-
1
-
-
22244479672
-
Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic therapy
-
OShea C, Soria C, Bagus B, McCormick F: Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic therapy. Cancer Cell 8, 61-74 (2005).
-
(2005)
Cancer Cell
, vol.8
, pp. 61-74
-
-
Oshea, C.1
Soria, C.2
Bagus, B.3
McCormick, F.4
-
2
-
-
4344564103
-
Oncolytic viruses for the treatment of cancer: Current strategies and clinical trials
-
Ries S, Brandts C: Oncolytic viruses for the treatment of cancer: current strategies and clinical trials. Drug Discov. Today 9(17), 759-768 (2004).
-
(2004)
Drug Discov. Today
, vol.9
, Issue.17
, pp. 759-768
-
-
Ries, S.1
Brandts, C.2
-
3
-
-
0037033736
-
ONYX-015: Mechanisms of action and clinical potential of a replication-selective adenovirus
-
Ries S, Korn M: ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus. Br. J. Cancer 86, 5-11 (2002).
-
(2002)
Br. J. Cancer
, vol.86
, pp. 5-11
-
-
Ries, S.1
Korn, M.2
-
4
-
-
0023099280
-
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
-
Barker DD, Berk AJ: Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology 156, 107-121 (1987).
-
(1987)
Virology
, vol.156
, pp. 107-121
-
-
Barker, D.D.1
Berk, A.J.2
-
5
-
-
0030001373
-
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor
-
Dobner T, Horikoshi N, Rubenwolf S, Shenk T: Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor. Science 272(5267), 1470-1473 (1996).
-
(1996)
Science
, vol.272
, Issue.5267
, pp. 1470-1473
-
-
Dobner, T.1
Horikoshi, N.2
Rubenwolf, S.3
Shenk, T.4
-
6
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A et al.: An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274, 373-376 (1996).
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
7
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I et al.: A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nature Med. 6, 879-885 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
8
-
-
0031798440
-
P53 status does not determine outcome of E1B 55- kilodalton mutant adenovirus lytic infection
-
Goodrum FD, Ornelles DA: p53 status does not determine outcome of E1B 55- kilodalton mutant adenovirus lytic infection. J. Virol. 72, 9479-9490 (1999).
-
(1999)
J. Virol.
, vol.72
, pp. 9479-9490
-
-
Goodrum, F.D.1
Ornelles, D.A.2
-
9
-
-
0033022039
-
P53-independent and -dependent requirements for E1B-55K in adenovirus Type 5 replication
-
Harada JN, Berk AJ: p53-independent and -dependent requirements for E1B-55K in adenovirus Type 5 replication. J. Virol. 73, 7474-7488 (1999).
-
(1999)
J. Virol.
, vol.73
, pp. 7474-7488
-
-
Harada, J.N.1
Berk, A.J.2
-
10
-
-
0022263759
-
Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport
-
Babiss LE, Ginsberg HS, Darnell JE: Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol. Cell. Biol. 5, 2552-2558 (1985).
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 2552-2558
-
-
Babiss, L.E.1
Ginsberg, H.S.2
Darnell, J.E.3
-
11
-
-
0024456615
-
The adenovirus 55kd protein influences mRNA transport via an intranuclear effect on RNA metabolism
-
Leppard KN, Shenk T: The adenovirus 55kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J. 8, 2329-2336 (1989).
-
(1989)
EMBO J.
, vol.8
, pp. 2329-2336
-
-
Leppard, K.N.1
Shenk, T.2
-
12
-
-
0022622023
-
The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs
-
Pilder S, Moore M, Logan J, Shenk T: The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol. Cell. Biol. 6, 470-476 (1986).
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 470-476
-
-
Pilder, S.1
Moore, M.2
Logan, J.3
Shenk, T.4
-
13
-
-
19944363519
-
Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
-
OShea CC, Johnson L, Bagus B et al.: Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell 6, 611-623 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 611-623
-
-
Oshea, C.C.1
Johnson, L.2
Bagus, B.3
-
14
-
-
10644298024
-
Effects of febrile temperature on adenoviral infection and replication: Implications for viral therapy of cancer
-
Thorne SH, Brooks G, Lee YL et al.: Effects of febrile temperature on adenoviral infection and replication: implications for viral therapy of cancer. J. Virol. 79, 581-591 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 581-591
-
-
Thorne, S.H.1
Brooks, G.2
Lee, Y.L.3
-
15
-
-
0038004636
-
Clinical biomarkers in drug discovery and development
-
Frank R, Hargreaves R: Clinical biomarkers in drug discovery and development. Nature 2(7), 566-580 (2003).
-
(2003)
Nature
, vol.2
, Issue.7
, pp. 566-580
-
-
Frank, R.1
Hargreaves, R.2
|