Expression mapping of tetracycline-responsive prion protein promoter: Digital atlasing for generating cell-specific disease models

NeuroImage

Volumn 33, Issue 2, 2006, Pages 449-462

  Boy, Jana ^a   Leergaard, Trygve B ^b   Schmidt, Thorsten ^a   Odeh, Francis ^b   Bichelmeier, Ulrike ^a   Nuber, Silke ^a   Holzmann, Carsten ^c   Wree, Andreas ^c   Prusiner, Stanley B ^d   Bujard, Hermann ^e   Riess, Olaf ^a   Bjaalie, Jan G ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF ROSTOCK   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Brain atlas; Double transgenic mice; Huntington's disease; Inducible mouse model; Neuroinformatics; Parkinson's disease; Prion protein; PrP; Spinocerebellar ataxia

Indexed keywords

BETA GALACTOSIDASE; PRION PROTEIN; TETRACYCLINE;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL LABELING; CELL SHAPE; CELL SIZE; CELLULAR DISTRIBUTION; CEREBELLUM; CONTROLLED STUDY; CYTOARCHITECTURE; FEMALE; GENE EXPRESSION; GENE MAPPING; GENE TARGETING; GLIA CELL; GLOBUS PALLIDUS; HIPPOCAMPUS; INTERNEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; PURKINJE CELL; REPORTER GENE; SUBSTANTIA NIGRA; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALS; AUTOMATION; BETA-GALACTOSIDASE; BRAIN; BRAIN MAPPING; CEREBELLUM; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY; PRIONS; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; SUBSTANTIA NIGRA; USER-COMPUTER INTERFACE;

EID: 33749237478     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2006.05.055     Document Type: Article

References (68)

