Retinoid therapy of pigmentary disorders

Dermatologic Therapy

Volumn 19, Issue 5, 2006, Pages 280-288

  Ortonne, Jean Paul ^a  

^a CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

Actinic lentigo; Depigmenting agents; Hypermelanosis; Hyperpigmentation; Melasma; Postinflammatory hypermelanosis

Indexed keywords

ADAPALENE; AZELAIC ACID; CORTICOSTEROID; DEPIGMENTING AGENT; FLUOCINOLONE ACETONIDE; GLYCOLIC ACID; HYDROCORTISONE; HYDROQUINONE; ISOTRETINOIN; LACTIC ACID; MELANIN; MEQUINOL; MONOPHENOL MONOOXYGENASE; RETINAL; RETINOIC ACID; RETINOID; RETINOL; TAZAROTENE;

ACNE; BIOAVAILABILITY; BURNING SENSATION; CELL DIFFERENTIATION; CHLOASMA; CLINICAL TRIAL; DEPIGMENTATION; DERMATITIS; DRUG EFFECT; DRUG MECHANISM; DRUG PENETRATION; DRUG POTENCY; DRUG SAFETY; DRUG TOLERABILITY; ELASTOSIS; ENZYME ACTIVITY; EPIDERMIS; ERYTHEMA; HUMAN; HYPERPIGMENTATION; HYPOPIGMENTATION; KERATINOCYTE; LENTIGO; LIGHT DAMAGE; MELANOCYTE; MELANOGENESIS; MELANOSIS; MELANOSOME; MONOTHERAPY; NONHUMAN; OCHRONOSIS; PHOTOTOXICITY; PIGMENT DISORDER; REVIEW; SEBORRHEIC KERATOSIS; SKIN ABRASION; SKIN IRRITATION; SKIN PENETRATION; STRATUM CORNEUM; ULTRAVIOLET B RADIATION;

HUMANS; PIGMENTATION DISORDERS; RETINOIDS; TREATMENT OUTCOME;

EID: 33749146991     PISSN: 13960296     EISSN: 15298019     Source Type: Journal    
DOI: 10.1111/j.1529-8019.2006.00085.x     Document Type: Review

References (56)

