Myocardial oxygenation and high-energy phosphate levels during graded coronary hypoperfusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 1 49-1, 2001, Pages

  Zhang, Jianyi ^a,b   Ugurbil, Kamil ^a   From, Arthur H L ^a   Bache, Robert J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b University of Minnesota   (United States)

Author keywords

Blood flow; Ischemia; Myocardium; Myoglobin oxygen saturation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; MYOGLOBIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORRELATION FUNCTION; DOG; HEART INFARCTION; HEART MUSCLE BLOOD FLOW; HEART MUSCLE OXYGEN CONSUMPTION; HIGH ENERGY PHOSPHATE; IN VIVO STUDY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0034997752     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.1.h318     Document Type: Article

References (35)

1. Myocardial oxygenation in vivo: Optical spectroscopy of cytoplasmic myoglobin and mitochondrial cytochromes
2. The importance of the perfusion pressure in the coronary arteries for the contractility and oxygen consumption of the heart
3. Control of mitochondrial respiration in the heart in vivo
4. Metabolic heterogeneities in rapidly metabolizing tissues
5. 1H NMR spectroscopy
6. 2 between cytosol and mitochondrion?
7. Metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis
8. Regulation of the oxidative phosphorylation rate in the intact cell
9. Visible-light photon migration through myocardium in vivo
10. Effect of coronary perfusion pressure or coronary flow on oxygen usage of the myocardium
11. Construction and evaluation of a coronary catheter for chronic implantation in dogs
12. Spectroscopic imaging using variable angle excitation from adiabatic plane rotation pulses
13. 2 flux density at coronary capillaries
14. Oxygen dependence of energy state and cardiac work in the perfused rat heart
15. Effect of graded reductions of coronary pressure and flow on myocardial metabolism and performance: A model of "hibernating" myocardium
16. Oxygen dependence of mitochondrial function in isolated rat cardiac myocytes
17. Cellular mechanism of the modulation of contractile function by coronary perfusion pressure in forrret hearts
18. 1H nuclear magnetic resonance signal of myoglobin
19. 1H-nuclear magnetic resonance deoxymyoglobin signal as indicator of intracellular oxygenation in myocardium
20. Correlation of contractile dysfunction with oxidative energy production and tissue high-energy phosphate stores during partial coronary flow disruption in rabbit heart
21. 2 supply
22. Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia
23. Effect of flow reduction on coronary blood flow heterogeneity
24. 31P NMR spectroscopy
25. Spectroscopic imaging and spatial localization using adiabatic pulses and applications to detect transmural metabolite distribution in the canine heart
26. Spectroscopic imaging and spatial localization using adiabatic pulses and applications to detect transmural metabolite distribution in the canine heart
27. Myoglobin oxygen dissociation by multiwavelength spectroscopy
28. Regulation of oxygen diffusion in hypoxic isolated cardiac myocytes
29. 2 supply to mitochondria in actively respiring singh cardiomyocyte of rats
30. 2 gradients in a single cardiomyocyte of the rat
31. Correlation between acute reductions in myocardial blood flow and function in conscious dogs
32. Exercise induced augmentation of myocardial oxygen extraction in spite of normal coronary dilatory capacity in dogs
33. Perfusion pressure and transmural flow distribution in the left ventricles of isolated rat hearts
34. Oxygen delivery does not limit cardiac performance during high workstates
35. Monitoring of redox-state of respiratory enzymes and myoglobin oxygenation in the working rat heart in normoxia and oxygen deficiency