Distribution of Fos immunoreactivity in the lamina terminalis and hypothalamus induced by centrally administered relaxin in conscious rats

Journal of Neuroendocrinology

Volumn 9, Issue 6, 1997, Pages 431-437

  McKinley, M J ^a   Burns, P ^a   Colvill, L M ^a   Oldfield, B J ^a   Wade, J D ^a   Weisinger, R S ^a   Tregear, G W ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Fos; Lamina terminalis; Oxytocin; Relaxin; Subfornical organ; Vasopressin

Indexed keywords

RELAXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CEREBROSPINAL FLUID; FOREBRAIN; HYPOTHALAMUS; IMMUNOREACTIVITY; MALE; NONHUMAN; PREOPTIC NUCLEUS; PRIORITY JOURNAL; RAT; SUBFORNICAL ORGAN; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS;

EID: 0030997318     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.1997.00600.x     Document Type: Article

References (29)

1. Geddes BJ, Summerlee AJS. The emerging concept of relaxin as a centrally acting peptide hormone with hemodynamic actions. J Neuroendocrinol 1995; 7: 411-417.
2. Summerlee AJS, O'Byrne KT, Paisley AC, Breeze MF, Porter DG. Relaxin affects the central control of oxytocin release. Nature 1984; 309: 372-374.
3. Jones SA, Summerlee AJS. Relaxin acts centrally to inhibit oxytocin release during parturition: an effect that is reversed by naloxone. J Endocrinol 1986; 11: 99-102.
4. O'Byrne KT, Eltringham L, Summerlee AJS. Central inhibitory effects of relaxin on the milk ejection reflex of the rat depends upon the site of injection into the cerebroventricular system. Brain Res 1987; 405: 80-83.
5. Mumford AD, Parry LJ, Summerlee AJS. Lesion of the subfornical organ affects the haemotensive response to centrally administered relaxin in anaesthetised rats. J Endocrinol 1989; 123: 747-755.
6. Summerlee JS, Robertson GF. Central administration of porcine relaxin stimulates drinking behaviour in rats: an effect mediated by central angiotensin II. Endocrine 1995; 3: 377-381.
7. Thornton SN, Fitzsimons JT. The effects of centrally administered porcine relaxin on drinking behaviour in male and female rats. J Neuroendocrinol 1995; 7: 165-170.
8. Summerlee AJS, O'Byrne KT, Jones SA, Eltringham L. The subfornical organ and relaxin induced inhibition of reflex milk ejection in lactating rats. J Endocrinol 1987; 115: 347-353.
9. Sherwood OD. Relaxin. In: Knobil E, Neill JD. eds. The Physiology of Reproduction, New York: Raven Press 1994: 2nd edn, 861-1009.
10. Gunnerson J, Crawford RJ, Tregear GW. Expression of the relaxin gene in rat tissues. Mol. Cell. Endocrinol 1995; 110: 55-64.
11. Osheroff PL. Relaxin receptors in the rat uterus, brain, and heart. In: MacLennan AH, Tregear GW, Bryant-Greenwood G. eds. Progress in Relaxin Research, 159-176. Singapore: World Scientific Publishing Co, 1994: 159-176.
12. Osheroff PL, Phillips HS. Autoradiographic localization of relaxin binding sites in rat brain. Proc Nat Acad Sci USA 1991; 88: 6413-6417.
13. McKinley MJ, Pennington GL, Oldfield BJ. The anteroventral wall of the third ventricle and dorsal lamina terminalis: headquarters for control of body fluid homeostasis? Clin Exp Pharmacol Physiol 1996; 23:271-281.
14. McKinley MJ, McAllen RM, Mendelsohn FAO, Allen AM, Chai SY, Oldfield BJ. Circumventricular organs: neuroendocrine interfaces between the brain and the hemal milieu. Front Neuroendocrinol 1990; 11: 91-127.
15. Morgan JI, Cohen DR, Hempstead JL, Curran T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science 1987; 237: 192-237.
16. Sagar SM, Sharp FR, Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 1988; 40: 1328-1331.
17. McKinley MJ, Badoer E, Oldfield BJ. Intravenous angiotensin II induces Fos-immunoreactivity in Circumventricular organs of the lamina terminalis. Brain Res 1992; 594: 295-300.
18. McKinley MJ, Badoer E, Vivas L, Oldfield BJ. Comparison of c-fos expression in the lamina terminalis of conscious rats after intravenous or intracerebroventricular angiotensin. Brain Res Bull 1995; 37: 131-137.
19. Oldfield BJ, Badoer E, Hards DK, McKinley MJ. Fos production in retrogradely labelled neurons of the lamina terminalis following intravenous infusion of either hypertonic saline or angiotensin II. Neuroscience 1994; 60: 255-262.
20. Miselis RR, Weiss ML, Schapiro RE. Modulation of the visceral neuraxis. In: Gross PM, ed. Circumventricular Organs and Body Fluids, Boca Raton: CRC Press, 1987: vol. III. 143-162.
21. Oldfield BJ, Hards DK, McKinley MJ. Projections from the subfornical organ to the supraoptic nucleus in the rat: ultrastructural identification of an interposed synapse in the median preoptic nucleus using a combination of neuronal tracers. Brain Res 1991; 558: 13-19.
22. Saper CB, Lewisohn D. Afferent neural connections of the median preoptic nucleus in the rat: anatomical evidence for a cardiovascular integrative mechanism in the anteroventral third ventricular (AV3 V) region. Brain Res 1983; 230: 21-31.
23. McKinley MJ, Denton MJ, Weisinger RS. Sensors for antidiuresis and thirst - osmoreceptors or CSF sodium detectors. Brain Res 1978; 141: 89-103.
24. Mangiapane ML, Thrasher TN, Keil LC, Simpson JB, Ganong WF. Deficits in drinking and vasopressin secretion after lesions of the nucleus medianus. Neuroendocrinology 1993; 37: 73-77.
25. Weisinger RS, Burns P, Eddie LW, Wintour EM. Relaxin alters the plasma osmolality-arginine vasopressin relationship in the rat. J Endocrinol 1993; 137: 505-510.
26. Way S, Leng G. Relaxin increases the firing rate of supraoptic neurons and increases oxytocin secretion in the rat. J Endocrinol 1992; 132: 149-158.
27. Tregear GT, Wade JD. Chemistry, synthesis and processing of relaxin, In: MacLennan AH, Tregear GW, Bryant-Greenwood G, eds. Progress in Relaxin Research, Singapore: World Scientific Publishing Co, 1994: 31-44.
28. Kakouris H, Eddie LW, Summers RJ. Cardiac effects of relaxin in rats. Lancet 1992; 339: 1076-1078.
29. Summers RJ, Yeow Tan Y, Kakouris H, Eddie LW. Cardiac actions of relaxin, In: MacLennan AH, Tregear GW, Bryant-Greenwood G. eds. Progress in Relaxin Research, Singapore: World Scientific Publishing Co, 1994: 487-498.