Effect of rosmarinic acid against PC12 cell injures induced by glutamate

Chinese Pharmacological Bulletin

Volumn 22, Issue 8, 2006, Pages 955-959

  Yan, Tao ^a   Yan, Feng Xiang ^a   Zhou, Jia Mao ^b   Zhu, Bing Yang ^a   Gong, Yong Zhen ^a   Xu, Can Xin ^a   Chi, Xiu Ling ^a   Zhang, Hai Qiang ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b Dept of Medine   (China)

Author keywords

Apoptosis; bax; bcl; Glutamate; PC12 cells; Rosmarinic acid

Indexed keywords

GLUTAMIC ACID; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PROTEIN BAX; PROTEIN BCL XL; ROSMARINIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL LEVEL; CELL STRAIN; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; INCUBATION TIME; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 33750092443     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Shimohama S, Ogawa N, Tamura Y, et al. Protective effect of nerve growth factor against glutamate-induced neurotoxicity in cultured cortical neurons[J]. Brain Res, 1993, 632(1-2):296-302.
2. Ono K, Hasegawa K, Naiki H, et al. Curcumin has potent antiamyloidogenic effects for Alzheimers beta-amyloid fibrils in vitro [J]. J Neurosci Res, 2004, 75(6):742-50.
3. Shafer T J, Atchison W D. Transmitter, ion channel and receptor properties of pheochromo-cytoma (PC12) cells:a model for neurotoxicological studies[J]. Neurotoxicology, 1991, 12(3):473-92.
4. +. Chin pharmacol Ball, 2005, 21 (3):335-9.
5. Li W, Pi K, Chan H H, et al. Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors[J]. J Biol Chem, 2005, 280(18):18179-88.
6. Zitterkopf N L, McNeal D W, Eyster K M, et al. Lactate dehydrogenase-elevating virus induces apoptosis in cultured macrophages and in spinal cords of C58 mice coincident with onset of murine amyotrophic lateral sclerosis[J]. Virus Res, 2004 Nov, 106(1):35 -42.
7. Tatton W G, Chalmers-Redman R, Brown D, et al. Apoptosis in Parkinsons disease: signals for neuronal degradation[J]. Ann Neurol, 2003, 53(Suppl 3):S61-70.
8. Choi D W. Excitotoxic cell death[J]. J Neurobiol, 1992, 23(9): 1261-76.
9. Montoliu C, Monfort P, Carrasco J, et al. Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons[J]. J Neurochem, 2000, 75(1):266-73.
10. Meldrum B S. Glutamate as a neurotransmitter in the brain: review of physiology and pathology[J]. J Nutr, 2000, 130(4S Suppl): S1007-15.
11. Smith T, Groom A, Zhu B, et al. Autoimmune encephalomyelitis ameliorated by AMPA antagonists[J]. Nat Med, 2000, 6(1):62-6.
12. Zhu D, Wu X, Strauss K I, et al. N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway[J]. J Neurosci Res, 2005, 80(1):104-13.
13. Schelman W R, Andres R D, Sipe K J, et al. Glutamate mediates cell death and increases the Bax to Bcl-2 ratio in a differentiated neuronal cell line[J]. Brain Res Mol Brain Res, 2004, 128(2): 160-9.
14. Howard S, Bottino C, Brooke S, et al. Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: interactions with pathways of oxidative damage[J]. J Neurochem, 2002, 83(4):914 -23.
15. Gao L P, Wei H L, Zhao I I S, et al. Antiapoptotic and antioxidant effects of rosmarinic acid in astrocytes [J]. Pharmazie, 2005, 60 (1):62-5.