1. C) immunocytochemistry and expression of the green fluorescent protein reporter gene under control of the bovine PrP gene promoter in the mouse brain. J. Comp. Neurol. 473 (2004) 244-269
2. Bak I.J. The ultrastructure of the substantia nigra and caudate nucleus of the mouse and the cellular localization of catecholamines. Exp. Brain Res. 3 (1967) 40-57
3. Bard J.B. Anatomics: the intersection of anatomy and bioinformatics. J. Anat. 206 (2005) 1-16
4. Baron U., Freundlieb S., Gossen M., and Bujard H. Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res. 23 (1995) 3605-3606
5. Bjaalie J.G. Localization in the brain: new solutions emerging. Nat. Neurosci., Rev. 3 (2002) 322-325
6. Bjaalie J.G., and Leergaard T.B. Three-dimensional computerized reconstruction from serial sections: cells populations, regions, and whole brain. In: Zaborszky L., Wouterlood F.G., and Lanciego J.L. (Eds). Neuroanatomical Tract Tracing: Molecules, Neurons, and Systems (2006), Springer Science Business Media, New York 520-554
7. Bjaalie J.G., Leergaard T.B., Lillehaug S., Odeh F., Moene I., Kjode J.O., and Darin D. Database and tools for analysis of topographic organization and map transformations in major projection systems of the brain. Neuroscience 136 (2005) 681-696
8. Bloom F.R., and Young W.G. Database needs of neuroscience: schema and design. In: Koslow S.H., and Subramaniam S. (Eds). Databasing the Brain: From Data to Knowledge (2005), John Wiley and Sons, Inc 3-25
9. Bowden D.M., and Dubach M.F. NeuroNames 2002. Neuroinformatics 1 (2003) 43-59
10. Bug W., and Nissanov J. A guide to building image-centric databases. Neuroinformatics 1 (2003) 359-377
11. Cassarino D.S., Quezado M.M., Ghatak N.R., and Duray P.H. Lyme-associated parkinsonism: a neuropathologic case study and review of the literature. Arch. Pathol. Lab. Med. 127 (2003) 1204-1206
12. Cemal C.K., Carroll C.J., Lawrence L., Lowrie M.B., Ruddle P., Al-Mahdawi S., King R.H., Pook M.A., Huxley C., and Chamberlain S. YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit. Hum. Mol. Genet. 11 (2002) 1075-1094
13. Cepko C., Ryder E., Fekete D.M., and Bruhn S. Detection of beta-galactosidase and alkaline phosphatase activities in tissue. In: Spector D.L., Goldman R.D., and Leinwand L.A. (Eds). Cells: A Laboratory Manual, Volume 3: Subcellular Location of Genes and Their Products (1998), Cold Spring Harbor Laboratory Press, Cold Spring Harbor (Section 11)
14. Chen J., Kelz M.B., Zeng G., Sakai N., Steffen C., Shockett P.E., Picciotto M.R., Duman R.S., and Nestler E.J. Transgenic animals with inducible, targeted gene expression in brain. Mol. Pharmacol. 54 (1998) 495-503
15. Choi D.S., Wang D., Dadgar J., Chang W.S., and Messing R.O. Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. J. Neurosci. 22 (2002) 9905-9911
16. Danner H., and Pfister C. Untersuchungen zur Zytoarchitektonik des Globus pallidus der Ratte. J. Hirnforsch. 22 (1981) 47-57
17. Depino A.M., Earl C., Kaczmarczyk E., Ferrari C., Besedovsky H., del Rey A., Pitossi F.J., and Oertel W.H. Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease. Eur. J. Neurosci. 18 (2003) 2731-2747
18. Fox C.A. The intermediate cells of Lugaro in the cerebellar cortex of the monkey. J. Comp. Neurol. 112 (1959) 290-302
19. Fox C.A., Hillman D.E., Siegesmund K.A., and Dutta C.R. The primate cerebellar cortex: a Golgi and electron microscopic study. Prog. Brain Res. 25 (1967) 174-225
20. Furth P.A., St Onge L., Boger H., Gruss P., Gossen M., Kistner A., Bujard H., and Hennighausen L. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 9302-9306
21. Gerfen C.R. Basal ganglia. In: Paxinos G. (Ed). The Rat Nervous System (2005), Elsevier Academic Press, San Diego 455-508
22. Gilman S., Sima A.A., Junck L., Kluin K.J., Koeppe R.A., Lohman M.E., and Little R. Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions. Ann. Neurol. 39 (1996) 241-255
23. Gong S., Zheng C., Doughty M.L., Losos K., Didkovsky N., Schambra U.B., Nowak N.J., Joyner A., Leblanc G., Hatten M.E., and Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425 (2003) 917-925
24. Gonzalez-Hernandez T., and Rodriguez M. Compartmental organization and chemical profile of dopaminergic and GABAergic neurons in the substantia nigra of the rat. J. Comp. Neurol. 421 (2000) 107-135
25. Goodchild R.E., and Dauer W.T. Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 847-852
26. Gossen M., and Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 5547-5551
27. Gossen M., Freundlieb S., Bender G., Muller G., Hillen W., and Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 268 (1995) 1766-1769
28. Goti D., Katzen S.M., Mez J., Kurtis N., Kiluk J., Ben-Haiem L., Jenkins N.A., Copeland N.G., Kakizuka A., Sharp A.H., Ross C.A., Mouton P.R., and Colomer V. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration. J. Neurosci. 24 (2004) 10266-10279
29. Holt S., and O'Sullivan D. Studies in enzyme cytochemistry I. Principles of cytochemical staining methods. Proc. R. Soc. Lond., B Biol. Sci. 148 (1958) 465-480
30. Hoover B.R., and Marshall J.F. Further characterization of preproenkephalin mRNA-containing cells in the rodent globus pallidus. Neuroscience 111 (2002) 111-125
31. Ikeda H., Yamaguchi M., Sugai S., Aze Y., Narumiya S., and Kakizuka A. Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo. Nat. Genet. 13 (1996) 196-202
32. Iwahori N., and Mizuno N. A Golgi study on the globus pallidus of the mouse. J. Comp. Neurol. 197 (1981) 29-43
33. King J.S., and Schwyn R.C. The fine structure of neuroglial cells and pericytes in the primate red nucleus and substantia nigra. Z. Zellforsch. Mikrosk. Anat. 106 (1970) 309-321
34. Kita H., and Kita T. Number, origins, and chemical types of rat pallidostriatal projection neurons. J. Comp. Neurol. 437 (2001) 438-448
