Factors influencing hemorrhagic transformation in ischemic stroke: A clinicopathological comparison

European Journal of Neurology

Volumn 13, Issue 11, 2006, Pages 1251-1255

  Kerenyi, L ^a,d   Kardos, L ^b   Szasz J ^c   Szatmari S ^c   Bereczki, D ^a   Hegedus K ^a   Csiba, L ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b Contract Medical Statistician ^*  (Hungary)

^c UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^d Department of Internal Medicine   (Hungary)

Author keywords

Acute ischemic stroke; Diabetes mellitus; Hemorrhagic transformation; Pathology

Indexed keywords

GLUCOSE;

ADULT; AGE; AGED; ARTICLE; AUTOPSY; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NEUROPATHOLOGY; PRIORITY JOURNAL; RISK FACTOR;

EID: 33750076048     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2006.01489.x     Document Type: Article

References (28)

1. Okada Y, Yamaguchi T, Minematsu K et al. Hemorrhagic transformation in cerebral embolism. Stroke 1989; 20: 598-603.
2. Fiorelli M, Bastianello S, von Kummer R et al. Hemorrhagic transformation within 36 hours of a cerebral infarct: relationships with early clinical deterioration and 3-month outcome in the European Cooperative Acute Stroke Study I (ECASS I) cohort. Stroke 1999; 30: 2280-2284.
3. Larrue V, von Kummer RR, Muller A, Bluhmki E. Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke 2001; 32: 438-441.
4. Castellanos M, Leira R, Serena J et al. Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke. Stroke 2003; 34: 40-46.
5. Larrue V, von Kummer R, del Zoppo G et al. Hemorrhagic transformation in acute ischemic stroke. Potential contributing factors in the European Cooperative Acute Stroke Study. Stroke 1997; 28: 957-960.
6. Clark WM, Wissman S, Albers GW, Jhamandas JH, Madden KP, Hamilton S. Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. Journal of the American Medical Association 1999; 282: 2019-2026.
7. Hacke W, Donnan G, Fieschi C et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004; 363: 768-774.
8. The NINDS t-PA Stroke Study Group. Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. Stroke 1997; 28: 2109-2118.
9. Lindsberg PJ, Soinne L, Roine RO et al. Community-based thrombolytic therapy of acute ischemic stroke in Helsinki. Stroke 2003; 34: 1443-1449.
10. Bruno A, Levine SR, Frankel MR et al. for the NINDS rt-PA Stroke Study Group. Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology 2002; 59: 669-674.
11. Kittner SJ, Sharkness CM, Sloan MA et al. Infarcts with a cardiac source of embolism in the NINDS Stroke Data Bank: neurologic examination. Neurology 1992; 42: 299-302.
12. Levy D. Clinical significance of left ventricular hypertrophy: insights from the Framingham Study. Journal of Cardiovascular Pharmacology 1991; 17(Suppl. 2):S1-S6.
13. Hornig CR, Bauer T, Simon C, Trittmacher S, Dorndorf W. Hemorrhagic transformation in cardioembolic cerebral infarction. Stroke 1993; 24: 465-468.
14. Molina CA, Montaner J, Abilleira S et al. Timing of spontaneous recanalization and risk of hemorrhagic transformation in acute cardioembolic stroke. Stroke 2001; 32: 1079-1084.
15. Del Zoppo GJ, Von Kummer R, Hamann GF. Ischaemic damage of brain microvessels: inherent risks for thrombolytic treatment in stroke. Journal of Neurology Neurosurgery and Psychiatry 1998; 65: 1-9.
16. Weir CJ, Murray GD, Dyker AG, Lees KR. Is hyperglycemia an independent predictor of poor outcome after acute stroke? Results of a long-term follow up study. British Medical Journal 1997; 314: 1303-1306.
17. Demchuk AM, Morgenstern LB, Krieger DW et al. Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke. Stroke 1999; 30: 34-39.
18. Jaillard A, Cornu C, Durieux A et al. Hemorrhagic transformation in acute ischemic stroke. The MAST-E study. MAST-E Group. Stroke 1999; 30: 1326-1332.
19. Fukumoto H, Naito Z, Asano G et al. Immunohistochemical and morphometric evaluations of coronary atherosclerotic plaques associated with myocardial infarction and diabetes mellitus. Journal of Atherosclerosis and Thrombosis 1998; 5: 29-35.
20. Hussain MJ, Peakman M, Gallati H et al. Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM. Diabetologia 1996; 39: 60-69.
21. Uemura S, Matsushita H, Li W et al. Diabetes mellitus enhances vascular matrix metalloproteinase activity: role of oxidative stress. Circulation Research 2001; 88: 1291-1298.
22. Romanic AM, Madri JA. Extracellular matrix-degrading proteinases in the nervous system. Brain Pathology 1994; 4: 145-156.
23. Hafer-Macko CE, Ivey FM, Gyure KA et al. Thrombomodulin deficiency in human diabetic nerve microvasculature. Diabetes 2002; 51: 1957-1963.
24. Ceriello A, Giugliano D, Quatraro A et al. Evidence for a hyperglycaemia-dependent decrease of antithrombin III-thrombin complex formation in humans. Diabetologia 1990; 33: 163-167.
25. Ceriello A, Giacomello R, Stel G et al. Hyperglycemia-induced thrombin formation in diabetes: the possible role of oxidative stress. Diabetes 1995; 44: 924-928.
26. Pandolfi A, Cetrullo D, Polishuck R et al. Plasminogen activator inhibitor type 1 is increased in the arterial wall of type II diabetic subjects. Arteriosclerosis Thrombosis Vascular Biology 2001; 21: 1378-1382.
27. Palomaki H, Kaste M. Regular light-to-moderate intake of alcohol and the risk of ischemic stroke. Is there a beneficial effect? Stroke 1993; 24: 1828-1832.
28. Reynolds K, Lewis B, Nolen JD, Kinney GL, Sathya B, He J. Alcohol consumption and risk of stroke: a meta-analysis. Journal of the American Medical Association 2003; 289: 579-588.