The effects of Musk T on peroxisome proliferator-activated receptor [PPAR]-α activation, epidermal skin homeostasis and dermal hyaluronic acid synthesis

Archives of Dermatological Research

Volumn 298, Issue 6, 2006, Pages 273-282

  Kim, Seung Hun ^a   Nam, Gae Won ^a   Lee, Hae Kwang ^a   Moon, Seong Joon ^a   Chang, Ih Seop ^a  

^a AmorePacific Corporation   (South Korea)

Author keywords

Homeostasis; Hyaluronan; Musk; Peroxisome proliferators activated receptors; Skin

Indexed keywords

1,4 DIOXACYCLOHEPTADECANE 5,17 DIONE; ASTRATONE; BETA GLUCOCEREBROSIDASE; ENZYME; ETHYLENE BRASSYLATE; HYALURONIC ACID; INVOLUCRIN; LIGAND; MUSK; PERFUME; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PIRINIXIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG ACTIVATION; EPIDERMIS CELL; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; EPIDERMIS; ETHERS, CYCLIC; FATTY ACIDS, MONOUNSATURATED; FEMALE; FIBROBLASTS; GLUCURONOSYLTRANSFERASE; HOMEOSTASIS; HUMANS; HYALURONIC ACID; INTERMEDIATE FILAMENT PROTEINS; KERATINOCYTES; MICE; MICE, HAIRLESS; MICE, INBRED HRS; PPAR ALPHA; PROTEIN PRECURSORS; RNA, MESSENGER;

EID: 33749260361     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-006-0684-y     Document Type: Article

References (50)