1. Ortonne JP, Marks R. Photodamaged skin. London: Martin Dunitz Ltd., 1999.
2. Kasraee B, Tran C, Sorg O, Saurat JH. The depigmenting effect of RALGA in C57BL/6 mice. Dermatology 2005: 210 (Suppl. 1): 30-34.
3. Ortonne JP. Pigmentary changes of the ageing skin. Br J Dermatol 1990: 122 (Suppl. 35): 21-28.
4. Breathnach AS, Nazzaro-Porro M, Passi S, Picardo M. Ultrastructure of melanocytes in chronically sun-exposed skin of elderly subjects. Pigment Cell Res 1991: 4: 71-79.
5. Zelickson AS, Mottaz JH, Weiss JS, Voorhees JJ. Topical tretinoin and photoaging: an ultrastructural study. J Cutan Aging Cosmet Dermatol 1988: 1: 41-47.
6. Stratigos AJ, Katsambas AD. The role of topical retinoids in the treatment of photoaging. Drugs 2005: 65: 1061-1072.
7. Weiss JS, Ellis CN, Headington JT, Tincoff T, Hamilton TA, Voorhees JJ. Topical tretinoin improves photoaged skin. A double-blind vehicle-controlled study. JAMA 1988: 259: 527-532.
8. Leyden JJ, Grove GL, Grove MJ, Thorne EG, Lufrano L. Treatment of photodamaged facial skin with topical tretinoin. J Am Acad Dermatol 1989: 21: 638-644.
9. Lever L, Kumar P, Marks R. Topical retinoic acid for treatment of solar damage. Br J Dermatol 1990: 122: 91-98.
10. Kang S, Voorhees JJ. Photoaging therapy with topical tretinoin: an evidence-based analysis. J Am Acad Dermatol 1998: 39: S55-S61.
11. Rafal ES, Griffiths CE, Ditre CM, et al. Topical tretinoin (retinoic acid) treatment for liver spots associated with photodamage. N Engl J Med 1992: 326: 368-374.
12. Griffiths CE, Finkel LJ, Tranfaglia MG, Hamilton TA, Voorhees JJ. An in vivo experimental model for effects of topical retinoic acid in human skin. Br J Dermatol 1993: 129: 389-394.
13. Sanchez NP, Pathak MA, Sato S, Fitzpatrick TB, Sanchez JL, Mihm MC Jr. Melasma: a clinical, light microscopic, ultrastructural, and immunofluorescence study. J Am Acad Dermatol 1981: 4: 698-710.
14. Bulengo-Ransby SM, Griffiths CE, Kimbrough-Green CK, et al. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients. N Engl J Med 1993: 328: 1438-1443.
15. Sendagorta E, Lesiewicz J, Armstrong RB. Topical isotretinoin for photodamaged skin. J Am Acad Dermatol 1992: 27: S15-S18.
16. Maddin S, Lauharanta J, Agache P, Burrows L, Zultak M, Bulger L. Isotretinoin improves the appearance of photodamaged skin: results of a 36-week, multicenter, double-blind, placebo-controlled trial. J Am Acad Dermatol 2000: 42: 56-63.
17. Kang S, Leyden JJ, Lowe NJ, et al. Tazarotene cream for the treatment of facial photodamage: a multicenter, investigator-masked, randomized, vehicle-controlled, parallel comparison of 0.01%, 0.025%, 0.05%, and 0.1% tazarotene creams with 0.05% tretinoin emollient cream applied once daily for 24 weeks. Arch Dermatol 2001: 137: 1597-1604.
18. Phillips TJ, Gottlieb AB, Leyden JJ, et al. Efficacy of 0.1% tazarotene cream for the treatment of photodamage: a 12-month multicenter, randomized trial. Arch Dermatol 2002: 138: 1486-1493.
19. Grimes P, Callender V. Tazarotene cream for postinflammatory hyperpigmentation and acne vulgaris in darker skin: a double-blind, randomized, vehicle-controlled study. Cutis 2006: 77: 45-50.
20. Kang S, Goldfarb MT, Weiss JS, et al. Assessment of adapalene gel for the treatment of actinic keratoses and lentigines: a randomized trial. J Am Acad Dermatol 2003: 49: 83-90.
21. Dogra S, Kanwar AJ, Parsad D. Adapalene in the treatment of melasma: a preliminary report. J Dermatol 2002: 29: 539-540.
22. Pathak MA, Fitzpatrick TB, Kraus EW. Usefulness of retinoic acid in the treatment of melasma. J Am Acad Dermatol 1986: 15: 894-899.
23. Taylor SC, Torok H, Jones T, et al. Efficacy and safety of a new triple-combination agent for the treatment of facial melasma. Cutis 2003: 72: 67-72.
24. Kang WH, Chun SC, Lee S. Intermittent therapy for melasma in Asian patients with combined topical agents (retinoic acid, hydroquinone and hydrocortisone). Clinical and histological studies. J Dermatol 1998: 25: 587-596.
25. Fleischer AB Jr, Schwartzel EH, Colby SI, Altman DJ. The combination of 2% 4-hydroxyanisole (Mequinol) and 0.01% tretinoin is effective in improving the appearance of solar lentigines and related hyperpigmented lesions in two double-blind multicenter clinical studies. J Am Acad Dermatol 2000: 42: 459-467.
26. Ortonne JP, Camacho F, Wainwright N, Bergfelt L, Westerhof W, Roseeuw D. Safety and efficacy of combined use of 4-hydroxyanisole (mequinol) 2%/tretinoin 0.01% solution and sunscreen in solar lentigines. Cutis 2004: 74: 261-264.
27. Burns RL, Prevost-Blank PL, Lawry MA, Lawry TB, Faria DT, Fivenson DP. Glycolic acid peels for postinflammatory hyperpigmentation in black patients. A comparative study. Dermatol Surg 1997: 23: 171-174; discussion 175.
