-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L., and Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25 (1961) 585-621
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA 92 (1995) 9363-9367
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
-
3
-
-
0036060157
-
Expression profiles of p53-, p16(INK4a)-, and telomere-regulating genes in replicative senescent primary human, mouse, and chicken fibroblast cells
-
Kim H., You S., Farris J., Kong B.W., Christman S.A., Foster L.K., et al. Expression profiles of p53-, p16(INK4a)-, and telomere-regulating genes in replicative senescent primary human, mouse, and chicken fibroblast cells. Exp. Cell Res. 272 (2002) 199-208
-
(2002)
Exp. Cell Res.
, vol.272
, pp. 199-208
-
-
Kim, H.1
You, S.2
Farris, J.3
Kong, B.W.4
Christman, S.A.5
Foster, L.K.6
-
4
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120 (2005) 513-522
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
5
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley C.B., Futcher A.B., and Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature 345 (1990) 458-460
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
6
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
Shay J.W., Pereira-Smith O.M., and Wright W.E. A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res. 196 (1991) 33-39
-
(1991)
Exp. Cell Res.
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
7
-
-
0034682721
-
Cellular senescence: mitotic clock or culture shock?
-
Sherr C.J., and DePinho R.A. Cellular senescence: mitotic clock or culture shock?. Cell 102 (2000) 407-410
-
(2000)
Cell
, vol.102
, pp. 407-410
-
-
Sherr, C.J.1
DePinho, R.A.2
-
8
-
-
0027359827
-
A potential mediator of p53 tumor suppression
-
el-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., et al. A potential mediator of p53 tumor suppression. Cell 75 (1993) 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
9
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., and Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80 (1995) 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
10
-
-
0034640281
-
A BH3-Only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E., Ohki R., Murasawa H., Nemoto J., Shibue T., Yamashita T., et al. A BH3-Only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288 (2000) 1053-1058
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
-
11
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden K.H., and Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer 2 (2002) 594-604
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
12
-
-
0037317840
-
Inhibiting the p53-MDM2 interaction: an important target for cancer therapy
-
Chene P. Inhibiting the p53-MDM2 interaction: an important target for cancer therapy. Nat. Rev. Cancer 3 (2003) 102-109
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 102-109
-
-
Chene, P.1
-
13
-
-
0035808446
-
Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3
-
Servant M.J., ten Oever B., LePage C., Conti L., Gessani S., Julkunen I., et al. Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3. J. Biol. Chem. 276 (2001) 355-363
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 355-363
-
-
Servant, M.J.1
ten Oever, B.2
LePage, C.3
Conti, L.4
Gessani, S.5
Julkunen, I.6
-
14
-
-
0036199090
-
Recognition of the measles viral nucleocapsid as a mechanism of IRF-3 activation
-
tenOever B.R., Servant M.J., Grandvaux N., Lin R., and Hiscott J. Recognition of the measles viral nucleocapsid as a mechanism of IRF-3 activation. J. Virol. 76 (2002) 3659-3669
-
(2002)
J. Virol.
, vol.76
, pp. 3659-3669
-
-
tenOever, B.R.1
Servant, M.J.2
Grandvaux, N.3
Lin, R.4
Hiscott, J.5
-
15
-
-
0037022639
-
Interferon regulatory factor-3 is an in vivo target of DNA-PK
-
Karpova A.Y., Trost M., Murray J.M., Cantley L.C., and Howley P.M. Interferon regulatory factor-3 is an in vivo target of DNA-PK. Proc. Natl Acad. Sci. USA 99 (2002) 2818-2823
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2818-2823
-
-
Karpova, A.Y.1
Trost, M.2
Murray, J.M.3
Cantley, L.C.4
Howley, P.M.5
-
16
-
-
0037105715
-
In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors
-
Duguay D., Mercier F., Stagg J., Martineau D., Bramson J., Servant M., et al. In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors. Cancer Res. 62 (2002) 5148-5152
-
(2002)
Cancer Res.
, vol.62
, pp. 5148-5152
-
-
Duguay, D.1
Mercier, F.2
Stagg, J.3
Martineau, D.4
Bramson, J.5
Servant, M.6
-
17
-
-
0037674586
-
Oncogenic potential of a dominant negative mutant of interferon regulatory factor 3
-
Kim T.Y., Lee K.H., Chang S., Chung C., Lee H.W., Yim J., et al. Oncogenic potential of a dominant negative mutant of interferon regulatory factor 3. J. Biol. Chem. 278 (2003) 15272-15278
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15272-15278
-
-
Kim, T.Y.1
Lee, K.H.2
Chang, S.3
Chung, C.4
Lee, H.W.5
Yim, J.6
-
18
-
-
18644376284
-
IRF3 and NF-kB mediate a TLR4-specific gene program
-
Doyle S.E., Vaidya S.A., O'Connell R., Dadgostar H., Dempsey P.W., Wu T.-T., et al. IRF3 and NF-kB mediate a TLR4-specific gene program. Immunity 17 (2002) 251-263
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.E.1
Vaidya, S.A.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.W.5
Wu, T.-T.6
-
19
-
-
0041662272
-
Integration of IFN-α/β signalling to p53 responses in tumor suppression and antiviral defense
-
Takaoka A., Hayakawa S., Yanai H., Stoiber D., Negishi H., Kikuchi H., et al. Integration of IFN-α/β signalling to p53 responses in tumor suppression and antiviral defense. Nature 424 (2003) 516-523
-
(2003)
Nature
, vol.424
, pp. 516-523
-
-
Takaoka, A.1
Hayakawa, S.2
Yanai, H.3
Stoiber, D.4
Negishi, H.5
Kikuchi, H.6
-
20
-
-
0033130010
-
Nucleolar arf sequesters Mdm2 and activates p53
-
Weber J.D., Taylor L.J., Roussel M.F., Sherr C.J., and Bar-Sagi D. Nucleolar arf sequesters Mdm2 and activates p53. Nat. Cell Biol. 1 (1999) 20-26
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 20-26
-
-
Weber, J.D.1
Taylor, L.J.2
Roussel, M.F.3
Sherr, C.J.4
Bar-Sagi, D.5
-
21
-
-
0034306019
-
The function of PML in p53-dependent apoptosis
-
Guo A., Salomoni P., Luo J., Shih A., Zhong S., Gu W., et al. The function of PML in p53-dependent apoptosis. Nat. Cell Biol. 2 (2000) 730-736
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 730-736
-
-
Guo, A.1
Salomoni, P.2
Luo, J.3
Shih, A.4
Zhong, S.5
Gu, W.6
-
22
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
-
Freeman D.J., Li A.G., Wei G., Li H.H., Kertesz N., Lesche R., et al. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell 3 (2003) 117-130
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, G.3
Li, H.H.4
Kertesz, N.5
Lesche, R.6
-
23
-
-
3242726103
-
Loss of the tumor suppressor PML in human cancers of multiple histologic origins
-
Bernardi R., Scaglioni P.P., Bergmann S., Horn H.F., Vousden K.H., and Pandolfi P.P. Loss of the tumor suppressor PML in human cancers of multiple histologic origins. Nat. Cell Biol. 6 (2004) 665-672
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 665-672
-
-
Bernardi, R.1
Scaglioni, P.P.2
Bergmann, S.3
Horn, H.F.4
Vousden, K.H.5
Pandolfi, P.P.6
-
24
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
Dornan D., Wertz I., Shimizu H., Arnott D., Frantz G.D., Dowd P., et al. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429 (2004) 86-92
-
(2004)
Nature
, vol.429
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
Arnott, D.4
Frantz, G.D.5
Dowd, P.6
|