메뉴 건너뛰기




Volumn 21, Issue 6, 2006, Pages 1564-1575

Human testis in organotypic culture: Application for basic or clinical research

Author keywords

Human; Organotypic culture; Testis

Indexed keywords

BROXURIDINE; CELL MARKER; GONADOTROPIN;

EID: 33749004505     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del018     Document Type: Article
Times cited : (71)

References (56)
  • 2
  • 3
    • 0002578096 scopus 로고
    • Quelsques résultats de la méthode de culture des tissus
    • Champy C (1920) Quelsques résultats de la méthode de culture des tissus. Arch Zool Exp Gen 60,461-500.
    • (1920) Arch Zool Exp Gen , vol.60 , pp. 461-500
    • Champy, C.1
  • 4
    • 0036227563 scopus 로고    scopus 로고
    • Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro
    • Chen H, Hardy MP and Zirkin BR (2002) Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro. Endocrinology 143,1637-1642.
    • (2002) Endocrinology , vol.143 , pp. 1637-1642
    • Chen, H.1    Hardy, M.P.2    Zirkin, B.R.3
  • 5
    • 4644300593 scopus 로고    scopus 로고
    • Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells
    • Chen H, Liu J, Luo L and Zirkin BR (2004) Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells. Endocrinology 145,4441-4446.
    • (2004) Endocrinology , vol.145 , pp. 4441-4446
    • Chen, H.1    Liu, J.2    Luo, L.3    Zirkin, B.R.4
  • 6
    • 75449141332 scopus 로고
    • The cycle of the seminiferous epithelium in man
    • Clermont Y (1963) The cycle of the seminiferous epithelium in man. Am J Anat 112,35-51.
    • (1963) Am J Anat , vol.112 , pp. 35-51
    • Clermont, Y.1
  • 7
    • 0032951443 scopus 로고    scopus 로고
    • In vitro maturation of round spermatids using co-culture on vero cells
    • Cremades N, Bernabeu R, Barros A and Sousa M (1999) In vitro maturation of round spermatids using co-culture on vero cells. Hum Reprod 14,1287-1293.
    • (1999) Hum Reprod , vol.14 , pp. 1287-1293
    • Cremades, N.1    Bernabeu, R.2    Barros, A.3    Sousa, M.4
  • 8
    • 0034809048 scopus 로고    scopus 로고
    • Developmental potential of elongating and elongated spermatids obtained after in-vitro maturation of isolated round spermatids
    • Cremades N, Sousa M, Bernabeu R and Barros A (2001) Developmental potential of elongating and elongated spermatids obtained after in-vitro maturation of isolated round spermatids. Hum Reprod 16,1938-1944.
    • (2001) Hum Reprod , vol.16 , pp. 1938-1944
    • Cremades, N.1    Sousa, M.2    Bernabeu, R.3    Barros, A.4
  • 10
    • 0023858837 scopus 로고
    • Endocrine regulation and communicating functions of the Leydig cell
    • Dufau ML (1988) Endocrine regulation and communicating functions of the Leydig cell. Annu Rev Physiol 50,483-508.
    • (1988) Annu Rev Physiol , vol.50 , pp. 483-508
    • Dufau, M.L.1
  • 12
    • 0023449886 scopus 로고
    • Identification of tissue histiocytes on paraffin sections by a new monoclonal antibody
    • Flavell DJ, Jones DB and Wright DH (1987) Identification of tissue histiocytes on paraffin sections by a new monoclonal antibody. J Histochem Cytochem 35,1217-1226.
    • (1987) J Histochem Cytochem , vol.35 , pp. 1217-1226
    • Flavell, D.J.1    Jones, D.B.2    Wright, D.H.3
  • 13
    • 0026740931 scopus 로고
    • Lipopolysaccharide, latex beads and residual bodies are potent activators of Sertoli cell interleukin-1 alpha production
    • Gerard N, Syed V and Jegou B (1992) Lipopolysaccharide, latex beads and residual bodies are potent activators of Sertoli cell interleukin-1 alpha production. Biochem Biophys Res Commun 185,154-161.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 154-161
    • Gerard, N.1    Syed, V.2    Jegou, B.3
  • 16
    • 0022641578 scopus 로고
    • Multinucleated spermatocytes and spermatids in human seminiferous tubules
    • Holstein AF and Eckmann C (1986) Multinucleated spermatocytes and spermatids in human seminiferous tubules. Andrologia 18,5-16.
