Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 609, Issue 2, 2006, Pages 117-128

  Chakraborty, Tridib ^a   Pandey, Nirupama ^a   Chatterjee, Amrita ^a   Ghosh, Balaram ^a   Rana, Basabi ^b   Chatterjee, Malay ^a  

^a JADAVPUR UNIVERSITY   (India)

^b Texas A and M University   (United States)

Author keywords

8 OHdG; Chromosomal aberrations; DNA strand breaks; DNA protein crosslinks; Hepatocarcinogenesis; Vanadium

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; AMMONIUM VANADATE; CLASTOGEN; DIETHYLNITROSAMINE; DNA; TRACE METAL; VANADIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHROMOSOME ABERRATION; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; LIVER CARCINOGENESIS; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; SPECTROFLUOROMETRY;

ANIMALS; ANTIMUTAGENIC AGENTS; CHROMOSOME ABERRATIONS; DEOXYGUANOSINE; DIETHYLNITROSAMINE; DNA DAMAGE; LIVER NEOPLASMS, EXPERIMENTAL; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; VANADATES; VANADIUM;

EID: 33749258161     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.04.023     Document Type: Article

References (69)

1. Farber E. The multistep nature of cancer development. Cancer Res. 44 (1984) 4217-4223
2. Tatematsu M., Nagamine Y., and Farber E. Stable phenotypic expression of glutathione-S-transferase placental type and unstable phenotypic expression of γ-glutamyl transpeptidase in rat liver preneoplastic and neoplastic lesions. Carcinogenesis 9 (1988) 215-220
3. Fenech M., and Ferguson L.R. Vitamins/minerals and genomic stability in humans. Mutat. Res. 475 (2001) 1-6
4. French R.J., and Jones P.J. Role of vanadium in nutrition: metabolism, essentiality and dietary consideration. Life Sci. 52 (1993) 339-346
5. Hopkins Jr. L.L., and Mohr.F H.E. The biological essentiality of vanadium. In: Mertz W., and Cornatzer W.E. (Eds). Newer Trace Elements in Nutrition (1971), Marcel Dekker, New York 195-213
6. Stern A., Yin X., Tsang S.S., Davidson A., and Moon J. Vanadium as a modulator of cellular regulatory cascades and oncogene expression. Biochem. Cell Biol. 71 (1993) 103-112
7. Kopf-Maier P., and Kopf H. Transition and main-group metal cyclopentadienyl complexes: preclinical studies on a series of antitumor agents of different structural type. Struct. Bond. 70 (1988) 103-185
8. Murthy M.S., Rao L.N., Kuo L.Y., Toney J.H., and Marks T.J. Antitumor and toxicologic properties of the organometallic anticancer agent vanadocene dichloride. Inorg. Chim. Acta 152 (1988) 117-124
9. Sakurai H., Tamura H., and Okatani K. Mechanism for a new antitumor vanadium complex: hydroxyl radical dependent DNA cleavage by 1,10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide. Biochem. Biophys. Res. Commun. 206 (1995) 133-137
10. Navara C.S., Benyumov A., Vassilev A., Narla R.K., Ghosh P., and Uckun F.M. Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells. Anticancer Res. 12 (2001) 369-376
11. D'Cruz O.J., and Uckun F.M. Metvan: a novel oxovanadium(IV) complex with broad spectrum anticancer activity. Expert Opin. Investig. Drugs 11 (2002) 1829-1836
12. Scrivens P.J., Alaoui-Jamali M.A., Giannini G., Wang T., Loignon M., Batist G., and Sandor V.A. Cdc25A-inhibitory properties and antineoplastic activity of bisperoxovanadium analogues. Mol. Cancer Ther. 2 (2003) 1053-1059
13. Bishayee A., and Chatterjee M. Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital. Br. J. Cancer 71 (1995) 1214-1220
14. Bishayee A., and Chatterjee M. Inhibition of altered liver cell foci and persistent nodule growth by vanadium during diethylnitrosamine-induced hepatocarcinogenesis in rats. Anticancer Res. 15 (1995) 455-461
15. Bishayee A., Roy S., and Chatterjee M. Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis. Oncol. Res. 11 (1999) 41-53
16. 3 inhibit diethylnitrosamine induced rat liver carcinogenesis. Chem. Biol. Interact. 128 (2000) 1-18
17. 3 inhibit placental glutathione S-transferase positive foci in rat liver carcinogenesis. Life Sci. 68 (2000) 217-231
18. Bishayee A., and Chatterjee M. Time course effects of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity. Biol. Trace Elem. Res. 48 (1995) 275-285
