Reduction of corneal permeability in patients treated with HP-Guar: A fluorophotometric study;Reducción de la permeabilidad corneal en pacientes tratados con HP-Guar: Estudio fluorofotométrico

Archivos de la Sociedad Espanola de Oftalmologia

Volumn 81, Issue 6, 2006, Pages 327-332

  Cerván López, Ignacio ^a   Saenz Frances San Baldomero F ^a   Benitez Del Castillo J M ^a   Garcia Sanchez J ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Artificial tears; Dry eye; Epithelial permeability; Fluorophotometry; HP Guar

Indexed keywords

EYE DROPS;

ARTICLE; COMPARATIVE STUDY; CORNEA; CORNEA EPITHELIUM; DRY EYE; FLUOROPHOTOMETRY; HUMAN; METABOLISM; PERMEABILITY; PROSPECTIVE STUDY; STATISTICAL ANALYSIS;

CORNEA; DATA INTERPRETATION, STATISTICAL; DRY EYE SYNDROMES; EPITHELIUM, CORNEAL; FLUOROPHOTOMETRY; HUMANS; OPHTHALMIC SOLUTIONS; PERMEABILITY; PROSPECTIVE STUDIES;

EID: 33750143852     PISSN: 03656691     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J 1995; 21: 221-232.
2. Mather WD. Why the eye becomes dry: a cornea and lacrimal gland feedback model. CLAO J 2000; 26: 159-165.
3. Mircheff AK. Hormonal support of lacrimal function, primary lacrimal deficiency, autoinmunity and peripheral tolerance in the lacrimal gland. Ocul Immunol Inflamm 1996; 4: 145-152.
4. Azzarolo AM, Mircheff AK, Kaswan RL, Stanczyk FZ, Gentschein E, Becker L. Androgen support of lacrimal gland function. Endocrine 1997; 6: 39-45.
5. Stern ME, Beuerman RW, Fox RI, Gao J, Mircheff AK, Pflugfelder SC. The pathology of dry eye: the interaction between the ocular surface and lacrimal glands. Cornea 1998; 17: 584-589.
6. Jones DT, Monroy D, Ji Z, Pflugfelder SC. Alterations of ocular surface gene expresión in Sjogren's syndrome. Adv Exp Med Biol 1998; 438: 533-536.
7. de Kruijf EJ, Boot JP, Laterveer L, van Best JA, Ramselaar JA, Oosterhuis JA. A simple method for determination of corneal epithelial permeability in humans. Curr Eye Res 1987; 6: 1327-1334.
8. Araie M, Maurice D. The rate of diffusion of fluorophores through the corneal epithelium and stroma. Exp Eye Res 1987; 44: 73-87.
9. Gobbels M, Spitznas M. Corneal epithelial permeability of dry eyes before and after treatment with artificial tears. Ophthalmology 1992; 99: 873-878.
10. Gobbels M, Spitznas M. Effects of artificial tears on corneal epithelial permeability in dry eyes. Graefes Arch Clin Exp Ophthalmol 1991; 229: 345-349.
11. Gobbels M, Spitznas M. Influence of artificial tears on corneal epithelim in dry-eye syndrome. Graefes Arch Clin Exp Ophthalmol 1989; 227: 139-141.
12. Ubels JL, Clousing DP, Van Haitsma TA, Hong BS, Stauffer P, Asgharian B, et al. Pre-clinical investigation of the efficacy of an artificial tear solution containing hydroxypropyl-guar as a gelling agent. Curr Eye Res 2004; 28: 437-444.
13. Hartstein I, Khwarg S, Przydryga J. An open-label evaluation of HP-Guar gellable lubricant eye drops for the improvement of dry eye signs and symtoms in a moderate dry eye adult population. Curr Med Res Opin 2005; 21: 255-260.
14. Clinch TE, Benedetto DA, Felberg NT, Laibson PR. Schirmer's test. A closer look. Arch Ophthalmol 1983; 101: 1383-1386.
15. Murube J, Benítez del Castillo JM, Chenzhuo L, Berta A, Rolando M. The Madrid triple classification of dry eye. Arch Soc Esp Oftalmol 2003; 78: 587-593.
16. Miyata K, Amano S, Sawa M, Nishida T. A novel grading method for superficial punctate keratopathy magnitude and its correlation with corneal epithelial permeability. Arch Ophthalmol 2003; 121: 1537-1539.
17. Yokoi N, Kinoshita S, Akiyama K. A new slit-lamp fluorophotometer for the clinical evaluation of corneal epithelial barrier function. Nippon Ganka Gakkai Zasshi 1994; 98: 641-647.
18. Boets EP, van Best JA. Corneal autofluorescence and epithelial barrier function. Cornea 1994; 13: 373-374.
19. Ichijima H, Yokoi N, Nishizawa A, Kinoshita S. Fluorophotometric assessment of rabbit corneal epithelial barrier function after rigid contact lens wear. Cornea 1999; 18: 87-91.
20. McNamara NA, Polse KA, Fukunaga SA, Maebori JS, Suzuki RM. Soft lens extended wear affects epithelial barrier function. Ophthalmology 1998; 105: 2330-2335.
