The depigmenting effect of RALGA in C57BL6 mice

Dermatology

Volumn 210, Issue SUPPL. 1, 2005, Pages 30-34

  Kasraee, B ^a,b   Tran, C ^a   Sorg, O ^a   Saurat, J H ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Depigmentation after acne; Diacn al ; Melanin; Melanocytes; Melasma; Retinaldehyde; Retinoic acid; Tyrosinase

Indexed keywords

ANTI ACNE AGENT; DIACNEAL; MELANIN; RETINALDEHYDE PLUS GLYCOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DEPIGMENTATION; DRUG EFFECT; HYPERPIGMENTATION; MELANOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYNTHESIS; TAIL;

ACNE VULGARIS; ANIMALS; DERMATOLOGIC AGENTS; DRUG COMBINATIONS; GLYCOLATES; HYPERPIGMENTATION; KERATOLYTIC AGENTS; MELANINS; MELANOCYTES; MICE; MICE, INBRED C57BL; RETINALDEHYDE; SKIN; SKIN PIGMENTATION; TAIL; TIME FACTORS;

EID: 16344393705     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000081499     Document Type: Conference Paper

References (18)

1. Kligman AM, Willis I: A new formula for depigmenting human skin. Arch Dermatol 1975;111:40-48.
2. Griffiths CE, Finkel LJ, Ditre CM, Hamilton TA, Ellis CN, Voorhees JJ: Topical tretinoin (retinoic acid) improves melasma: A vehicle-controlled, clinical trial. Br J Dermatol 1993;129:415-421.
3. Rafal ES, Griffiths CE, Ditre CM, Finkel LJ, Hamilton TA, Ellis CN, Voorhees JJ: Topical tretinoin (retinoic acid) treatment for liver spots associated with photodamage. N Engl J Med 1992;326:368-374.
4. Fullerton A, Serup J: Characterization of irritant patch test reactions to topical D vitamins and all-trans-retinoic acid in comparison with sodium lauryl sulphate: Evaluation by clinical scoring and multiparametric non-invasive measuring techniques. Br J Dermatol 1997;137:234-240.
5. Fluhr JW, Vienne MP, Lauze C, Dupuy P, Gehring W, Gloor M: Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions. Dermatology 1999;199(suppl 1):57-60.
6. Nair X, Parab P, Suhr L, Tramposch KM: Combination of 4-hydroxyanisole and all-trans retinoic acid produces synergistic skin depigmentation in swine. J Invest Dermatol 1993;101:145-149.
7. Didierjean L, Tran C, Sorg O, Saurat JH: Biological activities of topical natural retinaldehyde. Dermatology 1999;199(suppl):19-24.
8. Saurat JH, Didierjean L, Masgrau E, Piletta PA, Jaconi S, Chatellard-Gruaz D, Gumowski D, Masouyé I, Salomon I, Siegenthaler G: Topical retinaldehyde on human skin: Biological effects and tolerance. J Invest Dermatol 1994;103:770-774.
9. Bessou S, Pain C, Taïeb A: Use of human skin reconstructs in the study of pigment modifiers. Arch Dermatol 1997;133:331-336.
10. Orlow SJ, Chakraborty AK, Boissy RE, Pawelek JM: Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers. Exp Cell Res 1990;191:209-218.
11. Ito Y, Jimbow K, Ito S: Depigmentation of black guinea pig skin by topical application of cysteaminylphenol, cysteinylphenol, and related compounds. J Invest Dermatol 1987;88:77-82.
12. Frenk E: Experimental depigmentation of guinea pig skin by selective toxic action of the monoethyl ether of hydroquinone on melanocytes. Arch Klin Exp Dermatol 1969;235:16-24.
13. Romero C, Aberdam E, Larnier C, Ortonne JP: Retinoic acid as modulator of UVB-induced melanocyte differentiation: Involvement of the melanogenic enzymes expression. J Cell Sci 1994;107:1095-1103.
14. Kasraee B, Handjani F, Aslani FS: Enhancement of the depigmenting effect of hydroquinone and 4-hydroxyanisole by all-trans-retinoic acid (tretinoin): The impairment of glutathione-dependent cytoprotection? Dermatology 2003;206:289-291.
15. Tung RC, Bergfeld WF, Vidimos AT, Remzi BK: α-Hydroxy-acid-based cosmetic procedures: Guidelines for patient management. Am J Clin Dermatol 2000;1:81-88.
16. Bordat P, Chesnoy S: Mixing glycolic acid with retinaldehyde: RALGA, a technical achievement. Dermatology 2005;210(suppl 1):2-5.
17. Tran C, Kasraee B, Grand D, Carraux P, Didierjean L, Sorg O, Saurat .J-H: Pharmacology of RALGA, a mixture of retinaldehyde and glycolic acid. Dermatology 2005;210(suppl 1):6-13.
18. Boisnic S, Branchet-Gumila M-C, Nocera T, Verrière F: RALGA decreases melanin content in a human skin model. Dermatology 2005;210(suppl 1):35-38.