In vitro studies on the signal transduction of thyroidal uptake of 18F-FDG and131I-iodide

Journal of Nuclear Medicine

Volumn 47, Issue 8, 2006, Pages 1382-1388

  Bläser, Daniel ^a   Maschauer, Simone ^a   Kuwert, Torsten ^a   Prante, Olaf ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

18F FDG; FRTL 5 cells; PET; Thyroid; Thyroid stimulating hormone

Indexed keywords

BUCLADESINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FLUORODEOXYGLUCOSE F 18; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; IODINE 131; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RADIOACTIVE IODINE; THYROTROPIN; TRACER; WORTMANNIN; GLUCOSE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CELL MEMBRANE; CONCENTRATION RESPONSE; DRUG UPTAKE; IODINE 131 UPTAKE TEST; METASTASIS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; THYROID CANCER; THYROID CELL; WESTERN BLOTTING; ANIMAL; CELL DIFFERENTIATION; IN VITRO STUDY; METABOLISM; METHODOLOGY; POSITRON EMISSION TOMOGRAPHY; SCINTISCANNING; THYROID TUMOR; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FLUORODEOXYGLUCOSE F18; GLUCOSE; IODINE RADIOISOTOPES; NEOPLASM METASTASIS; POSITRON-EMISSION TOMOGRAPHY; RATS; SIGNAL TRANSDUCTION; THYROID NEOPLASMS; THYROTROPIN;

