis, S. W., Winslow, J. P. and Paoletti, E., The complete DNA sequence of vaccinia virus. Virology 1990. 179: 247-266, 517-263.
29. Tortorella, D., Gewurz, B. E., Furman, M. H., Schust, D. J. and Ploegh, H. L., Viral subversion of the immune system. Annu. Rev. Immunol. 2000. 18: 861-926.
30. + T cells produce large amounts of IL-4 and IFN-γ upon activation by anti-CD3 or CD1. J. Immunol. 1997. 159: 2240-2249.
31. + NK T lymphocytes. J. Immunol. 1998. 161: 3271-3281.
32. Yuwen, H., Cox, J. H., Yewdell, J. W., Bennink, J. R. and Moss, B., Nuclear localization of a double-stranded RNA-binding protein encoded by the vaccinia virus E3L gene. Virology 1993. 195: 732-744.
33. Ishii, K. and Moss, B., Mapping interaction sites of the A20R protein component of the vaccinia virus DNA replication complex. Virology 2002. 303: 232-239.
34. Hobbs, J. A., Cho, S., Roberts, T. J., Sriram, V., Zhang, J., Xu, M. and Brutkiewicz, R. R., Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus. J. Virol. 2001. 75: 10746-10754.