Pavlovian conditioning of nausea and vomiting

Autonomic Neuroscience: Basic and Clinical

Volumn 129, Issue 1-2, 2006, Pages 50-57

  Stockhorst, Ursula ^a   Steingrueber, Hans Joachim ^a   Enck, Paul ^b   Klosterhalfen, Sibylle ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Chemotherapy; Cortisol; Gender; Motion sickness; Nausea; Pavlovian conditioning; Tumor necrosis factor ; Vomiting

Indexed keywords

ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; HYDROCORTISONE; TUMOR NECROSIS FACTOR ALPHA;

ANTICIPATORY NAUSEA AND VOMITING; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CHEMOTHERAPY INDUCED EMESIS; CONDITIONING; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DRUG EXPOSURE; DRUG INFUSION; ENDOCRINE SYSTEM; EXPERIMENTAL STUDY; FOOD AVERSION; HUMAN; HYDROCORTISONE RELEASE; IMMUNE RESPONSE; IMMUNOMODULATION; MOTION SICKNESS; NAUSEA; NAUSEA AND VOMITING; NONHUMAN; PRIORITY JOURNAL; ROTATION; SEX DIFFERENCE; TASTE AVERSION; VALIDATION STUDY; VALIDITY; VOMITING;

ANIMALS; ANTINEOPLASTIC AGENTS; CONDITIONING, CLASSICAL; FEMALE; HUMANS; MALE; MOTION SICKNESS; NAUSEA; NEOPLASMS; SEX FACTORS; VOMITING, ANTICIPATORY;

EID: 33749144707     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2006.07.012     Document Type: Article

References (33)

