Specific down-regulation of spinal μ-opioid receptor and reduced analgesic effects of morphine in mice with postherpetic pain

European Journal of Pharmacology

Volumn 550, Issue 1-3, 2006, Pages 62-67

  Takasaki, Ichiro ^a   Nojima, Hiroshi ^b   Shiraki, Kimiyasu ^a   Kuraishi, Yasushi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b OHU UNIVERSITY   (Japan)

Author keywords

Analgesia; Herpes zoster; Morphine; Nalfurafine; Opioid receptor; Postherpetic neuralgia

Indexed keywords

ACICLOVIR; KAPPA OPIATE RECEPTOR; MESSENGER RNA; MORPHINE; MU OPIATE RECEPTOR; NALFURAFINE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; DRUG EFFECT; EXPERIMENTAL INFECTION; FEMALE; HERPES VIRUS; HERPES ZOSTER; IMMUNOREACTIVITY; INOCULATION; LUMBAR SPINAL CORD; MOUSE; NONHUMAN; PARALYSIS; PERIPHERAL NEUROPATHY; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; SENSORY NERVE CELL;

ANALGESICS, OPIOID; ANIMALS; DOWN-REGULATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GANGLIA, SPINAL; HERPESVIRUS 1, HUMAN; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; MICE; MICE, INBRED BALB C; MORPHINANS; MORPHINE; NEURALGIA, POSTHERPETIC; PAIN; PAIN MEASUREMENT; POSTERIOR HORN CELLS; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINE; SPIRO COMPOUNDS;

EID: 33750211320     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.08.041     Document Type: Article

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