Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice

Journal of Hepatology

Volumn 45, Issue 5, 2006, Pages 725-733

  Souza de Oliveira, Claudia Pinto Marques ^a   Stefano, José Tadeu ^a   de Lima, Vicência Mara Rodrigues ^a   de Sá, Sandra Valéria ^a   Simplicio, Fernanda Ibanez ^b   de Mello, Evandro Sobrosa ^a   Corrêa Giannella, Maria Lúcia ^a   Ferreira Alves, Venâncio Avancini ^a   Martins Laurindo, Francisco Rafael ^a   de Oliveira, Marcelo Ganzarolli ^b   Giannella Neto, Daniel ^a   Carrilho, Flair José ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Hepatic gene expression; Nitric Oxide; Non alcoholic steatohepatitis; S Nitroso N acetylcysteine

Indexed keywords

CHOLINE; LIPID PEROXIDE; METHIONINE; N ACETYL S NITROSOCYSTEINE; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CYTOTOXICITY; DIET; DOWN REGULATION; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; FEEDING; FOOD INTAKE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; LIVER; MALE; MICROARRAY ANALYSIS; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; CHOLINE DEFICIENCY; DOWN-REGULATION; FATTY ACIDS; FATTY LIVER; GENE EXPRESSION PROFILING; LIPID PEROXIDATION; MALE; MICE; MODELS, ANIMAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 33749061681     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.05.017     Document Type: Article

References (29)

1. McCullough A.J. Update on nonalcoholic fatty liver disease. J Clin Gastroenterol 34 (2002) 255-262
2. Chitturi S., and Farrell G. Ethiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis 21 (2001) 27-41
3. Yang S.Q., Zhu H., Li Y., Gabrielson K., Trush M.A., and Diehl A.M. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 378 (2000) 259-268
4. Curzio M., Esterbauer H., and Dianzani M.U. Chemotactic activity of hydroxyalkenals on rat neutrophils. Int J Tissue React 7 (1985) 137-142
5. Lee K.S., Buck M., Houglum K., and Chojkier M. Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 96 (1995) 2461-2468
6. Pessayre D., Berson A., Fromenty B., and Mansouri A. Mitochondria in steatohepatitis. Semin Liver Dis 21 (2001) 57-69
7. Brady L.J., Brady P.S., Romsos D.R., and Hoppel C.L. Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice. Biochem J 231 (1985) 439-444
8. Sanyal A.J., Campbell-Sargent C., Mirshahi F., Rizzo W.B., Contos M.J., Sterling R.K., et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 120 (2001) 1183-1192
9. Haque M., Mirshahi F., Campbell-Sargent C., Sterling R.K., Luketic V.A., Shiffman V.A., et al. Nonalcoholic steatohepatitis (NASH) is associated with hepatocyte mitochondrial DNA depletion [Abstract]. Hepatology 36 (2002) 403A
10. Pérez-Carreras M., Del Hoyo P., Martin M.A., Rubio J.C., Martin A., Castellano G., et al. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. Hepatology 38 (2003) 999-1007
11. Hubbo H., Darley-Usmar V., and Freeman B.A. Nitric oxide regulation of tissue free radical injury. Chem Res Toxicol 9 (1996) 809-820
12. Hogg N., and Kalyanaraman B. Nitric oxide and lipid peroxidation. Biochem Biophys Acta 1411 (1999) 378-384
13. Violi F., Marino R., Milite M.T., and Loffredo L. Nitric oxide and its role in lipid peroxidation. Diabetes Metab Res Rev 15 (1999) 283-288
14. Giustarini D., Milzani A., Colombo R., Dalle-Donne I., and Rossi R. Nitric oxide and S-nitrosothiols in human blood. Clin Chim Acta 330 (2003) 85-98
15. Oliveira C.P.M.S., Simplicio F.I., Lima V.M.R., Yuahasi K., Lopasso F.P., Alves V.A.F., et al. Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats. World J Gastroenterol 12 (2006) 1905-1911
16. Santos K.F.R., Shishido S.M., Oliveira M.G., and Krieger M.H. Characterization of the hypotensive effect of S-nitroso-N-acetylcysteine in normotensive and hypertensive conscious rats. Nitric Oxide 7 (2002) 57-66
17. Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25 (2000) 25-29
18. Doniger S.W., Salomonis N., Dahlquist K.D., Vranizan K., Lawlor S.C., and Conklin B. MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol 4 (2003) R7
19. Reiner A., Yekutieli D., and Benjamini Y. Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics 19 (2003) 368-375
20. O'Brien R.M., and Granner D.K. Regulation of gene expression by insulin. Physiol Rev 76 (1996) 1109-1161
21. Koteish A., and Diehl A.M. Animal models of steatosis. Semin Liver Dis 21 (2001) 89-104
22. Hensley K., Kotake Y., Sang H., Pye Q.N., Wallis G.L., Kolker L.M., et al. Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis 21 (2000) 983-989
23. Rushmore T.H., Lim Y.P., Farber E., and Ghoshal A.K. Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine. Cancer Lett 24 (1984) 251-255
24. Ghoshal A.K., Monserrat A.J., Porta E.A., and Hartroft W.S. Role of lipoperoxidation in early choline deficiency. Exp Mol Pathol 12 (1970) 31-35
25. Jefferies H., Coster J., Khalil A., Bot J., McCauley R.D., and Hall J.C. Glutathione. ANZ J Surg 73 (2003) 517-522
26. Tran K., Thorne-Tjomsland G., DeLong C.J., Cui Z., Shan J., Burton L., et al. Intracellular assembly of very low density lipoproteins containing apolipoprotein B100 in rat hepatoma McA-RH777 cells. J Biol Chem 277 (2002) 31187-31200
27. Bartels E.D., Lauritsen M., and Nielsen L.B. Hepatic expression of microsomal triglyceride transfer protein and in vivo secretion of triglyceride-rich lipoproteins are increased in obese diabetic mice. Diabetes 51 (2002) 1233-1239
28. Barthel A., and Schmoll D. Novel concepts in insulin regulation of hepatic gluconeogenesis. Am J Physiol Endocrinol Metab 285 (2003) E685-E692
29. Carvalho-Filho M.A., Ueno M., Hirabara S.M., Seabra A.B., Carvalheira J.B.C., Oliveira M.G., et al. S-nitrosylation of insulin receptor, insulin receptor substrate-1 and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes 54 (2005) 959-967