-
2
-
-
0141756175
-
Integrin avidity regulation: Are changes in affinity and conformation underemphasized?
-
Carman CV, Springer TA. Integrin avidity regulation: are changes in affinity and conformation underemphasized? Curr Opin Cell Biol 2003;15:547-556.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 547-556
-
-
Carman, C.V.1
Springer, T.A.2
-
3
-
-
0036683057
-
Role of integrins in regulating epidermal adhesion, growth and differentiation
-
Watt FM. Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J 2002;21:3919-3926.
-
(2002)
EMBO J
, vol.21
, pp. 3919-3926
-
-
Watt, F.M.1
-
4
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
Kim M, Carman CV, Springer TA. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 2003;301:1720-1725.
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
5
-
-
0033517796
-
Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on αIIbβ3 integrin conformation and oligomerization
-
Hantgan RR, Paumi C, Rocco M, Weisel JW. Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on αIIbβ3 integrin conformation and oligomerization. Biochemistry 1999;38:14461-14474.
-
(1999)
Biochemistry
, vol.38
, pp. 14461-14474
-
-
Hantgan, R.R.1
Paumi, C.2
Rocco, M.3
Weisel, J.W.4
-
7
-
-
0037195164
-
Three-dimensional model of the human platelet integrin α(IIb)β(3) based on electron cryomicroscopy and X-ray crystallography
-
Adair BD, Yeager M. Three-dimensional model of the human platelet integrin α(IIb)β(3) based on electron cryomicroscopy and X-ray crystallography. Proc Natl Acad Sci USA 2002;99:14059-14064.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14059-14064
-
-
Adair, B.D.1
Yeager, M.2
-
8
-
-
14844323604
-
Transmembrane domain helix packing stabilizes integrin αIIbβ3 in the low affinity state
-
Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. Transmembrane domain helix packing stabilizes integrin αIIbβ3 in the low affinity state. J Biol Chem 2005;280:7294-7300.
-
(2005)
J Biol Chem
, vol.280
, pp. 7294-7300
-
-
Partridge, A.W.1
Liu, S.2
Kim, S.3
Bowie, J.U.4
Ginsberg, M.H.5
-
9
-
-
16644396938
-
A specific interface between integrin transmembrane helices and affinity for ligand
-
Luo BH, Springer TA, Takagi J. A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol 2004;2:e153.
-
(2004)
PLoS Biol
, vol.2
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
10
-
-
18944403970
-
A coiled-coil structure of the αIIbβ3 integrin transmembrane and cytoplasmic domains in its resting state
-
Gottschalk KE. A coiled-coil structure of the αIIbβ3 integrin transmembrane and cytoplasmic domains in its resting state. Structure 2005;13:703-712.
-
(2005)
Structure
, vol.13
, pp. 703-712
-
-
Gottschalk, K.E.1
-
12
-
-
0037474296
-
GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane
-
Schneider D, Engelman DM. GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane. J Biol Chem 2003;278:3105-3111.
-
(2003)
J Biol Chem
, vol.278
, pp. 3105-3111
-
-
Schneider, D.1
Engelman, D.M.2
-
13
-
-
1642396353
-
Involvement of transmembrane domain interactions in signal transduction by α/β integrins
-
Schneider D, Engelman DM. Involvement of transmembrane domain interactions in signal transduction by α/β integrins. J Biol Chem 2004;279:9840-9846.
-
(2004)
J Biol Chem
, vol.279
, pp. 9840-9846
-
-
Schneider, D.1
Engelman, D.M.2
-
14
-
-
0030932407
-
A transmembrane helix dimer: Structure and implications
-
MacKenzie KR, Prestegard JH, Engelman DM. A transmembrane helix dimer: structure and implications. Science 1997;276:131-133.