1. Akiyama H, Saito M, Qiu G, Toida T, Imanari T (1994) Analytical studies on hyaluronic acid synthesis by normal human epidermal keratinocytes cultured in a serum-free medium. Biol Pharm Bull 17:361-364
2. Berger A, Monnard I, Baur M, Charbonnet C, Safonova I, Jomard A (2002) Epidermal anti-inflammatory properties of 5,11,14 20:3: effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation. Lipids Health Dis I: 5, DOI 10.1186/1476-511X-1-5
3. Chen W, Yang CC, Sheu HM, Seltmann H, Zouboulis CC (2003) Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J Invest Dermatol 121:441-447, DOI 10.1046/j.1523-1747.2003.12411.x
4. Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20:649-688
5. DiRenzo J, Soderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Horlein A, Rosenfeld MG, Glass CK (1997) Peroxisome proliferators activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Mol Cell Biol 17:2166-2176
6. Edward M, Oliver RF (1983) Changes in the synthesis, distribution and sulphation of glycosaminoglycans of cultured human skin fibroblasts upon ascorbate feeding. J Cell Sci 64:245-254
7. Forman BM, Chen J, Evans RM (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94(9):4312-4317
8. Fukuda K, Takayama M, Ueno M, Oh M, Asada S, Kumano F, Tanaka S (1997) Hyaluronic acid inhibits interleukin-1-induced superoxide anion in bovine chondrocytes. Inflamm Res 46:114-117
9. Ghersetich I, Lotti T, Campanile G, Grappone C, Dini G (1994) Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol 33:119-122
10. Hanley K, Komuves LG, Bass NM, He SS, Jiang Y, Crumrine D, Appel R, Friedman M, Bettencourt J, Min K, Elias PM, Williams ML, Feingold KR (1999) Fetal epidermal differentiation and barrier development in vivo is accelerated by nuclear hormone receptor activators. J Invest Dermatol 113:788-795, DOI 10.1046/j.1523-1747.1999.00743.x
11. Holleran WM, Takagi Y, Imokawa G, Jackson S, Lee JM, Elias PM (1992) β-Glucocerebrosidase activity in murine epidermis: characterization and localization in relation to differentiation. J Lipid Res 33(8):1201-1209
12. Isseman I, Green S (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 247:645-650, DOI 10.1038/347645a0
13. Kang HY, Chung E, Lee M, Cho Y, Kang WH (2004) Expression and function of peroxisome proliferator-activated receptors in human melanocytes. Br J Dermatol 150:462-468, DOI 10.1111/j.1365-2133.2004.05844.x
14. Karvinen S, Pasonen-Seppanen S, Hyttinen JM, Pienimaki JP, Toronen K, Jokela TA, Tammi MI, Tammi R (2003) Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthase 2 and 3. J Biol Chem 278(49):49495-49504, DOI 10.1074/jbc.M310445200
15. Kim S, Kang BY, Cho SY, Sung DS, Chang HK, Yeom MH, Kim DH, Sim YC, Lee YS (2004) Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin. Biochem Biophys Res Comm 316:348-355, DOI 10.1016/j.bbrc.2004.02.046
16. King IA (1984) Increased epidermal hyaluronic acid synthesis caused by four retinoids. Br J Dermatol 110:607-608, DOI 10.1007/s102270000126
17. Kippenberger S, Loitsch SM, Grundmann-Kollmann M, Simon S, Dang TA, Hardt-Weinelt K, Kaufmann R, Bernd A (2001) Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light- induced inflammation. J Invest Dermatol 117:1430-1436, DOI 10.1046/j.0022-202x. 2001.01537.x
18. Kliewer SA, Lehmann JM, Willson TM (1999) Orphan nuclear receptors: shifting endocrinology into reverse. Science 284:757-760, DOI: 10.1126/science.284.5415.757
19. Kliewer SA, Sundseth SS, Jones SA, Brown PJ, Wisely GB, Koble CS, Devchand P, Wahli W, Wilson TM, Lenhard JM, Lehmann JM (1997) Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc Natl Acad Sci USA 94(9):4318-4323
20. Komuves LG, Hanley K, Lefebvre AM, Man MQ, Ng DC, Bikle DD, Williams ML, Elias PM, Auwerx J, Feingold KR (2000) Stimulation of PPAR alpha promotes epidermal keratinocyte differentiation in vivo. J Invest Dermatol 115:353-360, DOI 10.1046/j.1523-1747.2000.00073.x
21. Komuves LG, Hanley K, Man MQ, Elias PM, Williams ML, Feingold KR (2000) Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPAR a activators restores tissue homeostasis. J Invest Dermatol 115:361-367, DOI 10.1046/j.1523-1747.2000.00076.x
22. Krey G, Braissant O, L'Horset F, Kalkhoven E, Perroud M, Parker MG, Wahli W (1997) Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11(6):779-791
23. Kuenzli S, Saurat JH (2003) Peroxisome proliferator-activated receptors in cutaneous biology. Br J Dermatol 149:229-236, DOI 10.1046/j.1365-2133.2003. 05532.x
24. Kuenzli S, Saurat JH (2004) Peroxisome proliferator-activated receptors as new molecular targets in psoriasis. Curr Drug Targets-Inflamm Allergy 3:205-211