35. Kita H., and Kitai S.T. The morphology of globus pallidus projection neurons in the rat: an intracellular staining study. Brain Res. 636 (1994) 308-319
36. Lainé J., and Axelrad H. The candelabrum cell: a new interneuron in the cerebellar cortex. J. Comp. Neurol. 339 (1994) 159-173
37. Langston J.W., Forno L.S., Tetrud J., Reeves A.G., Kaplan J.A., and Karluk D. Evidence of active nerve cell generation in the substantia nigra of humans years after 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine exposure. Ann. Neurol. 46 (1999) 598-605
38. Lawson L.J., Perry V.H., Dri P., and Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience 39 (1990) 151-170
39. Lee E.F., Jacobs R.E., Dinov I., Leow A., and Toga A.W. Standard atlas space for C57BL/6J neonatal mouse brain. Anat. Embryol. 210 (2005) 245-263
40. Levesque M., Bedard A., Cossette M., and Parent A. Novel aspects of the chemical anatomy of the striatum and its efferents projections. J. Chem. Neuroanat. 26 (2003) 271-281
41. Lewandoski M. Conditional control of gene expression in the mouse. Nat. Rev., Genet. 2 (2001) 743-755
42. Liu T., Zwingman T., Li R., Pan T., Wong B.S., Petersen R.B., Gambetti P., Herrup K., and Sy M.S. Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies. Brain Res. 896 (2001) 118-129
43. MacKenzie-Graham A., Jones E.S., Shattuck D.W., Dinov I.D., Bota M., and Toga A.W. The informatics of a C57BL/6J mouse brain atlas. Neuroinformatics 1 (2003) 397-410
44. Martone M.E., Gupta A., and Ellisman M.H. E-neuroscience: challenges and triumphs in integrating distributed data from molecules to brains. Nat. Neurosci. 7 (2004) 467-472
45. Millhouse O.E. Pallidal neurons in the rat. J. Comp. Neurol. 254 (1986) 209-227
46. Mugnaini E., and Floris A. The unipolar brush cell: a neglected neuron of the mammalian cerebellar cortex. J. Comp. Neurol. 339 (1994) 174-180
47. O'Leary J.L., Petty J., Smith J.M., O'Leary M., and Inukai J. Cerebellar cortex of rat and other animals. A structural and ultrastructural study. J. Comp. Neurol. 134 (1968) 401-432
48. Orr H.T., and Zoghbi H.Y. Reversing neurodegeneration: a promise unfolds. Cell 101 (2000) 1-4
49. Paxinos G., and Franklin K.B.J. The Mouse Brain in Stereotaxic Coordinates (2001), Academic Press, San Diego
50. Probst-Cousin S., Acker T., Epplen J.T., Bergmann M., Plate K.H., Neundorfer B., and Heuss D. Spinocerebellar ataxia type 2 with glial cell cytoplasmic inclusions. J. Neurol. Neurosurg. Psychiatry 75 (2004) 503-505
51. Rosen G.D., La Porte N.T., Diechtiareff B., Pung C.J., Nissanov J., Gustafson C., Bertrand L., Gefen S., Fan Y., Tretiak O.J., Manly K.F., Park M.R., Williams A.G., Connolly M.T., Capra J.A., and Williams R.W. Informatics center for mouse genomics: the dissection of complex traits of the nervous system. Neuroinformatics 1 (2003) 327-342
52. Safar J.G., DeArmond S.J., Kociuba K., Deering C., Didorenko S., Bouzamondo-Bernstein E., Prusiner S.B., and Tremblay P. Prion clearance in bigenic mice. J. Gen. Virol. 86 (2005) 2913-2923
53. Sahin M., and Hockfield S. Molecular identification of the Lugaro cell in the cat cerebellar cortex. J. Comp. Neurol. 301 (1994) 575-584
54. Schönig K., and Bujard H. Generating conditional mouse mutants via tetracycline-controlled gene expression. In: Hofker M., and van Deursen J. (Eds). Transgenic Mouse Methods and Protocols (2003), Humana Press, Totowa 69-104
55. Sherer T.B., Betarbet R., Kim J.H., and Greenamyre J.T. Selective microglial activation in the rat rotenone model of Parkinson's disease. Neurosci. Lett. 341 (2001) 87-90
56. Sotelo C. Cerebellar neuroglia: morphological and histochemical aspects. Prog. Brain Res. 25 (1967) 226-250
57. Strömberg I., Gemma C., Vila J., and Bickford P.C. Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system. Exp. Neurol. 196 (2005) 298-307
58. Sunkin, S.M., in press. Towards the integration of spatially and temporally resolved murine gene expression databases. Trends. Genet.
59. Teismann P., and Schulz J.B. Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation. Cell Tissue Res. 318 (2004) 149-161
60. Toga A.W., Thompson P.M., Mega M.S., Narr K.L., and Blanton R.E. Probabilistic approaches for atlasing normal and disease-specific brain variability. Anat. Embryol. 204 (2001) 267-282
61. Totterdell S., Bolam J.P., and Smith A.D. Characterization of pallidonigral neurons in the rat by a combination of Golgi impregnation and retrograde transport of horseradish peroxidase: their monosynaptic input from the neostriatum. J. Neurocytol. 13 (1984) 593-616
62. Tremblay P., Meiner Z., Galou M., Heinrich C., Petromilli C., Lisse T., Cayetano J., Torchia M., Mobley W., Bujard H., DeArmond S.J., and Prusiner S.B. Doxycycline control of prion protein transgene expression modulates prion disease in mice. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 12580-12585
63. Voogd J. Cerebellum. In: Bannister L.H., Berry M.M., Collins P., Dyson M., Dussek J.E., and Ferguson M.W.J. (Eds). Gray's Anatomy (1995), Churchill Livingstone, New York 1027-1065
64. Walz R., Castro R.M., Velasco T.R., Carlotti Jr. C.G., Sakamoto A.C., Brentani R.R., and Martins V.R. Cellular prion protein: implications in seizures and epilepsy. Cell. Mol. Neurobiol. 22 (2002) 249-257
65. Wilkin G.P., and Knott C. Glia: a curtain raiser. Adv. Neurol. 80 (1999) 3-7
66. Wittenberg G.M., Sullivan M.R., and Tsien J.Z. Synaptic reentry reinforcement based network model for long-term memory consolidation. Hippocampus 12 (2002) 637-647
67. Yamamoto A., Lucas J.J., and Hen R. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 101 (2000) 57-66
68. Zu T., Duvick L.A., Kaytor M.D., Berlinger M.S., Zoghbi H.Y., Clark H.B., and Orr H.T. Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice. J. Neurosci. 24 (2004) 8853-8861