19. Zaparowska H., and Wasilewski W. Some selected peripheral blood and haemopoietic system indices in Wistar rats with chronic vanadium intoxication. Comp. Biochem. Physiol. 93C (1989) 175-180
20. Zaparowska H., Wasilewski W., and Slotwinska M. Effects of chronic vanadium administration in drinking water to rats. Biometals 6 (1993) 3-10
21. Meyerovitch J., Farfel Z., Sack J., and Shechter Y. Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. J. Biol. Chem. 262 (1987) 6658-6662
22. Lindahl T. Instability and decay of the primary structure of DNA. Nature 362 (1993) 709-715
23. Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res. 387 (1997) 147-163
24. Nakae D., Kobayashi Y., Akai H., Andoh N., Satox H., Ohashi K., Tsutsumi M., and Konishi Y. Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. Cancer Res. 57 (1997) 1281-1287
25. Olive P.L., Wlodek D., Duran R.E., and Banath J.P. Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp. Cell Res. 198 (1992) 259-267
26. Land H., Parada L.F., and Weinberg R.A. Cellular oncogenes and multistep carcinogenesis. Science 222 (1983) 771-778
27. Dahlaus M., and Appel K.E. N-Nitrosodimethylamine, N-nitrosodiethylamine, and N-nitrosomorpholine fail to generate 8-hydroxy-2′-deoxyguanosine in liver DNA of male F344 rats. Mutat. Res. 285 (1993) 295-302
28. Park J.W., Cundi K.C., and Ames B.N. Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection. Carcinogenesis 10 (1989) 827-832
29. Shen H.M., Ong C.N., Lee B.L., and Shi C.Y. Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA. Carcinogenesis 16 (1995) 419-422
30. Zhitkovich A., and Costa M.A. A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. Carcinogenesis 13 (1992) 1485-1489
31. Horiuchi T., Ito K., Suzuki M., and Umeda M. Sensitive induction of chromosome aberration in the in-vivo liver cells of rats by N-nitrosodiethylamine. Mutat. Res. 140 (1984) 181-185
32. Schroeder H.A., Mitchener M., and Nason A.P. Zirconium, niobium, antimony, vanadium and lead in rats: life term studies. J. Nutr. 100 (1970) 59-68
33. Dai S., Vera E., and McNeill J.H. Lack of haematological effect of oral vanadium treatment in rats. Pharmacol. Toxicol. 76 (1995) 263-268
34. Parker E.D.R., and Sharma R.P. Accumulation and depletion of vanadium in selected tissues of rats treated with vanadyl sulfate and sodium orthovanadate. J. Environ. Pathol. Toxicol. 2 (1978) 235-245
35. Diamond E.G., Caravaca J., and Benchimol A. Vanadium. Excretion, toxicity, lipid effect in man. Am. J. Clin. Nutr. 12 (1963) 49-53
36. Schroeder H.A., Balassa J.J., and Tipton I.H. Abnormal trace metals in man-vanadium. J. Chron. Dis. 16 (1963) 1047-1071
37. Cohen N., Halberstam M., Shlimovich P., Chang C.J., Shamoon H., and Rossetti L. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin. Invest. 95 (1995) 2501-2509
38. Goldfine A.B., Simoson D.C., Folli F., Patti M.E., and Khan C.R. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J. Clin. Endocrinol. Metab. 80 (1995) 3311-3320
39. Smith J.B. Vanadium ions stimulate DNA synthesis in Swiss mouse 3T3 and 3T6 cells. Proc. Natl. Acad. Sci. U.S.A. 80 (1983) 6162-6166
40. Jones T.R., and Reid T.W. Sodium orthovanadate stimulation of DNA synthesis in Nakano mouse lens epithelial cells in serum free medium. J. Cell Physiol. 124 (1984) 199-205
41. Hanauske U., Hanauske A.R., Marshall M.H., Muggia V.M., and Von Hoff D.D. Biphasic effect of vanadium salts on in vitro tumor colony growth. Int. J. Cell Clon. 5 (1987) 170-178
42. Cohen M.D., Klein C.B., and Costa M. Forward mutations and DNA-protein crosslinks induced by ammonium metavanadate in cultured mammalian cells. Mutat. Res. 269 (1992) 141-148
43. Floyd R.A. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11 (1990) 1447-1450
44. Cattley R.C., and Glover S.E. Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization. Carcinogenesis 14 (1993) 2495-2499
45. Kato T., Hasegawa R., Nakae D., Hirose M., Yamao M., Kobayashi Y., Konishi Y., Ito N., and Shirai T. Dose-dependent induction of 8-hydroxyguanine and prneoplastic foci in rat liver by food-derived carcinogen, 2-amino-3,8-dimethylimidazo[4,5-f]quinoline at low dose levels. Jpn. J. Cancer Res. 87 (1996) 127-133
46. Jackson S.P. Sensing and repairing DNA double-strand breaks. Carcinogenesis 23 (2002) 687-696
