A stereoselective anti-aldol route to (3R,3aS,6aR)-hexahydrofuro[2,3-b] furan-3-ol: A key ligand for a new generation of HIV protease inhibitors

Synthesis

Volumn , Issue 18, 2006, Pages 3015-3018

  Ghosh, Arun K ^a   Li, Jianfeng ^a   Perali, Ramu Sridhar ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Aldol reactions; Antiviral agents; Asymmetric synthesis; Chiral auxiliary; Fused ring systems

Indexed keywords

ALDOL REACTIONS; ANTIVIRAL AGENTS; ASYMMETRIC SYNTHESIS; CHIRAL AUXILIARY; FUSED RING SYSTEMS;

ESTERS; FURAN RESINS; REACTION KINETICS; SYNTHESIS (CHEMICAL); TITANIUM COMPOUNDS;

ENZYME INHIBITION;

BRECANAVIR; DARUNAVIR; HEXAHYDROFURO(2,3)FURAN 3 OL; PROTEINASE INHIBITOR; TETRAHYDROFURAN DERIVATIVE; TITANIUM; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY;

EID: 33749514977     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942547     Document Type: Article

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