28. Yoshimura K, Harii K, Aoyama T, Shibuya F, Iga T. A new bleaching protocol for hyperpigmented skin lesions with a high concentration of all-trans retinoic acid aqueous gel. Aesthetic Plast Surg 1999: 23: 285-291.
29. Draelos ZD. Novel approach to the treatment of hyperpigmented photodamaged skin: 4% hydroquinone/0.3% retinol versus tretinoin 0.05% emollient cream. Dermatol Surg 2005: 31: 799-804.
30. Graupe K. Combined use of 20% azelaic acid cream and 0.05% tretinoin cream in the topical treatment of melasma. J Dermatol Treat 1996: 7: 235-237.
31. Verallo-Rowell V, Sloson-Delos Reyes G. South East Asian experience with azelaic acid in melasma. Med Progress 1993: Suppl.: 26-30.
32. Boisnic S, Branchet-Gumila MC, Nocera T, Verriere F. RALGA (Diacneal) decreases melanin content in a human skin model. Dermatology 2005: 210(Suppl. 1): 35-38.
33. Uno H, Cappas A, Dong S, Kligman AM. The effect of topical tretinoin on the facial macula of the macaque. J Invest Dermatol 1991: 96: 632.
34. Zheng P, Kligman AM. Topical tretinoin stimulates melanogenesis in the Yucatan micropig. J Invest Dermatol 1991: 96: 576.
35. Ho KK, Halliday GM, Barnetson RS. Topical retinoic acid augments ultraviolet light-induced melanogenesis. Melanoma Res 1992: 2: 41-45.
36. Talwar HS, Griffiths CE, Fisher GJ, et al. Differential regulation of tyrosinase activity in skin of white and black individuals in vivo by topical retinoic acid. J Invest Dermatol 1993: 100: 800-805.
37. Romero C, Aberdam E, Larnier C, Ortonne JP. Retinoic acid as modulator of UVB-induced melanocyte differentiation. Involvement of the melanogenic enzymes expression. J Cell Sci 1994: 107: 1095-1103.
38. Ortonne JP. Retinoic acid and pigment cells: a review of in vitro and in vivo studies. Br J Dermatol 1992: 127 (Suppl. 41): 43-47.
39. Rosdahl I, Andersson E, Kagedal B, Torma H. Vitamin A metabolism and mRNA expression of retinoid-binding protein and receptor genes in human epidermal melanocytes and melanoma cells. Melanoma Res 1997: 7: 267-274.
40. Spanjaard RA, Ikeda M, Lee PJ, Charpentier B, Chin WW, Eberlein TJ. Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RAR-gamma in induction of differentiation and apoptosis of S91 melanoma cells. J Biol Chem 1997: 272: 18990-18999.
41. Lotan R, Lotan D. Stimulation of melanogenesis in a human melanoma cell line by retinoids. Cancer Res 1980: 40: 3345-3350.
42. Lotan R, Lotan D. Enhancement of melanotic expression in cultured mouse melanoma cells by retinoids. J Cell Physiol 1981: 106: 179-189.
43. Hoal E, Wilson EL, Dowdle EB. Variable effects of retinoids on two pigmenting human melanoma cell lines. Cancer Res 1982: 42: 5191-5195.
44. Hosoi J, Abe E, Suda T, Kuroki T. Regulation of melanin synthesis of B16 mouse melanoma cells by 1 alpha, 25-dihydroxyvitamin D3 and retinoic acid. Cancer Res 1985: 45: 1474-1478.
45. Edward M, Gold JA, MacKie RM. Different susceptibilities of melanoma cells to retinoic acid-induced changes in melanotic expression. Biochem Biophys Res Commun 1988: 155: 773-778.
46. Chakraborty AK, Orlow SJ, Pawelek JM. Stimulation of the receptor for melanocyte-stimulating hormone by retinoic acid. FEBS Lett 1990: 276: 205-208.
47. Orlow SJ, Chakraborty AK, Pawelek JM. Retinoic acid is a potent inhibitor of inducible pigmentation in murine and hamster melanoma cell lines. J Invest Dermatol 1990: 94: 461-464.
48. Fligiel SE, Inman DR, Talwar HS, Fisher GJ, Voorhees JJ, Varani J. Modulation of growth in normal and malignant melanocytic cells by all-trans retinoic acid. J Cutan Pathol 1992: 19: 27-33.
49. Fisher GJ, Esmann J, Griffiths CE. Cellular, immunologic and biochemical characterization of topical retinoic acid-treated human skin. J Invest Dermatol 1991: 96.
50. Niles RM, Loewy BP. Induction of protein kinase C in mouse melanoma cells by retinoic acid. Cancer Res 1989: 49: 4483-4487.
51. Gruber JR, Ohno S, Niles RM. Increased expression of protein kinase C alpha plays a key role in retinoic acid-induced melanoma differentiation. J Biol Chem 1992: 267: 13356-13360.
52. Weiss JS, Ellis CN, Headington JT, Voorhees JJ. Topical tretinoin in the treatment of aging skin. J Am Acad Dermatol 1988: 19: 169-175.
53. Weinstein GD, Nigra TP, Pochi PE, et al. Topical tretinoin for treatment of photodamaged skin. A multicenter study. Arch Dermatol 1991: 127: 659-665.
54. Kasraee B, Handjani F, Aslani FS. Enhancement of the depigmenting effect of hydroquinone and 4-hydroxyanisole by all-trans-retinoic acid (tretinoin): the impairment of glutathione-dependent cytoprotection? Dermatology 2003: 206: 289-291.
55. Kligman AM, Willis I. A new formula for depigmenting human skin. Arch Dermatol 1975: 111: 40-48.
56. Tadaki T, Watanabe M, Kumasaka K, et al. The effect of topical tretinoin on the photodamaged skin of the Japanese. Tohoku J Exp Med 1993: 169: 131-139.