47. Vu V., Moller M.E., Grantham P.H., Wirth P.J., and Thorgeirsson S.S. Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene. Carcinogenesis 6 (1985) 45-52
48. Sugiyama M., Wang X.-W., and Costa M. Comparison of DNA lesions and cytotoxicity induced by calcium chromate in human, mouse, and hamster cell lines. Cancer Res. 46 (1986) 4547-4551
49. Oleinick N.L., Chiu S.-M., Ramakrishnan N., and Xue L.-Y. The formation, identification, and significance of DNA-protein crosslinks in mammalian cells. Br. J. Cancer 55 (1987) 135-140
50. Minko I.G., Zou Y., and Lloyd R.S. Incision of DNA-protein crosslinks by UvrABC nuclease suggests a potential repair pathway involving nucleotide excision repair. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 1905-1909
51. Ciechanover A. The ubiquitin-proteosome pathway: on protein death and cell life. EMBO J. 17 (1998) 7151-7160
52. Grover S., and Fisher P. Cytogenetic studies in Sprague-Dawley rats during the administration of carcinogen nitroso compound-diethynitrosamine. Eur. J. Cancer 7 (1971) 77-82
53. Holeck B.U., Kerler R.R., and Rabes H.M. Chromosomal analysis of a diethylnitrosamine-induced tumorigenic and a non-tumorigenic rat liver cells. Cancer Res. 49 (1989) 3024-3028
54. Dave B.J., Hsu T.C., Hong W.K., and Pathak S. Nonrandom distribution of mutagen-induced chromosome breaks in lymphocytes of patients with different malignancies. Int. J. Oncol. 5 (1994) 733-740
55. Wagner E.D., and Plewa M.J. Induction of somatic mutations in tradescantia clone 4430 by three phenylenediamine isomers and the antimutagenic mechanisms of diethyldithiocarbamate and ammonium meta-vanadate. Mutat. Res. 306 (1994) 165-172
56. Floyd R.A., West M.S., Eneff K.L., Hogsett W.E., and Tingey D.T. Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA. Arch. Biochem. Biophys. 262 (1988) 266-272
57. Keyer K., and Imlay J.A. Superoxide accelerates DNA damage by elevating free-iron levels. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 13635-13640
58. Sabbioni E., Pozzi G., Devos S., Pintat A., Casella L., and Fischbach M. The intensity of vanadium (V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-dependent bioreduction to vanadium (IV). Carcinogenesis 14 (1993) 2565-2568
59. Kanna P.S., Mahendrakumar C.B., Indira B.N., Srivastawa S., Kalaiselvi K., Elayaraja T., and Chatterjee M. Chemopreventive effects of vanadium towards 1,2 dimethylhydrazine induced genotoxicity and preneoplastic lesions in rat colon. Environ. Mol. Mutagen. 44 (2004) 113-118
60. Sai K., Umemura T., Takagi A., Hasegawa R., and Kurokawa Y. The protective role of glutathione, cysteine and vitamin C against oxidative DNA damage induced in rat kidney by potassium bromate. Jpn. J. Cancer Res. 83 (1992) 45-51
61. Sato M., Kitahori Y., Nakagawa Y., Konishi N., Cho M., and Hiasa Y. Formation of 8-hydroxydeoxyguanosine in rat kidney DNA after administration of N-ethyl-N-hydroxyethylnitrosamine. Cancer Lett. 124 (1998) 111-118
62. Chung F.L., Komninou D., Zhang L., Nath R., Pan J., Amin S., and Richie J. Glutathione depletion enhances the formation of endogenous cyclic DNA adducts derived from t-4-hydroxy-2-nonenal in rat liver. Chem. Res. Toxicol. 18 (2005) 24-27
63. 51V 2-D NMR for studies of kinetic exchange between vanadate oligomers. J. Am. Chem. Soc. 112 (1990) 2901-2908
64. Hamilton E.E., and Wilker J.J. Inhibition of DNA alkylation damage with inorganic salts. J. Biol. Inorg. Chem. 9 (2004) 894-902
65. Kasprzak K.S., and Waalkes M.P. The role of calcium, magnesium, and zinc in carcinogenesis. Adv. Exp. Med. Biol. 206 (1986) 497-515
66. Bohr V.A., and Dianov G.L. Oxidative DNA damage processing in nuclear and mitochondrial DNA. Biochimie 81 (1999) 155-160
67. Boiteux S., and Radicella J.P. Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress. Biochimie 81 (1999) 59-67
68. Kihlman B.A., Hansson K., and Andersson H.C. The effects of post-treatments with caffeine during S and G2 on the frequencies of chromosomal aberrations induced by thiotepa in root tips of Vicia fava. Environ. Exp. Bot. 20 (1982) 271-286
69. Zhang Z., Huang C., Li J., and Shi X. Vanadate-induced cell growth arrest is p53-dependent through activation of p21 in C141 cells. J. Inorg. Biochem. 89 (2002) 142-148