An aqueous polysaccharide extract from the edible mushroom Pleurotus ostreatus induces anti-proliferative and pro-apoptotic effects on HT-29 colon cancer cells

Cancer Letters

Volumn 244, Issue 1, 2006, Pages 61-70

  Lavi, Iris ^a   Friesem, Dana ^a   Geresh, Shimona ^b   Hadar, Yitzhak ^a   Schwartz, Betty ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Apoptosis; Colon cancer cells; Glucans; Pleurotus ostreatus

Indexed keywords

GLUCAN; POLYSACCHARIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CELL PROLIFERATION; COLON CARCINOMA; CONTROLLED STUDY; CYTOSOL; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; MUSHROOM; PLEUROTUS OSTREATUS; PRIORITY JOURNAL; SOLUBILITY; UPREGULATION;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL PROLIFERATION; CYTOCHROMES C; CYTOSOL; GLUCANS; HT29 CELLS; HUMANS; MOLECULAR WEIGHT; PLANT EXTRACTS; PLEUROTUS;

BASIDIOMYCOTA; PLEUROTUS OSTREATUS;

EID: 33749267630     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2005.12.007     Document Type: Article

References (26)

1. Wasser S.P., and Weis A.L. Therapeutic effects of substances occurring in higher basidiomycetes mushrooms: a modern perspective. Crit. Rev. Immunol. 19 (1999) 65-96
2. Mizuno T., Saito H., Nishitoba T., and Kawagishi H. Antitumor-active substances from mushrooms. Food Rev. Int. 11 (1995) 23-61
3. Jong S.C., and Birmingham J.M. Medicinal and therapeutic value of the shiitake mushroom. Adv. Appl. Microbiol. 39 (1993) 153-184
4. Chang R. Functional properties of edible mushrooms. Nutr. Rev. 54 (1996) S91-S93
5. Mitamura T., Sakamoto S., Suzuki S., Yoshimura S., Maemura M., and Kudo H. Effects of lentinan on colorectal carcinogenesis in mice with ulcerative colitis. Oncol. Rep. 7 3 (2000) 599-601
6. Ng M.L., and Yap A.T. Inhibition of human colon carcinoma development by lentinan from shiitake mushrooms (Lentinus edodes). J. Altern. Complement. Med. 8 5 (2002) 581-589
7. Cheung N.K., Modak S., Vickers A., and Knuckles B. Orally administered β-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol. Immunother. 51 10 (2002) 557-564
8. Ardon O., Kerem Z., and Hadar Y. Enhancement of lignin degradation and laccase activity in Pleurotus ostreatus by cotton salk. Can. J. Microbiol. 44 (1998) 676-680
9. Dubois M., Gilles K.A., Hamilton J.K., Rebes P.A., and Smith F. Colorimetric method for determination of sugars and related substances. Anal. Chem. 28 (1956) 350
10. Provencher S.W. CONTIN: a general purpose constrained regularization program for inverting noisy linear algebraic and integral equations. Comput. Phys. Commun. 27 (1982) 229-242
11. Provencher S.W. A constrained regularization method for inverting data represented by linear algebraic or integral equations. Comput. Phys. Commun. 27 (1982) 213-227
12. Schwartz B., Lamprecht S.A., Polak-Charcon S., Niv Y., and Kim Y.S. Induction of the differentiated phenotype in human colon cancer cell is associated with the attenuation of subcellular tyrosine phosphorylation. Oncol. Res. 7 (1995) 277-287
13. Livny O., Kaplan I., Reifen R., Polak-Charcon S., Madar Z., and Schwartz B. Oral cancer cells differ from normal oral epithelial cells in tissue like organization and in response to lycopene treatment: an organotypic cell culture study. Nutr. Cancer 47 (2003) 195-209
14. Cheng A.C., Huang T.C., Lai C.S., and Pan M.H. Induction of apoptosis by luteolin through cleavage of Bcl-2 family in human leukemia HL-60 cells. Eur J. Pharmacol. 509 1 (2005) 1-10
15. Lifshitz S., Lamprecht S.A., Benharroch D., Prinsloo I., Polak-Charcon S., and Schwartz B. Apoptosis (programmed cell death) in colonic cells: from normal to transformed stage. Cancer Lett. 163 2 (2001) 229-238
16. Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 149 1-3 (2004) 19-23
17. Lee Y.L., Kim H.J., Lee M.S., Kim J.M., Han J.S., Hong E.K., et al. Oral administration of agaricus blazei (H1 strain) inhibited tumor growth in a sarcoma 180 inoculation model. Exp. Anim. 52 5 (2003) 371-375
18. Kidd P.M. The use of mushroom glucans and proteoglycans in cancer treatment. Altern. Med. Rev. 5 1 (2000) 4-27
19. Zusman I., Reifen R., Livni O., Smirnoff P., Gurevich P., Sandler B., et al. Role of apoptosis, proliferating cell nuclear antigen and p53 protein in chemically induced colon cancer in rats fed corncob fiber treated with thefungus Pleurotus ostreatus. Anticancer Res. 17 (1997) 2105-2113
20. Reis R.A., Tischer C.A., Gorin P.A.J., and Iacomini M. A new pullulan and a branched (1→3)-, (1→6)-linked β-glucan from the lichenised ascomycete teloschistes flavicans. FEMS Microbiol. Lett. 210 (2002) 1-5
21. Cordeiro L.M.C., Worgotter E.S., Gorin P.A.J., and Iacomini M. Comparative studies of the polysaccharides from species of the genus Ramalina-lichenized fungi of three distinct habitats. Phytochemistry 63 (2003) 967-975
22. Mondal S., Chakraborty I., Pramanik M., Rout D., and Islam S.S. Structural studies of water-soluble polysaccharides of an edible mushroom, termitomyces eurhizus. A reinvestigation. Carbohydr. Res. 339 (2004) 1135-1140
23. Zhang P., Zhang L., and Cheng S. Solution properties of an α-(1→3)-d-glucan from Lentinus edodes and its sulfated derivatives. Carbohydr. Res. 337 (2002) 155-160
24. Chiarugi V., and Ruggiero M. Role of three cancer 'master genes' p53, bcl2 and c-myc on the apoptotic process. Tumori 82 3 (1996) 205-209
25. Harada H., and Grant S. Apoptosis regulators. Rev. Clin. Exp. Hematol. 7 2 (2003) 117-138
26. Harnois C., Demers M.J., Bouchard V., Vallee K., Gagne D., Fujita N., et al. Human intestinal epithelial crypt cell survival and death: complex modulations of Bcl-2 homologs by Fak, PI3-K/Akt-1, MEK/Erk, and p38 signaling pathways. J. Cell Physiol. 198 2 (2004) 209-222