메뉴 건너뛰기




Volumn 40, Issue 3-4, 1997, Pages 119-125

Azole antifungals: Weak inhibitors of inducible nitric oxide synthase in mouse and human cells

Author keywords

Azoles; Inducible nitric oxide synthase; Itraconazole; Ketoconazole; Miconazole; Nitric oxide

Indexed keywords

ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PYRROLE DERIVATIVE;

EID: 0030714670     PISSN: 09337407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1439-0507.1997.tb00200.x     Document Type: Article
Times cited : (5)

References (33)
  • 1
    • 0027516696 scopus 로고
    • Inerleukin-4 and interlukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans
    • Cenci, E., Romani, L., Mencacci, A., Spaccapelo, R., et al. (1993) Inerleukin-4 and interlukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans. Eur. J. Immunol. 23, 1034 1038.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1034-1038
    • Cenci, E.1    Romani, L.2    Mencacci, A.3    Spaccapelo, R.4
  • 2
    • 0010711735 scopus 로고
    • Specific amino acid (L-arginine) requirements for the microbiostatic activity of murine macrophages
    • Granger, D. L., Hibbs, J. B. Jr., Perfect, J. R. and Durack, D. T. (1988) Specific amino acid (L-arginine) requirements for the microbiostatic activity of murine macrophages. J. Clin. Invest. 81, 1129 1136.
    • (1988) J. Clin. Invest. , vol.81 , pp. 1129-1136
    • Granger, D.L.1    Hibbs Jr., J.B.2    Perfect, J.R.3    Durack, D.T.4
  • 3
    • 0025017079 scopus 로고
    • Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages
    • Granger, D. L., Hibbs, J. B. Jr., Perfect, J. R. and Durack, D. T. (1990) Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J. Clin. Invest. 85, 264 273.
    • (1990) J. Clin. Invest. , vol.85 , pp. 264-273
    • Granger, D.L.1    Hibbs Jr., J.B.2    Perfect, J.R.3    Durack, D.T.4
  • 4
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, and pharmacology
    • Moncada, S., Palmer, R. M. J. and Higgs, E. A. (1991) Nitric oxide: physiology, and pharmacology. Pharmacol. Rev. 43, 109 142.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 5
    • 0028125721 scopus 로고
    • The argininenitric oxide pathway: A target for new drugs
    • Kerwin, J. F. Jr. and Heller, M. (1994) The argininenitric oxide pathway: a target for new drugs. Med. Res. Rev. 14, 23 74.
    • (1994) Med. Res. Rev. , vol.14 , pp. 23-74
    • Kerwin Jr., J.F.1    Heller, M.2
  • 6
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees, D. D., Palmer, R. M. J., Schulz, R., Hodson, H. F. and Moncada, S. (1990) Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101, 746 752.
    • (1990) Br. J. Pharmacol. , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.J.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 7
    • 0027295193 scopus 로고
    • The dual mode of inhibition of calmodulin-dependent nitricoxide synthase by antifungal imidazole agents
    • Wolff, D. J., Datto, G. A. and Samatovicz, A. (1993) The dual mode of inhibition of calmodulin-dependent nitricoxide synthase by antifungal imidazole agents. J. Biol. Chem. 268, 9430 9436.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9430-9436
    • Wolff, D.J.1    Datto, G.A.2    Samatovicz, A.3
  • 8
    • 0028300099 scopus 로고
    • Effect of antifungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase
    • Bogle, R. G., Whitley, G. St. J., Soo, S.-C., Johnstone, A. P. and Vallance, P. (1994) Effect of antifungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase. Br. J. Pharmacol. 111, 1257 1261.
    • (1994) Br. J. Pharmacol. , vol.111 , pp. 1257-1261
    • Bogle, R.G.1    Whitley, G.St.J.2    Soo, S.-C.3    Johnstone, A.P.4    Vallance, P.5
  • 9
    • 0029915831 scopus 로고    scopus 로고
    • Functional effects of econazole on inducible nitric oxide synthase: Production of a calmodulin-dependent enzyme
    • Bogle, R. G. and Vallance, P. (1996) Functional effects of econazole on inducible nitric oxide synthase: production of a calmodulin-dependent enzyme. Br. J. Pharmacol. 117, 1053 1058.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1053-1058
    • Bogle, R.G.1    Vallance, P.2
  • 10
    • 0028335308 scopus 로고
    • Human monocytes/macrophages: NO or no NO?
    • Denis, M. (1994) Human monocytes/macrophages: NO or no NO? J. Leuk. Biol. 55, 682 684.
    • (1994) J. Leuk. Biol. , vol.55 , pp. 682-684
    • Denis, M.1
  • 11
    • 0028236275 scopus 로고