    • (1986) Andrologia , vol.18 , pp. 5-16
    • Holstein, A.F.1    Eckmann, C.2
  • 18
    • 0031160524 scopus 로고    scopus 로고
    • Relaxin-like factor: A highly specific and constitutive new marker for Leydig cells in the human testis
    • Ivell R, Balvers M, Domagalski R, Ungefroren H, Hunt N and Schulze W (1997) Relaxin-like factor: A highly specific and constitutive new marker for Leydig cells in the human testis. Mol Hum Reprod 3,459-466.
    • (1997) Mol Hum Reprod , vol.3 , pp. 459-466
    • Ivell, R.1    Balvers, M.2    Domagalski, R.3    Ungefroren, H.4    Hunt, N.5    Schulze, W.6
  • 19
    • 7844251528 scopus 로고    scopus 로고
    • Microinjections = Macroproblems: The viewpoint of a reproductive biologist
    • Jégou B (1998) Microinjections = macroproblems: The viewpoint of a reproductive biologist. Int J Androl 21,253-255.
    • (1998) Int J Androl , vol.21 , pp. 253-255
    • Jégou, B.1
  • 21
    • 17344376208 scopus 로고
    • Evaluation of the human testis and its age-related dysfunction
    • discussion 61-67
    • Johnson L (1989) Evaluation of the human testis and its age-related dysfunction. Prog Clin Biol Res 302,35-60; discussion 61-67.
    • (1989) Prog Clin Biol Res , vol.302 , pp. 35-60
    • Johnson, L.1
  • 22
    • 0032868364 scopus 로고    scopus 로고
    • A comparative morphological study of human germ cells in vitro or in situ within seminiferous tubules
    • Johnson L, Neaves WB, Barnard JJ, Keillor GE, Brown SW and Yanagimachi R (1999) A comparative morphological study of human germ cells in vitro or in situ within seminiferous tubules. Biol Reprod 61,927-934.
    • (1999) Biol Reprod , vol.61 , pp. 927-934
    • Johnson, L.1    Neaves, W.B.2    Barnard, J.J.3    Keillor, G.E.4    Brown, S.W.5    Yanagimachi, R.6
  • 23
    • 0028118802 scopus 로고
    • Mammalian spermatogenesis in vivo and in vitro: A partnership of spermatogenic and somatic cell lineages
    • Kierszenbaum AL (1994) Mammalian spermatogenesis in vivo and in vitro: A partnership of spermatogenic and somatic cell lineages. Endocr Rev 15,116-134.
    • (1994) Endocr Rev , vol.15 , pp. 116-134
    • Kierszenbaum, A.L.1
  • 24
    • 0028223692 scopus 로고
    • Structure, regulation and role of 3 beta-hydroxysteroid dehydrogenase, 17 beta-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues
    • Labrie F, Simard J, Luu-The V, Pelletier G, Belghmi K and Belanger A (1994) Structure, regulation and role of 3 beta-hydroxysteroid dehydrogenase, 17 beta-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues. Baillieres Clin Endocrinol Metab 8,451-474.
    • (1994) Baillieres Clin Endocrinol Metab , vol.8 , pp. 451-474
    • Labrie, F.1    Simard, J.2    Luu-The, V.3    Pelletier, G.4    Belghmi, K.5    Belanger, A.6
  • 25
    • 0023906332 scopus 로고
    • In vitro effects of germ cells on the secretory activity of Sertoli cells recovered from rats of different ages
    • Le Magueresse B and Jégou B (1988) In vitro effects of germ cells on the secretory activity of Sertoli cells recovered from rats of different ages. Endocrinology 122,1672-1680.