EID: 33749047452     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Reske SN, Kotzerke J. FDG-PET for clinical use: results of the 3rd German Interdisciplinary Consensus Conference. Eur J Nucl Med. 2001;28:1707-1723.
2. 18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor. J Nucl Med. 2005;46:675-682.
3. Haberkorn U, Altmann A, Kamencic H, et al. Glucose transport and apoptosis after gene therapy with HSV thymidine kinase. Eur J Nucl Med. 2001;28:1690-1696.
4. 18F]FDG uptake and PCNA, Glut-1, and hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasia. 2005;7:369-379.
5. 18F-FDG uptake in human endothelial cells through increased hexokinase activity and GLUT1 expression. J Nucl Med. 2005;46:365-370.
6. 18F-FDG PET results in lung cancer staging. J Nucl Med. 2004;45:999-1003.
7. 18F-FDG uptake in activated monocytes occurs during the priming process and involves tyrosine kinases and protein kinase C. J Nucl Med. 2004;45:124-128.
8. 18F]fluorodeoxyglucose in human monocyte-macrophages in vitro. Eur J Nucl Med Mol Imaging. 2003;30:267-273.
9. 18F-FDG uptake in human endothelial cells in vitro. J Nucl Med. 2004;45:455-460.
10. 18F]fluorodeoxyglucose in human thyroid cells in vitro. Eur J Nucl Med Mol Imaging. 2004;31:507-512.
11. Sisson JC, Ackermann RJ, Meyer MA, Wahl RL. Uptake of 18-fluoro-2-deoxy-D-glucose by thyroid cancer: implications for diagnosis and therapy. J Clin Endocrinol Metab. 1993;77:1090-1094.
12. Moog F, Linke R, Manthey N, et al. Influence of thyroid-stimulating hormone levels on uptake of FDG in recurrent and metastatic differentiated thyroid carcinoma. J Nucl Med. 2000;41:1989-1995.
13. 18F]fluorodeoxyglucose uptake by differentiated thyroid carcinoma. Eur J Nucl Med Mol Imaging. 2002;29:641-647.
14. 18fluorodeoxyglucose-positron emission tomography in patients with metastatic differentiated thyroid carcinoma during thyrotropin stimulation. Thyroid. 2002;12:381-387.
15. Grünwald F, Kalicke T, Feine U, et al. Fluorine-18 fluorodeoxyglucose positron emission tomography in thyroid cancer: results of a multicentre study. Eur J Nucl Med. 1999;26:1547-1552.
16. 131I whole body scans and elevated serum thyroglobulin levels. J Clin Endocrinol Metab. 1999;84:2291-2302.
17. Ambesi-Impiombato FS, Picone R, Tramontano D. Influence of hormones and serum on growth and differentiation of the thyroid cell strain FRTL. In: Sato GH, Pardee AB, Sirbaku DA, eds. Growth of Cells in Hormonally Defined Media. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1982:483-492.
18. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
19. Samih N, Hovsepian S, Aouani A, Lombardo D, Fayet G. Glut-1 translocation in FRTL-5 thyroid cells: role of phosphatidylinositol 3-kinase and N-glycosylation. Endocrinology. 2000;141:4146-4155.
20. Brandi ML, Rotella CM, Mavilia C, Franceschelli F, Tanini A, Toccafondi R. Insulin stimulates cell growth of a new strain of differentiated rat thyroid cells. Mol Cell Endocrinol. 1987;54:91-103.
21. Kimura T, Dumont JE, Fusco A, Golstein J. Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells. Eur J Endocrinol. 1999;140:94-103.
22. Hosaka Y, Tawata M, Kurihara A, Ohtaka M, Endo T, Onaya T. The regulation of two distinct glucose transporter (GLUT1 and GLUT4) gene expressions in cultured rat thyroid cells by thyrotropin. Endocrinology. 1992;131:159-165.
23. Russo D, Damante G, Foti D, Costante G, Filetti S. Different molecular mechanisms are involved in the multihormonal control of glucose transport in FRTL5 rat thyroid cells. J Endocrinol Invest. 1994;17:323-327.
24. Spitzweg C, Joba W, Morris JC, Heufelder AE. Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells. Thyroid. 1999;9:821-830.
25. Pang XP, Park M, Hershman JM. Transforming growth factor-beta blocks protein kinase-A-mediated iodide transport and protein kinase-C-mediated DNA synthesis in FRTL-5 rat thyroid cells. Endocrinology. 1992;131:45-50.
26. Santisteban P, Kohn LD, Di Lauro R. Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells. J Biol Chem. 1987;262:4048-4052.
27. Kimura T, Van Keymeulen A, Golstein J, Fusco A, Dumont JE, Roger PP. Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models. Endocr Rev. 2001;22:631-656.
28. Davies TF, Yang C, Platzer M. Cloning the Fisher rat thyroid cell line (FRTL-5): variability in clonal growth and 3′,5′-cyclic adenosine monophosphate response to thyrotropin. Endocrinology. 1987;121:78-83.
29. Filetti S, Damante G, Foti D. Thyrotropin stimulates glucose transport in cultured rat thyroid cells. Endocrinology. 1987;120:2576-2581.
30. Nedachi T, Akahori M, Ariga M, et al. Tyrosine kinase and phosphatidylinositol 3-kinase activation are required for cyclic adenosine 3′,5′-monophosphate-dependent potentiation of deoxyribonucleic acid synthesis induced by insulinlike growth factor-I in FRTL-5 cells. Endocrinology. 2000;141:2429-2438.
31. Suh JM, Song JH, Kim DW, et al. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland. J Biol Chem. 2003;278:21960-21971.
32. Ariga M, Nedachi T, Akahori M, et al. Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells. Biochem J. 2000;348:409-416.
33. Clarke JF, Young PW, Yonezawa K, Kasuga M, Holman GD. Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J. 1994;300:631-635.
34. Kanai F, Ito K, Todaka M, et al. Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase. Biochem Biophys Res Commun. 1993;195:762-768.
35. Coulonval K, Vandeput F, Stein RC, Kozma SC, Lamy F, Dumont JE. Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin. Biochem J. 2000;348:351-358.
36. Ciullo I, Diez-Roux G, Di Domenico M, Migliaccio A, Avvedimento EV. cAMP signaling selectively influences Ras effectors pathways. Oncogene. 2001;20:1186-1192.
37. Khosravi-Far R, Der CJ. The Ras signal transduction pathway. Cancer Metastasis Rev. 1994;13:67-89.
38. Gire V, Marshall C, Wynford-Thomas D. PI-3-kinase is an essential antiapoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS. Oncogene. 2000;19:2269-2276.
39. - symporter (NIS) in a large sampling of thyroid cancer cases. J Clin Endocrinol Metab. 2001;86:2697-2700.
40. - symporter (NIS) research in the thyroid and beyond. Mol Cell Endocrinol. 2003;213:59-70.