    • Regulation of inducible nitric oxide synthase mRNA levels by LPS, INFγ, TGF-β and IL-10 in murine macrophage cell lines and rat peritoneal macrophages
    • Chesrown, S. E., Monnier, J., Visner, G. and Nick, H. S. (1994) Regulation of inducible nitric oxide synthase mRNA levels by LPS, INFγ, TGF-β and IL-10 in murine macrophage cell lines and rat peritoneal macrophages. Biochem. Biophys. Res. Commun. 200, 126 134.
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 126-134
    • Chesrown, S.E.1    Monnier, J.2    Visner, G.3    Nick, H.S.4
  • 12
    • 0027937121 scopus 로고
    • Nitric oxide synthase: MRNA expression of different isoforms in human monocytes/macrophages
    • Reiling, N., Ulmer, A. J., Duchrow, M., Ernst, M., Flad, H-D. and Hauschildt, S. (1994) Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages. Eur. J. Immunol. 24, 1941-1944.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1941-1944
    • Reiling, N.1    Ulmer, A.J.2    Duchrow, M.3    Ernst, M.4    Flad, H.-D.5    Hauschildt, S.6
  • 13
    • 0029133539 scopus 로고
    • Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages
    • Weinberg, J. B., Misukonis, M. A., Shami, P. J. et al. (1995) Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood 86, 1184-1195.
    • (1995) Blood , vol.86 , pp. 1184-1195
    • Weinberg, J.B.1    Misukonis, M.A.2    Shami, P.J.3
  • 14
    • 0028853663 scopus 로고
    • Role of nitric oxide in parasitic infections
    • James, S. L. (1995) Role of nitric oxide in parasitic infections. Microbiol. Rev. 59, 533 547.
    • (1995) Microbiol. Rev. , vol.59 , pp. 533-547
    • James, S.L.1
  • 15
    • 0023408236 scopus 로고
    • Macrophage synthesis of nitrite, nitrate, and N-nitrosamincs: Precursors and role of respiratory burst
    • Iyengar, R., Steuhr, D. J. and Marietta, M. A. (1987) Macrophage synthesis of nitrite, nitrate, and N-nitrosamincs: precursors and role of respiratory burst. Proc. Natl Acad. Sci. USA 84, 6369 6373.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 6369-6373
    • Iyengar, R.1    Steuhr, D.J.2    Marietta, M.A.3
  • 16
    • 0026744830 scopus 로고
    • Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line
    • Lyons, C. R., Orloff, G. J. and Cunningham, J. M. (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267, 6370 6374.
    • (1992) J. Biol. Chem. , vol.267 , pp. 6370-6374
    • Lyons, C.R.1    Orloff, G.J.2    Cunningham, J.M.3
  • 17
    • 0027066985 scopus 로고
    • Regulation and subcellular location of nitrogen oxide synthases in RAW 264.7 macrophages
    • Schmidt, H. H. H. W., Warner, T. D., Nakane, M., Forstermann, U. and Murad, F. (1992) Regulation and subcellular location of nitrogen oxide synthases in RAW 264.7 macrophages. Mol. Pharmacol 41, 615 624.
    • (1992) Mol. Pharmacol , vol.41 , pp. 615-624
    • Schmidt, H.H.H.W.1    Warner, T.D.2    Nakane, M.3    Forstermann, U.4    Murad, F.5
  • 18
    • 0027372580 scopus 로고
    • Purification and cDNA sequence of an inducible nitric oxide synthase from human tumor cell line
    • Sherman, P. A., Laubach, V. E., Reep, B. R. and Wood, E. R. (1993) Purification and cDNA sequence of an inducible nitric oxide synthase from human tumor cell line. Biochemistry 32, 11600-11605.
    • (1993) Biochemistry , vol.32 , pp. 11600-11605
    • Sherman, P.A.1    Laubach, V.E.2    Reep, B.R.3    Wood, E.R.4
  • 20
    • 0027516696 scopus 로고
    • Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans
    • Cenci, E., Romani, L. and Mencacci, A. (1993) Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans. Eur. J. Immunol. 23, 1034-1038.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1034-1038
    • Cenci, E.1    Romani, L.2    Mencacci, A.3
  • 21
    • 0027447237 scopus 로고
    • Measurement of nitric oxide in biological models
    • Archer, S. (1993) Measurement of nitric oxide in biological models. FASEB J. 7, 349-360.
    • (1993) FASEB J. , vol.7 , pp. 349-360
    • Archer, S.1
  • 22
    • 0028310361 scopus 로고
    • Mesure du monooxyde d'azote et systèmes biologiques
    • Cristol, J-P., Guerin, M-C. and Torreilles, J. (1994) Mesure du monooxyde d'azote et systèmes biologiques. Life Sci. 317, 549-560.
    • (1994) Life Sci. , vol.317 , pp. 549-560
    • Cristol, J.-P.1    Guerin, M.-C.2    Torreilles, J.3
  • 23
    • 0028349156 scopus 로고
    • Nitric oxide synthases in mammals
