Localization of Haemophilus ducreyi in naturally acquired chancroidal ulcers

Microbes and Infection

Volumn 8, Issue 9-10, 2006, Pages 2465-2468

  Bauer, Margaret E ^a   Townsend, Carisa A ^a   Ronald, Allan R ^b   Spinola, Stanley M ^a,c  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bacterial localization; Chancroid; Genital ulcer; Haemophilus ducreyi

Indexed keywords

COLLAGEN; FIBRIN; FIBRONECTIN; LAMININ;

ARTICLE; BACTERIUM CULTURE; CELL INFILTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; FIBROBLAST; GENITAL ULCER; GRANULOCYTE; HISTOLOGY; HUMAN; HUMAN TISSUE; INOCULATION; KERATINOCYTE; MACROPHAGE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PUSTULE; SKIN BIOPSY; STAINING; ULCUS MOLLE;

CHANCROID; FIBRIN; HAEMOPHILUS DUCREYI; HUMANS; NEUTROPHILS; ULCER;

BACTERIA (MICROORGANISMS); EUKARYOTA; HAEMOPHILUS DUCREYI;

EID: 33749318010     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.06.001     Document Type: Article

References (19)

1. Spinola S.M., Bauer M.E., and Munson Jr. R.S. Immunopathogenesis of Haemophilus ducreyi infection (chancroid). Infect. Immun. 70 (2002) 1667-1676
2. King R., Choudhri S.H., Nasio J., Gough J., Nagelkerke N.J.D., Plummer F.A., Ndinya-Achola J.O., and Ronald A.R. Clinical and in situ cellular responses to Haemophilus ducreyi in the presence or absence of HIV infection. Intl. J. STD AIDS 9 (1998) 531-536
3. King R., Gough A., Nasio J., Ndinya-Achola F., Plummer F., and Wilkins J. An immunohistochemical analysis of naturally occurring chancroid. J. Infect. Dis. 174 (1996) 427-430
4. Magro C.M., Crowson A.N., Alfa M., Nath A., Ronald A., Ndinya-Achola J.O., and Nasio J. A morphological study of penile chancroid lesions in human immunodeficiency virus (HIV)-positive and -negative African men with a hypothesis concerning the role of chancroid in HIV transmission. Hum. Pathol. 27 (1996) 1066-1070
5. Choudhary B.P., Kumari S., Bhatia R., and Agarwal D.S. Bacteriological study of chancroid. Indian J. Med. Res. 76 (1982) 379-385
6. Zamzachin G., Gupta U., and Singh O.P. A clinico-bacteriological study of "chancroidal" ulcers, treated at AIIMS hospital, New Delhi. Indian J. Pathol. Microbiol. 29 (1986) 277-283
7. Freinkel A.L. Histological aspects of sexually transmitted genital lesions. Histopathology 11 (1987) 819-831
8. Heyman A., Beeson P.B., and Sheldon W.H. Diagnosis of chancroid. JAMA 129 (1945) 935-938
9. Marsch W.C., Haas N., and Stuttgen G. Ultrastructural detection of Haemophilus ducreyi in biopsies of chancroid. Arch. Dermatol. Res. 263 (1978) 153-157
10. Ortiz-Zepeda C., Hernandez-Perez E., and Marroquin-Burgos R. Gross and microscopic features in chancroid: a study in 200 new culture-proven cases in San Salvador, Sexually Trans. Dis. 21 (1994) 112-117
11. Sheldon W.H., and Heyman A. Studies on chancroid I. Observations on the histology with an evaluation of biopsy as a diagnostic procedure. Am. J. Pathol. 22 (1946) 415-425
12. Bauer M.E., and Spinola S.M. Localization of Haemophilus ducreyi at the pustular stage of disease in the human model of infection. Infect. Immun. 68 (2000) 2309-2314
13. Bauer M.E., Goheen M.P., Townsend C.A., and Spinola S.M. Haemophilus ducreyi associates with phagocytes, collagen, and fibrin and remains extracellular throughout infection of human volunteers. Infect. Immun. 69 (2001) 2549-2557
14. Brown T.J., Jardine J., and Ison C.A. Antibodies directed against Haemophilus ducreyi heat shock proteins. Microb. Pathog. 15 (1993) 131-139
15. Hiltke T.J., Campagnari A.A., and Spinola S.M. Characterization of a novel lipoprotein expressed by Haemophilus ducreyi. Infect. Immun. 64 (1996) 5047-5052
16. White C.D., Leduc I., Olsen B., Jeter C., Harris C., and Elkins C. Haemophilus ducreyi outer membrane determinants, including DsrA, define two clonal populations. Infect. Immun. 73 (2005) 2387-2399
17. Brentjens R.J., Ketterer M., Apicella M.A., and Spinola S.M. Fine tangled pili expressed by Haemophilus ducreyi are a novel class of pili. J. Bacteriol. 178 (1996) 808-816
18. Vakevainen M., Greenberg S., and Hansen E.J. Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins. Infect. Immun. 71 (2003) 5994-6003
19. Fulcher R.A., Cole L.E., Janowicz D.M., Toffer K.L., Fortney K.R., Katz B.P., Orndorff P.E., Spinola S.M., and Kawula T.H. Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid. Infect. Immun. 74 (2006) 2651-2658