Haemophilus ducreyi associates with phagocytes, collagen, and fibrin and remains extracellular throughout infection of human volunteers

Infection and Immunity

Volumn 69, Issue 4, 2001, Pages 2549-2557

  Bauer, M E ^a   Goheen, M P ^a   Townsend, C A ^a   Spinola, S M ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FIBRIN;

ADULT; ARTICLE; CONTROLLED STUDY; DERMIS; EPIDERMIS; FEMALE; FIBROBLAST; GRAM NEGATIVE INFECTION; HAEMOPHILUS DUCREYI; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LANGERHANS CELL; MACROPHAGE; MALE; NEUTROPHIL; NORMAL HUMAN; PHAGOCYTE; PRIORITY JOURNAL; PUSTULE; T LYMPHOCYTE;

ADULT; BACTERIAL ADHESION; COLLAGEN; FEMALE; FIBRIN; HAEMOPHILUS DUCREYI; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; NEUTROPHILS; PHAGOCYTES; SKIN; T-LYMPHOCYTES;

EID: 0035077509     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.4.2549-2557.2001     Document Type: Article

References (33)

1. Haemophilus ducreyi adheres to but does not invade cultured human foreskin cells
2. A pilus-deficient mutant of Haemophilus ducreyi is virulent in the human model of experimental infection
3. An isogenic hemoglobin receptor-deficient mutant of Haemophilus ducreyi is attenuated in the human model of experimental infection
4. Standardization of the experimental model of Haemophilus ducreyi infection in human subjects
5. Binding of Haemophilus ducreyi to extracellular matrix proteins
6. Localization of Haemophilus ducreyi at the pustular stage of disease in the human model of infection
7. DsrA-deficient mutant of Haemophilus ducreyi is impaired in its ability to infect human volunteers
8. Haemophilus ducreyi adheres to human keratinocytes
9. Expression of peptidoglycan-associated lipoprotein is required for virulence in the human model of Haemophilus ducreyi infection
10. GroEL heat shock protein of Haemophilus ducreyi: Association with cell surface and capacity to bind to eukaryotic cells
11. Characterization of a transposon Tn916-generated mutant of Haemophilus ducreyi 35000 defective in lipooligosaccharide biosynthesis
12. Immunoelectron microscopy of Pneumocystis carinii exposed to a beta-1-3 glucan synthase inhibitor LY302146
13. Effect of normal and immune sera on Haemophilus ducreyi 35000HP and its isogenic MOMP and LOS mutants
14. Characterization of a novel lipoprotein expressed by Haemophilus ducreyi
15. Haemophilus ducreyi infection causes basal keratinocyte cytotoxicity and elicits a unique cytokine induction pattern in an in vitro human skin model
16. The wound healing process
17. Serum bactericidal activity and phagocytosis in host defence against Haemophilus ducreyi
18. Evidence of Haemophilus ducreyi adherence to and cytotoxin destruction of human epithelial cells
19. In vitro model of Haemophilus ducreyi adherence to and entry into eukaryotic cells of genital origin
20. The immune response to Haemophilus ducreyi resembles a delayed-type hypersensitivity reaction throughout experimental infection of human subjects
21. Periplasmic copper-zinc superoxide dismutase protects Haemophilus ducreyi exogenous superoxide
22. Neutropenia restores virulence to an attenuated Cu, Zn superoxide dismutase-deficient Haemophilus ducreyi strain in the swine model of chancroid
23. Association of Haemophilus ducreyi with cell-culture lines
24. Cutaneous wound healing
25. Haemophilus ducreyi elicits a cutaneous infiltrate of CD4 cells during experimental human infection
26. Experimental human infection-with Haemophilus ducreyi
27. Cloning and sequencing of the gene encoding the Cu, Zn-superoxide dismutase of Haemophilus ducreyi
28. Evaluation of an isogenic MOMP-deficient mutant in the human model of Haemophilus ducreyi infection
29. Transcription of candidate virulence genes of Haemophilus ducreyi during infection of human volunteers
30. Haemophilus ducreyi attaches to and invades human epithelial cells in vitro
31. Target cell range of Haemophilus ducreyi hemolysin and its involvement in invasion of human epithelial cells
32. Expression of cytolethal distending toxin and hemolysin are not required for pustule formation by Haemophilus ducreyi in human volunteers
33. Examination of early interactions between Haemophilus ducreyi and host cells by using cocultured HaCaT keratinocytes and foreskin fibroblasts