-
(1997)
Science
, vol.276
, pp. 131-133
-
-
MacKenzie, K.R.1
Prestegard, J.H.2
Engelman, D.M.3
-
15
-
-
13444291852
-
A push-pull mechanism for regulating integrin function
-
Li W, Metcalf DG, Gorelik R, Li R, Mitra N, Nanda V, Law PB, Lear JD, Degrado WF, Bennett JS. A push-pull mechanism for regulating integrin function. Proc Natl Acad Sci USA 2005;102:1424-1429.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1424-1429
-
-
Li, W.1
Metcalf, D.G.2
Gorelik, R.3
Li, R.4
Mitra, N.5
Nanda, V.6
Law, P.B.7
Lear, J.D.8
Degrado, W.F.9
Bennett, J.S.10
-
16
-
-
33645020555
-
Two types of transmembrane homomeric interactions in the integrin receptor family are evolutionarily conserved
-
Lin X, Tan SM, Law SKA, Torres J. Two types of transmembrane homomeric interactions in the integrin receptor family are evolutionarily conserved. Proteins 2006;63:16-23.
-
(2006)
Proteins
, vol.63
, pp. 16-23
-
-
Lin, X.1
Tan, S.M.2
Law, S.K.A.3
Torres, J.4
-
17
-
-
0035882546
-
A new method to model membrane protein structure based on silent amino acid substitutions
-
Briggs JA, Torres J, Arkin IT. A new method to model membrane protein structure based on silent amino acid substitutions. Proteins 2001;44:370-375.
-
(2001)
Proteins
, vol.44
, pp. 370-375
-
-
Briggs, J.A.1
Torres, J.2
Arkin, I.T.3
-
18
-
-
0036111126
-
Contribution of energy values to the analysis of global searching molecular dynamics simulations of transmembrane helical bundles
-
Torres J, Briggs JA, Arkin IT. Contribution of energy values to the analysis of global searching molecular dynamics simulations of transmembrane helical bundles. Biophys J 2002;82:3063-3071.
-
(2002)
Biophys J
, vol.82
, pp. 3063-3071
-
-
Torres, J.1
Briggs, J.A.2
Arkin, I.T.3
-
19
-
-
0036289317
-
Convergence of experimental, computational and evolutionary approaches predicts the presence of a tetrameric form for CD3-ζ
-
Torres J, Briggs JA, Arkin IT. Convergence of experimental, computational and evolutionary approaches predicts the presence of a tetrameric form for CD3-ζ. J Mol Biol 2002;316:375-384.
-
(2002)
J Mol Biol
, vol.316
, pp. 375-384
-
-
Torres, J.1
Briggs, J.A.2
Arkin, I.T.3
-
21
-
-
3543012707
-
Crystallography and NMR system: A new software suite for macromolecular structure determination
-
Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL. Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Cryst D 1998;54:905-921.
-
(1998)
Acta Cryst D
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
Delano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
Read, R.J.11
Rice, L.M.12
Simonson, T.13
Warren, G.L.14
-
22
-
-
0029557910
-
Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban
-
Adams PD, Arkin IT, Engelman DM, Brunger AT. Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban. Nat Struct Biol 1995;2:154-162.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 154-162
-
-
Adams, P.D.1
Arkin, I.T.2
Engelman, D.M.3
Brunger, A.T.4
-
23
-
-
0035910270
-
Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
-
Krogh A, Larsson B, von Heijne G, Sonnhammer ELL. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 2001;305:567-580.
-
(2001)
J Mol Biol
, vol.305
, pp. 567-580
-
-
Krogh, A.1
Larsson, B.2
Von Heijne, G.3
Sonnhammer, E.L.L.4
-
24
-
-
0029966310
-
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
-
Hughes PE, Diaz-Gonzalez F, Leong L, Wu C, McDonald JA, Shattil SJ, Ginsberg MH. Breaking the integrin hinge. A defined structural constraint regulates integrin signaling. J Biol Chem 1996;271:6571-6574.
