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Autoantigens act as tissue-specific chemoattractants
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Oppenheim, J.J.1
Dong, H.F.2
Plotz, P.3
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2
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Autoantigens signal through chemokine receptors: Uveitis antigens induce CXCR3- And CXCR5-expressing lymphocytes and immature dendritic cells to migrate
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Howard OM, Dong HF, Su SB, et al. Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate. Blood 2005; 105:4207-4214. Reports the interaction of IRBP and S-Ag with receptors from the CXCR subfamily and shows that a chemoattractant peptide need not be lymphoproliferative.
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Blood
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Howard, O.M.1
Dong, H.F.2
Su, S.B.3
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3
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Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells
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Howard OM, Dong HF, Yang D, et al. Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J Exp Med 2002; 196:781-791.
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Howard, O.M.1
Dong, H.F.2
Yang, D.3
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4
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22544457164
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Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity
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Carlos CA, Dong HF, Howard OM, et al. Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity. J Immunol 2005; 175:1628-1635. First report of a tumor antigen being a chemoattractant.
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J Immunol
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Carlos, C.A.1
Dong, H.F.2
Howard, O.M.3
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5
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10744228908
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Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity
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Eriksson U, Ricci R, Hunziker L, et al. Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat Med 2003; 9:1484-1490.
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Eriksson, U.1
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Hunziker, L.3
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6
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33747188614
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Antigen targeting to endosomal pathway in dendritic cell vaccination activates regulatory T cells and attenuates tumor-immunity
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Maksimow M, Miiluniemi M, Marttila-Ichihara F, et al. Antigen targeting to endosomal pathway in dendritic cell vaccination activates regulatory T cells and attenuates tumor-immunity. Blood 2006; 108:1298-1305. Reports the need to remove regulatory T cells prior to dendritic cell activation by an autoantigen.
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Blood
, vol.108
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Maksimow, M.1
Miiluniemi, M.2
Marttila-Ichihara, F.3
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7
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14844351293
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Nucleosome, the main autoantigen in systemic lupus erythematosus, induces direct dendritic cell activation via a MyD88-independent pathway: Consequences on inflammation
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Decker P, Singh-Jasuja H, Haager S, et al. Nucleosome, the main autoantigen in systemic lupus erythematosus, induces direct dendritic cell activation via a MyD88-independent pathway: consequences on inflammation. J Immunol 2005; 174:3326-3334. The concept that a complex of autoantigens, nucleotides can activate dendritic cells without involving a toll-like receptor signal is reported here.
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J Immunol
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Decker, P.1
Singh-Jasuja, H.2
Haager, S.3
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8
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Do tissue levels of autoantigenic aminoacyl-tRNA synthetase predict clinical disease?
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Kron MA, Petridis M, Haertlein M, et al. Do tissue levels of autoantigenic aminoacyl-tRNA synthetase predict clinical disease? Med Hypotheses 2005; 65:1124-1127. Reports the levels of AsnRS expression in various tissues.
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Med Hypotheses
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Kron, M.A.1
Petridis, M.2
Haertlein, M.3
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9
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Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy
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Casciola-Rosen L, Nagaraju K, Plotz P, et al. Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy. J Exp Med 2005; 201:591-601. Reports the levels of HisRS expressed at rest and during different stresses in tissues.
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J Exp Med
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Casciola-Rosen, L.1
Nagaraju, K.2
Plotz, P.3
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10
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Two distinct cytokines released from a human aminoacyl-tRNA synthetase
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Wakasugi K, Schimmel P. Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science 1999; 284:147-151.
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Wakasugi, K.1
Schimmel, P.2
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11
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Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis
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Le Y, Ye RD, Gong W, et al. Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis. FEBS J 2005; 272:769-778. Summary of current formylated methionine-leucine-phenylalanine receptor ligands and their contact domains on formyl peptide receptor-like 1.
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Le, Y.1
Ye, R.D.2
Gong, W.3
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12
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Myosin light chain kinase mediates eosinophil chemotaxis in a mitogen-activated protein kinase-dependent manner
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Adachi T, Stafford S, Kayaba H, et al. Myosin light chain kinase mediates eosinophil chemotaxis in a mitogen-activated protein kinase-dependent manner. J Allergy Clin Immunol 2003; 111:113-116.
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Adachi, T.1
Stafford, S.2
Kayaba, H.3
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The immunopathology of chemotactic cytokines: The role of interleukin-8 and monocyte chemoattractant protein-1
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Strieter, R.M.1
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Chemokines in rheumatic diseases
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Szekanecz Z, Szucs G, Szanto S, Koch AE. Chemokines in rheumatic diseases. Curr Drug Targets 2006; 7:91-102. This is a nice review of the field of chemokines and it summarizes the current status of chemokine antagonists.
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Curr Drug Targets
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Szekanecz, Z.1
Szucs, G.2
Szanto, S.3
Koch, A.E.4
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15
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Alpha-chemokine receptors CXCR1-3 and their ligands in idiopathic inflammatory myopathies
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De Paepe B, De Keyzer K, Martin JJ, De Bleecker JL. Alpha-chemokine receptors CXCR1-3 and their ligands in idiopathic inflammatory myopathies. Acta Neuropathol (Berl) 2005; 109:576-582. Reports levels of chemokines and chemokine receptors in myopathies.
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Acta Neuropathol
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De Paepe, B.1
De Keyzer, K.2
Martin, J.J.3
De Bleecker, J.L.4
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Beta-chemokine receptor expression in idiopathic inflammatory myopathies
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De Paepe B, De Bleecker JL. Beta-chemokine receptor expression in idiopathic inflammatory myopathies. Muscle Nerve 2005; 31:621-627. Continues the earlier study showing the status of the few receptors not previously reported.
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Muscle Nerve
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De Paepe, B.1
De Bleecker, J.L.2
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Expression of the beta chemokines CCL3, CCL4, CCL5 and their receptors in idiopathic inflammatory myopathies
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Civatte M, Bartoli C, Schleinitz N, et al. Expression of the beta chemokines CCL3, CCL4, CCL5 and their receptors in idiopathic inflammatory myopathies. Neuropathol Appl Neurobiol 2005; 31:70-79.
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Civatte, M.1
Bartoli, C.2
Schleinitz, N.3
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18
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Abnormal expression of chemokine receptors in Behcet's disease: Relationship to intracellular Th1/Th2 cytokines and to clinical manifestations
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Houman H, Hamzaoui A, Ben Ghorbal I, et al. Abnormal expression of chemokine receptors in Behcet's disease: relationship to intracellular Th1/Th2 cytokines and to clinical manifestations. J Autoimmun 2004; 23:267-273.
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Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action
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Disruption of CCL21-induced chemotaxis in vitro and in vivo by M3, a chemokine-binding protein encoded by murine gammaherpesvirus 68
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Jensen KK, Chen SC, Hipkin RW, et al. Disruption of CCL21-induced chemotaxis in vitro and in vivo by M3, a chemokine-binding protein encoded by murine gammaherpesvirus 68. J Virol 2003; 77:624-630.
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Stanford, M.1
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