21. Boets EP, van Best JA, Boot JP, Oosterhuis JA. Corneal epithelial permeability and daily contact lens wear as determined by fluorophotometry. Curr Eye Res 1988; 7: 511-514.
22. Niiya A, Yokoi N, Matsumoto Y, Komuro A, Ishibashi T, Tomii S, et al. Effect of beta-blocker eyedrops on corneal epithelial barrier function. Ophthalmologica 2000; 214: 332-336.
23. McCarey BE, Reaves TA. Effects of tear lubricating solutions on in vivo corneal epithelial permeability. Curr Eye Res 1997; 16: 44-50.
24. Shimazaki J, Fujishima H, Yagi Y, Tsubota K. Effects of diclofenac eye drops on corneal epithelium structure and function after small-incision cataract surgery. Ophthalmology 1996; 103: 50-57.
25. Benitez del Castillo JM, Castillo A, Toledano N, Duran S, del Aguila C, Otero M, et al. Influence of topical cyclosporine A and dissolvent on corneal epithelium permeability of fluorescein. Doc Ophthalmol 1995; 91: 49-55.
26. de Jong C, Stolwijk T, Kuppens E, de Keizer R, van Best J. Topical timolol with and without benzalkonium chloride: epithelial permeability and autofluorescence of the cornea in glaucoma. Graefes Arch Clin Exp Ophthalmol 1994; 232: 221-224.
27. Benitez del Castillo JM, del Aguila C, Duran S, Hernandez J, Garcia Sánchez J. Influence of topically applied cyclosporine A in olive oil on corneal epithelium permeability. Cornea 1994; 13: 136-140.
28. Gobbels M, Spitznas M. Corneal epithelial permeability of dry eyes before and after treatment with artificial tears. Ophthalmology 1992; 99: 873-878.
29. Ramselaar JA, Boot JP, van Haeringen NJ, van Best JA, Oosterhuis JA. Corneal epithelial permeability after instillation of ophthalmic solutions containing local anaesthetics and preservatives. Curr Eye Res 1988; 7: 947-950.
30. Dursun D, Wang M, Monroy D, Li DQ, Lokeshwar BL, Stern ME, et al. A mouse model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci 2002; 43: 632-638.
31. Yokoi N, Kinoshita S. Clinical evaluation of corneal epithelial barrier function with the slit-lamp fluorophotometer. Cornea 1995; 14: 485-489.
32. Khalil HA, van Best JA, de Keizer RJ. The permeability of the corneal epithelium of Graves' ophthalmopathy as determined by fluorophotometry. Doc Ophthalmol 1989; 73: 249-254.
33. Stolwijk TR, van Best JA, Boor JP, Lemkes HH, Oosterhuis JA. Corneal epithelial barrier function after oxybuprocaine provocation in diabetics. Invest Ophthalmol Vis Sci 1990; 31: 436-439.
34. Chang SW, Hsu HC, Chen MS. Corneal autofluorescence and epithelial barrier function in diabetic patients. Ophthalmic Res 1995; 27: 74-79.
35. Yokoi K, Yokoi N, Kinoshita S. Impairment of ocular surface epithelium barrier function in patients with atopic dermatitis. Br J Ophthalmol 1998; 82: 797-800.
36. Nakamura M, Kawahara M, Nakata K, Nishida T. Restoration of corneal epithelial barrier function and wound healing by substance P and IGF-1 in rats with capsaicin-induced neurotrophic keratopathy. Invest Ophthalmol Vis Sci 2003; 44: 2937-2940.
37. Goebbels M, Spitznas M. Effects of artificial tears on corneal epithelial permeability in dry eyes. Graefes Arch Clin Exp Ophthalmol 1991; 229: 345-349.
38. Norn MS, Opauszki A. Effects of ophthalmic vehicles on the stability of the precorneal tear film. Acta Ophthalmol (Copenh) 1977; 55: 23-34.
39. Krishna N, Brow F. Polyvinyl alcohol as an ophthalmic vehicle. Effect on regeneration of corneal epithelium. Am J Ophthalmol 1964; 57: 99-106.
40. Christensen MT, Cohen S, Rinelhart J, Akers F, Pemberton B, Bloomenstein M, et al. Clinical evaluation of an HP-guar gellable lubricant eye drop for the relief of dryness of the eye. Curr Eye Res 2004; 28: 55-62.
41. Lopez Bernal D, Ubels JL. Artificial tear composition and promotion of recovery of the damaged corneal epithelium. Cornea 1993; 12: 115-120.
42. Lopez Bernal D, Ubels JL. Quantitative evaluation of the corneal epithelial barrier: effect of artificial tears and preservatives. Curr Eye Res 1991; 10: 645-656.
43. Tripathi BJ, Tripati RC, Kolli SP. Cytotoxicity of ophthalmic preservatives on human corneal epithelium. Lens Eye Toxic Res 1992; 9: 361-367.