메뉴 건너뛰기




Volumn 10, Issue 3, 2006, Pages 112-115

RNA intereference: A powerful laboratory tool and its therapeutic implications

Author keywords

Gene silencing; miRNA; RNA interference; siRNA

Indexed keywords

DOUBLE STRANDED RNA; MICRORNA; SMALL INTERFERING RNA;

EID: 33750213249     PISSN: 11084189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (22)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic intereference by double stranded RNA in Caenorhabditis elegans
    • Fire A, Montgomery M K, Kostas S A, Driver S E, and Mello C C. Potent and specific genetic intereference by double stranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Montgomery, M.K.2    Kostas, S.A.3    Driver, S.E.4    Mello, C.C.5
  • 2
    • 0001359591 scopus 로고
    • Indroduction of a Chimeric Chalcone Synthase Gene into Petunia results in reversible co-suppression of homologous genes in trans
    • Napoli C, Lemieux C, and Jorgensen R. Indroduction of a Chimeric Chalcone Synthase Gene into Petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 1990; 2:279-289
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 3
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • Hamilton A and Baulcombe D. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 1999; 286:950-952
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.1    Baulcombe, D.2
  • 5
    • 0035863097 scopus 로고    scopus 로고
    • RNA intereference is mediated by 21- and 22- nucleotide RNAs
    • Elbashir S M, Lendeckel W, Tuschl T. RNA intereference is mediated by 21- and 22- nucleotide RNAs. Genes Dev 2001; 15:188-200
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 6
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA intereference
    • Bernstein E, Caudy AA, Hammond SM, and Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA intereference. Nature 2001; 409:363-366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 7
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirments and small interefering RNA structure in the RNA intereference pathway
    • Nykanen A, Haley B, and Zamore PD. ATP requirments and small interefering RNA structure in the RNA intereference pathway. Cell 2001; 107:309-321
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 8
    • 1842816517 scopus 로고    scopus 로고
    • Dinstinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee YS, Nakara K, Pharm JW, et al. Dinstinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 2004; 117:69-81
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1    Nakara, K.2    Pharm, J.W.3
  • 9
    • 24644481318 scopus 로고    scopus 로고
    • DICER-LIKE 4 functions in trans-acting small interefereng RNA biogenesis and vegetative phase change in Arabidopsis thaliana
    • Xie Z, Allen E, Wilken A, and Carrington JC. DICER-LIKE 4 functions in trans-acting small interefereng RNA biogenesis and vegetative phase change in Arabidopsis thaliana. Proc Natl Acad Sci USA 2005; 102:12984-12989
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12984-12989
    • Xie, Z.1    Allen, E.2    Wilken, A.3    Carrington, J.C.4
  • 10
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNA guide target RNA cleavage in RNAi
    • Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T. Single-stranded antisense siRNA guide target RNA cleavage in RNAi. Cell 2002; 110:563-574
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 11
    • 2442495329 scopus 로고    scopus 로고
    • RISC is a 5′ phosphomonoester-producing RNA endonuclease
    • Martinez J, Tuschl T. RISC is a 5′ phosphomonoester-producing RNA endonuclease. Genes Dev 2004; 18:975-980
    • (2004) Genes Dev , vol.18 , pp. 975-980
    • Martinez, J.1    Tuschl, T.2
  • 12
  • 13
    • 1642588268 scopus 로고    scopus 로고
    • The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification
    • Cook HA, Koppetsch BS, Wu J, Theurkauf WE. The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell 2004; 116:817-829
    • (2004) Cell , vol.116 , pp. 817-829
    • Cook, H.A.1    Koppetsch, B.S.2    Wu, J.3    Theurkauf, W.E.4
  • 14
    • 1342346710 scopus 로고    scopus 로고
    • A conserved siRNA-degrating RNase negatively regulates RNA intereference in C. elegans
    • Kennedy S, Wang D, Ruvkun G. A conserved siRNA-degrating RNase negatively regulates RNA intereference in C. elegans. Nature 2004; 427:645-649
    • (2004) Nature , vol.427 , pp. 645-649
    • Kennedy, S.1    Wang, D.2    Ruvkun, G.3
  • 15
    • 33750205600 scopus 로고    scopus 로고
    • RNA intereference-2001
    • Sharp PA. RNA intereference-2001. Genes Dev 2001; 10:638-643
    • (2001) Genes Dev , vol.10 , pp. 638-643
    • Sharp, P.A.1
  • 16
    • 0035798399 scopus 로고    scopus 로고
    • RNAi as random degenarative PCR. siRNA primers convert mRNA into dsRNA that are degraded to generate new siRNAs
    • Lipardi C, Wei Q, Paterson BM. RNAi as random degenarative PCR. siRNA primers convert mRNA into dsRNA that are degraded to generate new siRNAs. Cell 2001; 107:297-307
    • (2001) Cell , vol.107 , pp. 297-307
    • Lipardi, C.1    Wei, Q.2    Paterson, B.M.3
  • 17
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomic, biogenesis, mechanism and function
    • Bartel DP. MicroRNAs: genomic, biogenesis, mechanism and function. Cell 2004; 116:281-297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 18
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with big role in gene regulation
    • He L and Hannon GJ. MicroRNAs: small RNAs with big role in gene regulation. Nature Rev. Genet 2004; 5:522-531
    • (2004) Nature Rev Genet , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 19
    • 4944261427 scopus 로고    scopus 로고
    • The silent treatment
    • Clayton J. The silent treatment. Nature 2004; 431:599-605
    • (2004) Nature , vol.431 , pp. 599-605
    • Clayton, J.1
  • 20
    • 0037370498 scopus 로고    scopus 로고
    • A lentilvirus-based system to functionally silence genes in primary mammalian cells, stem cells and trangenic mice by RNA inteference
    • Rubinson DA, Dillon CP, Kwiatkowski AV, et al. A lentilvirus-based system to functionally silence genes in primary mammalian cells, stem cells and trangenic mice by RNA inteference. Nature Genet 2003; 33:401-406
    • (2003) Nature Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 21
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-alpha by short interefering RNA in plasmacytoid dendritic cells through TLR7
    • Hornung V, Guenthner-Biller M, Bourquin C, et al. Sequence-specific potent induction of IFN-alpha by short interefering RNA in plasmacytoid dendritic cells through TLR7. Nat Med 2005; 11:263-270
    • (2005) Nat Med , vol.11 , pp. 263-270
    • Hornung, V.1    Guenthner-Biller, M.2    Bourquin, C.3
  • 22
    • 22344454846 scopus 로고    scopus 로고
    • Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
    • Judge A, Sood V, Shaw J, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat. Biotechnol 2005; 23:457-462
    • (2005) Nat Biotechnol , vol.23 , pp. 457-462
    • Judge, A.1    Sood, V.2    Shaw, J.3    Fang, D.4    McClintock, K.5    MacLachlan, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.