The multifunctional carotenoids: Insights into their behavior

Journal of Nutrition

Volumn 136, Issue 10, 2006, Pages

  Russell, Robert M ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; BIOLOGICAL MARKER; CAROTENOID; CYTOCHROME P450; REACTIVE OXYGEN METABOLITE;

CANCER INCIDENCE; CANCER RISK; CANCER SURVIVAL; CARCINOGENESIS; CIGARETTE SMOKING; CLINICAL TRIAL; COMET ASSAY; CONFERENCE PAPER; DIET SUPPLEMENTATION; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; HUMAN; IN VIVO STUDY; LUNG CANCER; OXIDATIVE STRESS; SQUAMOUS CELL METAPLASIA;

EID: 33749476627     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.10.2690s     Document Type: Conference Paper

References (18)

1. Duthie S, Ma A, Ross M, Collins A. Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer Res. 1996;56:1291-5.
2. Cutler RG, Rodriguez H., eds. Critical reviews of oxidative stress and aging. Carotenoids and oxidative stress, Hackensack, NJ: World Scientific Publishing Company, 2002;1:598-610.
3. Ziegler R, Mayne S, Swanson C. Nutrition and lung cancer. Cancer Causes Control. 1996;7:157-77.
4. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029-35.
5. Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, et al. Effects of a combination of β-carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334:1150-5.
6. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, Belanger C, LaMotte F, Gaziano JM, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996;334:1145-9.
7. Bairati I, Meyer F, Gélinas M, Fortin A, Nabid A, Brochet F, Mercier J-P, Têtu B, Harel F, et al. A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst. 2005;97:481-8.
8. Fiala ES, Sohn OS, Wang C-X, Seibert E, Tsurutani J, Dennis PA, El-Bayoumy K, Sodum RS, Desai D, et al. Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E. Carcinogenesis. 2005;26:605-12.
9. Young A, Lowe G. Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys. 2001;385:20-7.
10. Palozza P. Prooxidant actions of carotenoids in biologic systems. Nutr Rev. 1998;56:257-65.
11. Wang X-D, Liu C, Bronson RT, Smith DE, Krinsky KI, Russell RM. Retinoid signaling and activator protein-1 expression in ferrets given β-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst. 1999;91:60-6.
12. Salgo MG, Cueto R, Winston GQ, Pryor WA. β-Carotene and its oxidation products have different effects on microsome mediated binding of benzo[a]pyrene to DNA. Free Radic Biol Med. 1999;26:162-73.
13. Perocco P, Paolini M, Mazzullo M, Biagi GL, Cantelli-Forti G. β-Carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro. Mutat Res. 1999;440:83-90.
14. Wang X-D, Liu C, Bronson RT, Smith DE, Krinsky KI, Russell RM. Effects of physiological versus pharmacological β-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis. 2000;21:2245-53.
15. Yeum K-J, Russell RM, Krinsky NI, Aldini G. Biomarkers of antioxidant capacity in the hydrophilic and lipophilic compartments of human plasma. Arch Biochem Biophys. 2004;430:97-103.
16. Aldini G, Yeum K-J, Russell RM, Krinsky NI. A selective assay to measure antioxidant capacity in both the aqueous and lipid compartments of plasma. Nutr Sci. 2003;6:12-9.
17. Palli D, Masala G, Vineis P, Garte S, Saieva C, Krogh V, Panico S, Tumino R, Munnia A, et al. Biomarkers of dietary intake of micronutrients modulate DNA adduct levels in healthy adults. Carcinogenesis. 2003;24:739-46.
18. Hayashi S, Yasui H, Sakurai H. Essential role of singlet oxygen species in cytochrome P450-dependent substrate oxygenation by rat liver microsomes. Drug Metab Pharmacokinet. 2005;20:14-23.