1. Aapro M.S., Molassiotis A., and Olver I. Anticipatory nausea and vomiting. Support. Care Cancer 13 (2005) 117-121
2. Andrykowski M.A., and Otis M.L. Development of learned food aversions in humans: investigation in a "natural laboratory" of cancer chemotherapy. Appetite 14 (1990) 145-158
3. Basu M., Sawhney R.C., Kumar S., Pal K., Prasad R., and Selvamurthy W. Glucocorticoids as prophylaxis against acute motion sickness. Clin. Endocrinol. 57 (2002) 761-767
4. Bernstein I.L. Neural mediation of food aversions and anorexia induced by tumor necrosis factor and tumors. Neurosci. Biobehav. Rev. 20 (1996) 177-181
5. Cheung B., and Hofer K. Lack of gender difference in motion sickness induced by vestibular Coriolis cross-coupling. J. Vestib. Res. 12 (2002-2003) 191-200
6. Cleeland C.S., Bennett G.J., Dantzer R., Dougherty P.M., Dunn A.J., Meyers C.A., Miller A.H., Payne R., Reuben J.M., Wang X.S., and Lee B.N. Are the symptoms of cancer and cancer treatment due to a shared biologic mechanism? A cytokine-immunological model of cancer symptoms. Cancer 97 (2003) 2919-2925
7. Dantzer R. Cytokine-induced sickness behavior: mechanisms and implications. Ann. N. Y. Acad. Sci. 933 (2001) 222-234
8. Dantzer R. Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur. J. Pharmacol. 500 (2004) 399-411
9. Donegan N.H. Priming-produced facilitation or diminution of responding to a Pavlovian unconditioned stimulus. J. Exp. Psychol. Anim. Behav. Process 7 (1981) 295-312
10. Fessler D.M.T., and Arguello A.P. The relationship between susceptibility to nausea and vomiting and the possession of conditioned food aversions. Appetite 43 (2004) 331-334
11. Flaherty C.F. Animal Learning and Cognition (1985), Alfred A. Knopf Inc., New York
12. Fredrikson M., Hursti T., Fürst C.J., Steineck G., Börjeson S., Wikblom M., and Peterson C. Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion. Br. J. Cancer 65 (1992) 779-780
13. Jokerst M.D., Gatto M., Fazio R., Gianaros P.J., Stern R.M., and Koch K.L. Effects of gender of subjects and experimenter on susceptibility to motion sickness. Aviat. Space Environ. Med. 70 (1999) 962-965
14. Jordan K., Kasper C., and Schmoll H.-J. Chemotherapy-induced nausea and vomiting: current and new standards in the antiemetic prophylaxis and treatment. Eur. J. Cancer 41 (2005) 199-205
15. Klosterhalfen S., Rüttgers A., Krumrey E., Otto B., Stockhorst U., Riepl R.L., Probst T., and Enck P. Pavlovian conditioning of taste aversion using a motion sickness paradigm. Psychosom. Med. 62 (2000) 671-677
16. Klosterhalfen S., Kellermann S., Stockhorst U., Wolf J., Kirschbaum C., Hall G., and Enck P. Latent inhibition of rotation-chair induced nausea in healthy male and female volunteers. Psychosom. Med. 67 (2005) 335-340
17. Lee B.N., Dantzer R., Langley K.E., Bennett G.J., Dougherty P.M., Dunn A.J., Meyers C.A., Miller A.H., Payne R., Reuben J.M., Wang X.S., and Cleeland C.S. A cytokine-based neuroimmunological mechanism of cancer-related symptoms. Neuroimmunomodulation 11 (2004) 279-292
18. Lubow R.E., and Moore A.U. Latent inhibition: the effect of non reinforced pre-exposure to the conditional stimulus. J. Comp. Physiol. Psychol. 52 (1959) 415-419
19. Mazur J.E. Learning and Behavior (2002), Prentice Hall, New Jersey
20. Morrow G.R., Hickok J.T., and Rosenthal S.N. Progress in reducing nausea and emesis. Comparisons of ondansetron (Zofran), granisetron (Kytril), and tropisetron (Navoban). Cancer 76 (1995) 343-357
21. 3 antiemetics. Support. Care Cancer 6 (1998) 244-247
22. Park A.H., and Hu S. Gender differences in motion sickness history and susceptibility to optokinetic rotation-induced motion sickness. Aviat. Space Environ. Med. 70 (1999) 1077-1080
23. Pavlov I.P. Conditioned Reflexes (1927/1960), New York, Dover
24. Plata-Salamán C.R. Brain mechanisms in cytokine-induced anorexia. Psychoneuroendocrinology 24 (1999) 25-41
25. Ramsay D.S., and Woods S.C. Biological consequences of drug administration: implications for acute and chronic tolerance. Psychol. Rev. 104 (1997) 170-193
26. Rodriguez M., Lopez M., Symonds M., and Hall G. Lithium-induced context aversion in rats as a model of anticipatory nausea in humans. Physiol. Behav. 71 (2000) 571-579
27. Rohleder N., Otto B., Wolf J.M., Klose J., Kirschbaum C., Enck P., and Klosterhalfen S. Sex-specific adaptation of endocrine and inflammatory responses to repeated nauseogenic body rotation. Psychoneuroendocrinology 31 (2006) 226-236
28. Stockhorst U., Spennes-Saleh S., Körholz D., Göbel U., Schneider M.E., Steingrüber H.J., and Klosterhalfen S. Anticipatory nausea in cancer patients receiving chemotherapy: classical conditioning etiology and therapeutical implications. Integr. Physiol. Behav. Sci. 28 (1993) 177-181
29. Stockhorst U., Wiener J.A., Klosterhalfen S., Klosterhalfen W., Aul C., and Steingrüber H.J. Effects of overshadowing on conditioned nausea in cancer patients: an experimental study. Physiol. Behav. 64 (1998) 743-753
30. Stockhorst U., Spennes-Saleh S., Körholz D., Göbel U., Schneider M.E., Steingrüber H.J., and Klosterhalfen S. Anticipatory symptoms and anticipatory immune responses in pediatric cancer patients receiving chemotherapy: features of a classically conditioned response?. Brain Behav. Immun. 14 (2000) 198-218
31. Symonds M., and Hall G. Contextual conditioning with an illness US is attenuated by the antiemetic ondansetron. Psychobiology 28 (2000) 360-366
32. Symonds M., and Hall G. Postinjection suppression of drinking is modified by the presence of conditioned contextual cues: implications for both anticipatory and post-treatment nausea in humans. Anim. Learn. Behav. 30 (2002) 355-362
33. Yates B.J., Miller A.D., and Lucot J.B. Physiological basis and pharmacology of motion sickness: an update. Brain Res. Bull. 47 (1998) 395-406