In situ studies of regional absorption of lobucavir and ganciclovir from rabbit intestine and predictions of dose-limited absorption and associated variability in humans

Journal of Pharmaceutical Sciences

Volumn 95, Issue 10, 2006, Pages 2276-2292

  Yang, Zheng ^a,b   Manitpisitkul, Prasarn ^b,c   Sawchuk, Ronald J ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Dose limited absorption; Ganciclovir; in situ perfusion; Intersubject variability; Lobucavir

Indexed keywords

GANCICLOVIR; LOBUCAVIR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STRUCTURE; IN VITRO STUDY; INTESTINE ABSORPTION; INTESTINE TRANSIT TIME; NONHUMAN; RABBIT; SIMULATION;

EID: 33750014238     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20716     Document Type: Article

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