    • (1988) Endocrinology , vol.122 , pp. 1672-1680
    • Le Magueresse, B.1    Jégou, B.2
  • 26
    • 0022534117 scopus 로고
    • Stimulation of rat Sertoli cell secretory activity in vitro by germ cells and residual bodies
    • Le Magueresse B, Le Gac F, Loir M and Jégou B (1986) Stimulation of rat Sertoli cell secretory activity in vitro by germ cells and residual bodies. J Reprod Fertil 77,489-498.
    • (1986) J Reprod Fertil , vol.77 , pp. 489-498
    • Le Magueresse, B.1    Le Gac, F.2    Loir, M.3    Jégou, B.4
  • 28
    • 7344251712 scopus 로고    scopus 로고
    • Expression of DAZ (deleted in azoospermia), DAZL1 (DAZ-like) and protamine-2 in testis and its application for diagnosis of spermatogenesis in non-obstructive azoospermia
    • Lee JH, Lee DR, Yoon SJ, Chai YG, Roh SI and Yoon HS (1998) Expression of DAZ (deleted in azoospermia), DAZL1 (DAZ-like) and protamine-2 in testis and its application for diagnosis of spermatogenesis in non-obstructive azoospermia. Mol Hum Reprod 4,827-834.
    • (1998) Mol Hum Reprod , vol.4 , pp. 827-834
    • Lee, J.H.1    Lee, D.R.2    Yoon, S.J.3    Chai, Y.G.4    Roh, S.I.5    Yoon, H.S.6
  • 30
    • 0031037973 scopus 로고    scopus 로고
    • Expression of DAZ, an azoospermia factor candidate, in human spermatogonia
    • Menke DB, Mutter GL and Page DC (1997) Expression of DAZ, an azoospermia factor candidate, in human spermatogonia. Am J Hum Genet 60,237-241.
    • (1997) Am J Hum Genet , vol.60 , pp. 237-241
    • Menke, D.B.1    Mutter, G.L.2    Page, D.C.3
  • 31
    • 3242698031 scopus 로고    scopus 로고
    • Expression and function of class B scavenger receptor type I on both apical and basolateral sides of the plasma membrane of polarized testicular Sertoli cells of the rat
    • Nakagawa A, Nagaosa K, Hirose T, Tsuda K, Hasegawa K, Shiratsuchi A and Nakanishi Y (2004) Expression and function of class B scavenger receptor type I on both apical and basolateral sides of the plasma membrane of polarized testicular Sertoli cells of the rat. Dev Growth Differ 46,283-298.
    • (2004) Dev Growth Differ , vol.46 , pp. 283-298
    • Nakagawa, A.1    Nagaosa, K.2    Hirose, T.3    Tsuda, K.4    Hasegawa, K.5    Shiratsuchi, A.6    Nakanishi, Y.7
  • 35
    • 0344813043 scopus 로고
    • Testicular temperature in man
    • Newman HF and Wilhelm SF (1950) Testicular temperature in man. J Urol 63,349-352.
    • (1950) J Urol , vol.63 , pp. 349-352
    • Newman, H.F.1    Wilhelm, S.F.2
  • 38
    • 0037401968 scopus 로고    scopus 로고
    • Development of the meiotic step in testes of pubertal rats: Comparison between the in vivo situation and under in vitro conditions
    • Perrard MH, Hue D, Staub C, Le Vern Y, Kerboeuf D and Durand P (2003) Development of the meiotic step in testes of pubertal rats: Comparison between the in vivo situation and under in vitro conditions. Mol Reprod Dev 65,86-95.
    • (2003) Mol Reprod Dev , vol.65 , pp. 86-95
    • Perrard, M.H.1    Hue, D.2    Staub, C.3    Le Vern, Y.4    Kerboeuf, D.5    Durand, P.6
  • 39
    • 0025359027 scopus 로고
    • Regulation of Sertoli cell inhibin production and of inhibin subunit mRNA levels by specific germ cell types
    • Pineau C, Sharpe RM, Saunders P, Gérard N and Jégou B (1990) Regulation of Sertoli cell inhibin production and of inhibin subunit mRNA levels by specific germ cell types. Mol Cell Endocrinol 72,13-22.