25. Lamberg SI, Stoolmiller AC (1974) Glycosaminoglycans. A biochemical and clinical review. J Invest Dermatol 63:433-449
26. Manuskiatti W, Maibach HI (1996) Hyaluronic acid and Skin: wound healing and aging. Int J Dermatol 35:539-544
27. Meyer LJ, Stern R (1994) Age-dependent changes of hyaluronan in human skin. J Invest Dermatol 102:385-389
28. Moczar M, Robert L (1993) Stimulation of cell proliferation by hyaluronidase during in vitro aging of human skin fibroblasts. Exp Gerontol 28:59-68
29. Muga SJ, Thuillier P, Pavone A, Rundhaug JE, Boeglin WE, Jisaka M, Brash AR, Fischer SM (2000) 8S-Lipoxygenase products activate peroxisome proliferator-activated receptor a and induce differentiation in murine keratinocyte. Cell Growth Differ 11:447-454
30. Rivier M, Castiel I, Safonova I, Ailhaud G, Michel S (2000) Peroxisome proliferator-activated receptor-α enhances lipid metabolism in a skin equivalent model. J Invest Dermatol 114:681-687, DOI 10.1046/j.1523-1747.2000. 00939.x
31. Rosenfield RL, Deplewski D, Greene ME (2000) Peroxisome proliferator-activated receptors and skin development. Horm Res 54:269-274, DOI 10.1159/000053270
32. Saarni H, Hopsu-Havu VK (1978) The decrease of hyaluronate synthesis by anti-inflammatory steroids in vitro. Br J Dermatol 98:445-449
33. Saarni H, Jalkanen M, Hopsu-Havu VK (1980) Effects of five anti-inflammatory steroids on collagen and glycosaminoglycan synthesis in vitro. Br J Dermatol 103:167-173
34. Saarni H, Tammi M, Doherty NS (1978) Decreased hyaluronic acid synthesis, a sensitive indicator of cortisol action on fibroblast. J Pharm Pharmacol 30:200-201
35. Sakai S, Sayo T, Kodama S, Inoue S (1999) N-Methyl-L-Serine stimulates hyaluronan production in human skin fibroblasts. Skin Pharmacol Physiol 12:276-283, DOI: 10.1159/000066253
36. Sakai S, Yasuda R, Sayo T, Ishikawa O, Inoue S (2000) Hyaluronan exists in the normal stratum corneum. J Invest Dermatol 114:1184-1187, DOI 10.1046/j.1523-1747.2000.00992.x
37. Sayo T, Sakai S, Inoue S (2002) Synergistic effect of N-acetylglucosamine and retinoids on hyaluronan production in human keratinocytes. Skin Pharmacol Physiol 17:77-83, DOI 10.1159/000076017
38. Sayo T, Sugiyama Y, Takahashi Y, Ozawa N, Sakai S, Ishikawa O, Tamura M, Inoue S (2002) Hyaluronan synthase 3 regulates hyaluronan synthesis in cultured human keratinocytes. J Invest Dermatol 118:43-48, DOI 10.1046/j.0022-202x.2001. 01613.x
39. Schoonjans K, Staels B, Auwerx J (1996) Role of the peroxisome proliferators-activated receptor in mediating the effects of fibrates and fatty acids on gene expression. J Lipid Res 37:907-925
40. Sheu MY, Fowler AJ, Kao J, Schmuth M, Schoonjans K, Auwerx J, Fluhr JW, Man MQ, Elias PM, Feingold KR (2002) Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. J Invest Dermatol 118:94-101, DOI 10.1046/j.0022-202x.2001. 01626.x
41. Smith KJ, Dipreta E, Skelton H (2001) Peroxisomes in Dermatology. Part I. J Cutan Med Surg 5:231-243, DOI 10.1007/s102270000026
42. Smith KJ, Dipreta E, Skelton H (2001) Peroxisomes in Dermatology. Part II. J Cutan Med Surg 5:315-322
43. Sugiyama Y, Shimada A, Sayo T, Sakai S, Inoue S (1998) Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-b upregulates their expression in cultured human skin cells. J Invest Dermatol 110:116-121
44. Tammi R, Jansen CT, Tammi M (1985) Effects of retinoic acid on adult human epidermis in whole skin organ culture. Arch Dermatol Res 277:276-283
45. Tammi R, Ripellino JA, Margolis RU, Maibach HI, Tammi M (1989) Hyaluronate accumulation in human epidermis treated with retinoic acid in skin organ culture. J Invest Dermatol 92:326-332
46. Tammi R, Ripellino JA, Margolis RU, Tammi M (1988) Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycans as a specific probe. J Invest Dermatol 90:412-414
47. Tammi R, Tammi M (1986) Influence of retinoic acid on the ultrastructure and hyaluronic acid synthesis of adult human epidermis in whole skin organ culture. J Cell Physiol 126:389-398
48. Uzuka M, Nakajima K, Ohta S, Mori Y (1980) The mechanism of estrogen-induced increase in hyaluronic acid biosynthesis, with special reference to estrogen receptor in the mouse skin. Biochim Biophys Acta 627:199-206
49. Vamec J, Latruffe N (1999) Medical significance of peroxisome proliferator-activated receptors. Lancet 354:141-148, DOI 10.1016/S0140-6736(98) 10364-1
50. Wahli W (2002) Peroxisome proliferator-activated receptors (PPARs): from metabolic control to epidermal wound healing. Swiss Med Wkly 132:83-91