Hepatocyte nuclear factor-4α contributes to carbohydrate-induced transcriptional activation of hepatic fatty acid synthase

Biochemical Journal

Volumn 399, Issue 2, 2006, Pages 285-295

  Adamson, Aaron W ^a   Suchankova, Gabriela ^b   Rufo, Caterina ^c   Nakamura, Manabu T ^d   Teran Garcia, Margarita ^a   Clarke, Steven D ^e   Gettys, Thomas W ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b BOSTON MEDICAL CENTER   (United States)

^c UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e McNeil Nutritionals   (United States)

Author keywords

Carbohydrate response element binding protein (ChREBP); Direct repeat 1 (DR 1); Fatty acid synthase (FAS); Hepatocyte nuclear factor 4 (HNF 4 ); Primary hepatocyte; Transcriptional activation

Indexed keywords

CARBOHYDRATE RESPONSE ELEMENT-BINDING PROTEIN (CHREBP); DIRECT REPEAT-1 (DR-1); FATTY ACID SYNTHASE (FAS); HEPATOCYTE NUCLEAR FACTOR 4Α (HNF-4Α); PRIMARY HEPATOCYTE; TRANSCRIPTIONAL ACTIVATION;

ACTIVATION ANALYSIS; BIOLOGICAL ORGANS; CARBOHYDRATES; FATTY ACIDS; GENES; GLUCOSE; OXIDATION;

ENZYMES;

BINDING PROTEIN; CARBOHYDRATE; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; FATTY ACID SYNTHASE; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASE PAIRING; CARBOHYDRATE INTAKE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FOOTPRINTING; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; REFEEDING; TRANSCRIPTION INITIATION;

ANIMALS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; ENHANCER ELEMENTS (GENETICS); FATTY ACID SYNTHETASE COMPLEX; FOOD DEPRIVATION; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMANS; LIVER; LIVER EXTRACTS; MALE; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; REPETITIVE SEQUENCES, NUCLEIC ACID; TRANS-ACTIVATION (GENETICS);

EID: 33749991421     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060659     Document Type: Article

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