    • (1990) Mol Cell Endocrinol , vol.72 , pp. 13-22
    • Pineau, C.1    Sharpe, R.M.2    Saunders, P.3    Gérard, N.4    Jégou, B.5
  • 41
    • 0038346008 scopus 로고    scopus 로고
    • Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood
    • Sharpe RM, McKinnell C, Kivlin C and Fisher JS (2003) Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction 125,769-784.
    • (2003) Reproduction , vol.125 , pp. 769-784
    • Sharpe, R.M.1    McKinnell, C.2    Kivlin, C.3    Fisher, J.S.4
  • 42
    • 20844437756 scopus 로고    scopus 로고
    • Efforts to create an artificial testis: Culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment
    • (Epub 7 April 2005)
    • Sofikitis N, Pappas E, Kawatani A, Baltogiannis D, Loutradis D, Kanakas N, Giannakis D, Dimitriadis F, Tsoukanelis K, Georgiou I et al. (2005) Efforts to create an artificial testis: Culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment. Hum Reprod Update 11,229-259 (Epub 7 April 2005).
    • (2005) Hum Reprod Update , vol.11 , pp. 229-259
    • Sofikitis, N.1    Pappas, E.2    Kawatani, A.3    Baltogiannis, D.4    Loutradis, D.5    Kanakas, N.6    Giannakis, D.7    Dimitriadis, F.8    Tsoukanelis, K.9    Georgiou, I.10
  • 43
    • 0343238412 scopus 로고    scopus 로고
    • Expression pattern of germ cell-specific genes in the testis of patients with nonobstructive azoospermia: Usefulness as a molecular marker to predict the presence of testicular sperm
    • Song GJ, Lee H, Park Y, Lee HJ, Lee YS, Seo JT and Kang IS (2000) Expression pattern of germ cell-specific genes in the testis of patients with nonobstructive azoospermia: Usefulness as a molecular marker to predict the presence of testicular sperm. Fertil Steril 73,1104-1108.
    • (2000) Fertil Steril , vol.73 , pp. 1104-1108
    • Song, G.J.1    Lee, H.2    Park, Y.3    Lee, H.J.4    Lee, Y.S.5    Seo, J.T.6    Kang, I.S.7
  • 44
    • 0036161226 scopus 로고    scopus 로고
    • Developmental potential of human spermatogenic cells co-cultured with Sertoli cells
    • Sousa M, Cremades N, Alves C, Silva J and Barros A (2002) Developmental potential of human spermatogenic cells co-cultured with Sertoli cells. Hum Reprod 17,161-172.
    • (2002) Hum Reprod , vol.17 , pp. 161-172
    • Sousa, M.1    Cremades, N.2    Alves, C.3    Silva, J.4    Barros, A.5
  • 45
    • 0034749713 scopus 로고    scopus 로고
    • A century of research on mammalian male germ cell meiotic differentiation in vitro
    • Staub C (2001) A century of research on mammalian male germ cell meiotic differentiation in vitro. J Androl 22,911-926.
    • (2001) J Androl , vol.22 , pp. 911-926
    • Staub, C.1
  • 46
    • 0002592899 scopus 로고
    • Maintenance of adult human testicular tissue in culture
    • Steinberger E (1967) Maintenance of adult human testicular tissue in culture. Anat Rec 157,327-328.
    • (1967) Anat Rec , vol.157 , pp. 327-328
    • Steinberger, E.1
  • 47
    • 0016412969 scopus 로고
    • In vitro techniques for the study of spermatogenesis
    • Steinberger A (1975) In vitro techniques for the study of spermatogenesis. Methods Enzymol 39,283-296.