    • Knowles, R. G. and Moncada, S. (1994) Nitric oxide synthases in mammals. Biochem. J. 298, 249 258.
    • (1994) Biochem. J. , vol.298 , pp. 249-258
    • Knowles, R.G.1    Moncada, S.2
  • 24
    • 0028836280 scopus 로고
    • Inhibition of nitric-oxide synthase potential for a novel class of therapeutic agent
    • Ogden, J. E. and Moore, P. K. (1995) Inhibition of nitric-oxide synthase potential for a novel class of therapeutic agent. Trends Biotechnol. 13, 70 78.
    • (1995) Trends Biotechnol. , vol.13 , pp. 70-78
    • Ogden, J.E.1    Moore, P.K.2
  • 25
    • 0028070186 scopus 로고
    • Kinetics of the reaction of nitric oxide with oxygen in aqueous solutions
    • Lewis, R. S. and Deen, W. M. (1994) Kinetics of the reaction of nitric oxide with oxygen in aqueous solutions. Chem. Res. Toxicol. 7, 568 574.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 568-574
    • Lewis, R.S.1    Deen, W.M.2
  • 26
    • 0026551892 scopus 로고
    • Macrophages can convert citrulline into arginine
    • Wu, G. and Brosnan, J. T. (1992) Macrophages can convert citrulline into arginine. Biochem. J. 281, 45 48.
    • (1992) Biochem. J. , vol.281 , pp. 45-48
    • Wu, G.1    Brosnan, J.T.2
  • 27
    • 0028172743 scopus 로고
    • Effects of cytokine synthesis inhibitor CGP 47969A on nitric oxide production by lipopolysaccharide- Stimulated J774A.1 macrophages
    • Hall, T. J., Gasser, J., Feige, U. and Ferrini, P. G. (1994) Effects of cytokine synthesis inhibitor CGP 47969A on nitric oxide production by lipopolysaccharide- stimulated J774A.1 macrophages. Agents Actions 43, 60-63.
    • (1994) Agents Actions , vol.43 , pp. 60-63
    • Hall, T.J.1    Gasser, J.2    Feige, U.3    Ferrini, P.G.4
  • 28
    • 0027411548 scopus 로고
    • Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide
    • Bermudez, L. E. (1993) Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages. The role of nitric oxide. Clin. Exp. Immunol. 91, 277-281.
    • (1993) Clin. Exp. Immunol. , vol.91 , pp. 277-281
    • Bermudez, L.E.1
  • 29
    • 0025687404 scopus 로고
    • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate
    • Cameron, M. L., Granger, D. L., Weinberg, J. B., Kozumbo, W. J. and Koren, H. S. (1990) Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. Am. Rev. Respir. Dis. 142, 1313 1319.
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 1313-1319
    • Cameron, M.L.1    Granger, D.L.2    Weinberg, B.J.3    Kozumbo, J.W.4    Koren, H.S.5
  • 30
    • 0027948094 scopus 로고
    • Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors
    • De Maria, R., Cifone, M. G., Trotta, R., Rippo, M. R., Festuccia, C., Santoni, A. and Testi, R. (1994) Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. J. Exp. Med. 180, 1999 2004.
    • (1994) J. Exp. Med. , vol.180 , pp. 1999-2004
    • De Maria, R.1    Cifone, M.G.2    Trotta, R.3    Rippo, M.R.4    Festuccia, C.5    Santoni, A.6    Testi, R.7
  • 31
    • 0028174192 scopus 로고
    • Involvement of FcRII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions
    • Mossalayi, M. D., Paul-eugene, N. and Quaaz, F. (1994) Involvement of FcRII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions. Int. Immunol. 7, 931 934.
    • (1994) Int. Immunol. , vol.7 , pp. 931-934
    • Mossalayi, M.D.1    Paul-eugene, N.2    Quaaz, F.3
  • 32
    • 0028010766 scopus 로고
    • Gp 120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages
    • Pietraforte, D., Tritarelli, E., Testa, U. and Minetti, M. (1994) Gp 120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages. J. Leukocyte Biol. 55, 175 182.
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 175-182
    • Pietraforte, D.1    Tritarelli, E.2    Testa, U.3    Minetti, M.4
  • 33
    • 0004329410 scopus 로고
    • The molecular basis for the antifungal activities of N-substituted azole derivatives. Focus on R 51211
    • Trinci, A. P. J. and Ryley, J. F. (eds) UK: British
    • Vanden Bossche, H., Willemsens, G., Marichal, P., Cools, W. and Lauwers, W. (1984) The molecular basis for the antifungal activities of N-substituted azole derivatives. Focus on R 51211. In: Trinci, A. P. J. and Ryley, J. F. (eds) Mode of Action of Antifungal Agents. UK: British
    • (1984) Mode of Action of Antifungal Agents
    • Vanden Bossche, H.1    Willemsens, G.2    Marichal, P.3    Cools, W.4    Lauwers, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.