-
(1996)
J Biol Chem
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
Diaz-Gonzalez, F.2
Leong, L.3
Wu, C.4
McDonald, J.A.5
Shattil, S.J.6
Ginsberg, M.H.7
-
25
-
-
0037031551
-
A structural mechanism of integrin αIIbβ3 "inside- out" activation as regulated by its cytoplasmic face
-
Vinogradova O, Velyvis A, Velyviene A, Hu B, Haas TA, Plow EF, Qin J. A structural mechanism of integrin αIIbβ3 "inside-out" activation as regulated by its cytoplasmic face. Cell 2002;110:587-597.
-
(2002)
Cell
, vol.110
, pp. 587-597
-
-
Vinogradova, O.1
Velyvis, A.2
Velyviene, A.3
Hu, B.4
Haas, T.A.5
Plow, E.F.6
Qin, J.7
-
26
-
-
0037197990
-
Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits
-
Weljie AM, Hwang PM, Vogel HJ. Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits. Proc Natl Acad Sci USA 2002;99:5878-5883.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5878-5883
-
-
Weljie, A.M.1
Hwang, P.M.2
Vogel, H.J.3
-
27
-
-
0034652205
-
A structural basis for integrin activation by the cytoplasmic tail of the α(IIb)-subunit
-
Vinogradova O, Haas T, Plow EF, Qin J. A structural basis for integrin activation by the cytoplasmic tail of the α(IIb)-subunit. Proc Natl Acad Sci USA 2000;97:1450-1455.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1450-1455
-
-
Vinogradova, O.1
Haas, T.2
Plow, E.F.3
Qin, J.4
-
28
-
-
0032406838
-
Statistical analysis of predicted transmembrane α-helices
-
Arkin IT, Brunger AT. Statistical analysis of predicted transmembrane α-helices. Biochim Biophys Acta 1998;1429:113-128.
-
(1998)
Biochim Biophys Acta
, vol.1429
, pp. 113-128
-
-
Arkin, I.T.1
Brunger, A.T.2
-
29
-
-
0034711958
-
Statistical analysis of amino acid patterns in transmembrane helices: The GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions
-
Senes A, Gerstein M, Engelman DM. Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions. J Mol Biol 2000;296:921-936.
-
(2000)
J Mol Biol
, vol.296
, pp. 921-936
-
-
Senes, A.1
Gerstein, M.2
Engelman, D.M.3
-
30
-
-
0037136435
-
Genomic analysis of membrane protein families: Abundance and conserved motifs
-
Liu Y, Engelman DM, Gerstein M. Genomic analysis of membrane protein families: abundance and conserved motifs. Genome Biol 2002;3:1-12.
-
(2002)
Genome Biol
, vol.3
, pp. 1-12
-
-
Liu, Y.1
Engelman, D.M.2
Gerstein, M.3
-
31
-
-
0037031906
-
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
-
Takagi J, Petre BM, Walz T, Springer TA. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 2002;110:599-611.
-
(2002)
Cell
, vol.110
, pp. 599-611
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
32
-
-
2942700100
-
Dimerization of the transmembrane domain of integrin αIIb subunit in cell membranes
-
Li RH, Gorelik R, Nanda V, Law PB, Lear JD, DeGrado WF, Bennett JS. Dimerization of the transmembrane domain of integrin αIIb subunit in cell membranes. J Biol Chem 2004;279:26666-26673.
-
(2004)
J Biol Chem
, vol.279
, pp. 26666-26673
-
-
Li, R.H.1
Gorelik, R.2
Nanda, V.3
Law, P.B.4
Lear, J.D.5
Degrado, W.F.6
Bennett, J.S.7
-
33
-
-
2942587504
-
A computational model of transmembrane integrin clustering
-
Gottschalk KE, Kessler H. A computational model of transmembrane integrin clustering. Structure 2004;12:1109-1116.
-
(2004)
Structure
, vol.12
, pp. 1109-1116
-
-
Gottschalk, K.E.1
Kessler, H.2
|