The effects of apoptotic, deported human placental trophoblast on macrophages: Possible consequences for pregnancy

Journal of Reproductive Immunology

Volumn 72, Issue 1-2, 2006, Pages 33-45

  Abumaree, M H ^a   Stone, P R ^a   Chamley, L W ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Apoptosis; Deportation; IL 1 ; IL 10; Indoleamine 2,3 dioxygenase; Macrophage; Trophoblast

Indexed keywords

CASPASE 3; CYTOCHALASIN B; CYTOKINE; ENZYME; IMMUNOSUPPRESSIVE AGENT; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; INTERLEUKIN 1BETA ANTIBODY; PARAFORMALDEHYDE; TRYPTOPHAN;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL AGING; CELL MIGRATION; CELL STRAIN U937; CHORION VILLUS; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FETUS CELL; HUMAN; HUMAN TISSUE; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INNATE IMMUNITY; MACROPHAGE; MATERNAL BLOOD; MONONUCLEAR CELL; PHAGOCYTOSIS; PLACENTA; PREGNANCY; PRIORITY JOURNAL; SYNCYTIOTROPHOBLAST; TROPHOBLAST;

ANTIGENS, CD45; APOPTOSIS; CYTOCHALASIN B; DIOXYGENASES; FEMALE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-1BETA; MACROPHAGES; PHAGOCYTOSIS; PLACENTA; PREGNANCY; TROPHOBLASTS;

EID: 33750209228     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2006.03.001     Document Type: Article

References (31)

1. Albert M.L., Jegathesan M., and Darnell R.B. Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat. Immunol. 2 (2001) 1010-1017
2. Alvarez H., Benedetti W.L., and De Leonis V.K. Syncytial proliferation in normal and toxemic pregnancies. Obstet. Gynecol. 29 (1967) 637-643
3. Attwood H.D., and Park W.W. Embolism to the lungs by trophoblast. J. Obstet. Gynaecol. Br. Commonw. 68 (1961) 611-617
4. Bardawil W.A., and Toy B.L. The natural history of choriocarcinoma: problems of immunity and spontaneous regression. Ann. N. Y. Acad. Sci. 80 (1959) 197-261
5. Benirschke K., and Kaufmann P. Pathology of the Human Placenta. fourth ed. (2000), Springer, New York
6. Bittencourt M.C., Perruche S., Contassot E., Fresnay S., Baron M.H., Angonin R., Aubin F., Herve P., Tiberghien P., and Saas P. Intravenous injection of apoptotic leukocytes enhances bone marrow engraftment across major histocompatibility barriers. Blood 98 (2001) 224-230
7. Buckingham K.L., Stone P.R., Smith J.F., and Chamley L.W. Antiphospholipid antibodies in serum and follicular fluid-is there a correlation with IVF implantation failure?. Hum. Reprod. 21 3 (2006) 728-734
8. Buelens C., Willems F., Delvaux A., Pierard G., Delville J.P., Velu T., and Goldman M. Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells. Eur. J. Immunol. 25 (1995) 2668-2672
9. Chua S., Wilkins T., Sargent I., and Redman C. Trophoblast deportation in pre-eclamptic pregnancy. Br. J. Obstet. Gynaecol. 98 (1991) 973-979
10. Coelho O.F., and Valeri V. Pulmonary trophoblastic deportation. Cytologic aspects. Acta Cytol. 21 (1977) 338-340
11. Cohle S.D., and Petty C.S. Sudden death caused by embolization of trophoblast from hydatidiform mole. J. Forensic Sci. 30 (1985) 1279-1283
12. de Waal Malefyt R., Haanen J., Spits H., Roncarolo M.G., te Velde A., Figdor C., Johnson K., Kastelein R., Yssel H., and de Vries J.E. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174 (1991) 915-924
13. Dinarello C.A. The IL-1 family and inflammatory diseases. Clin. Exp. Rheumatol. 20 (2002) S1-S13
14. Fadok V.A., Bratton D.L., and Henson P.M. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J. Clin. Invest. 108 (2001) 957-962
15. Fox H. The significance of villous syncytial knots in the human placenta. J. Obstet. Gynaecol. Br. Commonw. 72 (1965) 347-355
16. Fox H. Perivillous fibrin deposition in the human placenta. Am. J. Obstet. Gynecol. 98 (1967) 245-251
17. Hawes C.S., Suskin H.A., Petropoulos A., Latham S.E., and Mueller U.W. A morphologic study of trophoblast isolated from peripheral blood of pregnant women. Am. J. Obstet. Gynecol. 170 (1994) 1297-1300
18. Huppertz B., Frank H.G., Kingdom J.C., Reister F., and Kaufmann P. Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem. Cell. Biol. 110 (1998) 495-508
19. Huppertz B., Kingdom J., Caniggia I., Desoye G., Black S., Korr H., and Kaufmann P. Hypoxia favours necrotic versus apoptotic shedding of placental syncytiotrophoblast into the maternal circulation. Placenta 24 (2003) 181-190
20. Huppertz B., Tews D.S., and Kaufmann P. Apoptosis and syncytial fusion in human placental trophoblast and skeletal muscle. Int. Rev. Cytol. 205 (2001) 215-253
21. Ichikawa N., Zhai Y.L., Shiozawa T., Toki T., Noguchi H., Nikaido T., and Fujii S. Immunohistochemical analysis of cell cycle regulatory gene products in normal trophoblast and placental site trophoblastic tumor. Int. J. Gynecol. Pathol. 17 (1998) 235-240
22. Johansen M., Redman C.W., Wilkins T., and Sargent I.L. Trophoblast deportation in human pregnancy-its relevance for pre-eclampsia. Placenta 20 (1999) 531-539
23. Knight M., Redman C.W., Linton E.A., and Sargent I.L. Shedding of syncytiotrophoblast microvilli into the maternal circulation in pre-eclamptic pregnancies. Br. J. Obstet. Gynaecol. 105 (1998) 632-640
24. Matsuda M., Salazar F., Petersson M., Masucci G., Hansson J., Pisa P., Zhang Q.J., Masucci M.G., and Kiessling R. Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expression. J. Exp. Med. 180 (1994) 2371-2376
25. Mellor A.L., and Munn D.H. Extinguishing maternal immune responses during pregnancy: implications for immunosuppression. Semin. Immunol. 13 (2001) 213-218
26. Mellor A.L., Sivakumar J., Chandler P., Smith K., Molina H., Mao D., and Munn D.H. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nat. Immunol. 2 (2001) 64-68
27. Munn D.H., Shafizadeh E., Attwood J.T., Bondarev I., Pashine A., and Mellor A.L. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J. Exp. Med. 189 (1999) 1363-1372
28. Munn D.H., Zhou M., Attwood J.T., Bondarev I., Conway S.J., Marshall B., Brown C., and Mellor A.L. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 281 (1998) 1191-1193
29. Sargent I.L., Germain S.J., Sacks G.P., Kumar S., and Redman C.W. Trophoblast deportation and the maternal inflammatory response in pre-eclampsia. J. Reprod. Immunol. 59 (2003) 153-160
30. Schmorl G. Pathologisch-Anatomische Untersuchungen uber Puerperal Eklampsie (1893), F.C.W. Vogel, Leipzig, Germany
31. Voll R.E., Herrmann M., Roth E.A., Stach C., Kalden J.R., and Girkontaite I. Immunosuppressive effects of apoptotic cells. Nature 390 (1997) 350-351