    • (1975) Methods Enzymol , vol.39 , pp. 283-296
    • Steinberger, A.1
  • 48
    • 0001532291 scopus 로고
    • Some observations on the effect of heat on the testicular germinal epithelium
    • Steinberger E and Dixon WJ (1959) Some observations on the effect of heat on the testicular germinal epithelium. Fertil Steril 10,578-595.
    • (1959) Fertil Steril , vol.10 , pp. 578-595
    • Steinberger, E.1    Dixon, W.J.2
  • 49
    • 0000008656 scopus 로고
    • Factors affecting spermatogenesis in organ cultures of mammalian testes
    • Steinberger A and Steinberger E (1967) Factors affecting spermatogenesis in organ cultures of mammalian testes. J Reprod Fert Suppl 2,117-124.
    • (1967) J Reprod Fert Suppl , vol.2 , pp. 117-124
    • Steinberger, A.1    Steinberger, E.2
  • 50
    • 0029060690 scopus 로고
    • Residual bodies activate Sertoli cell EL-1 alpha release which triggers IL-6 production by an autocrine mechanism, through the lipoxygenase pathway
    • Syed V, Stéphan JP, Gérard N, Legrand A, Parvinen M, Bardin CW and Jégou B (1995) Residual bodies activate Sertoli cell EL-1 alpha release which triggers IL-6 production by an autocrine mechanism, through the lipoxygenase pathway. Endocrinology 136,3070-3078.
    • (1995) Endocrinology , vol.136 , pp. 3070-3078
    • Syed, V.1    Stéphan, J.P.2    Gérard, N.3    Legrand, A.4    Parvinen, M.5    Bardin, C.W.6    Jégou, B.7
  • 51
    • 0037374590 scopus 로고    scopus 로고
    • Completion of meiosis in human primary spermatocytes through in vitro coculture with Vero cells
    • Tanaka A, Nagayoshi M, Awata S, Mawatari Y, Tanaka I and Kusunoki H (2003) Completion of meiosis in human primary spermatocytes through in vitro coculture with Vero cells. Fertil Steril 79,795-801.
    • (2003) Fertil Steril , vol.79 , pp. 795-801
    • Tanaka, A.1    Nagayoshi, M.2    Awata, S.3    Mawatari, Y.4    Tanaka, I.5    Kusunoki, H.6
  • 52
    • 0031728071 scopus 로고    scopus 로고
    • Differentiation of spermatogenic cells during in-vitro culture of testicular biopsy samples from patients with obstructive azoospermia: Effect of recombinant follicle stimulating hormone
    • Tesarik J, Greco E, Rienzi L, Ubaldi F, Guido M, Cohen-Bacrie P and Mendoza C (1998a) Differentiation of spermatogenic cells during in-vitro culture of testicular biopsy samples from patients with obstructive azoospermia: Effect of recombinant follicle stimulating hormone. Hum Reprod 13,2772-2781.
    • (1998) Hum Reprod , vol.13 , pp. 2772-2781
    • Tesarik, J.1    Greco, E.2    Rienzi, L.3    Ubaldi, F.4    Guido, M.5    Cohen-Bacrie, P.6    Mendoza, C.7
  • 53
    • 0032466638 scopus 로고    scopus 로고
    • Human spermatogenesis in vitro: Respective effects of follicle-stimulating hormone and testosterone on meiosis, spermiogenesis, and Sertoli cell apoptosis
    • Tesarik J, Guido M, Mendoza C and Greco E (1998b) Human spermatogenesis in vitro: Respective effects of follicle-stimulating hormone and testosterone on meiosis, spermiogenesis, and Sertoli cell apoptosis. J Clin Endocrinol Metab 83,4467-4473.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4467-4473
    • Tesarik, J.1    Guido, M.2    Mendoza, C.3    Greco, E.4
  • 54
    • 0036153101 scopus 로고    scopus 로고
    • Pharmacological concentrations of follicle-stimulating hormone and testosterone improve the efficacy of in vitro germ cell differentiation in men with maturation arrest
    • Tesarik J, Nagy P, Abdelmassih R, Greco E and Mendoza C (2002) Pharmacological concentrations of follicle-stimulating hormone and testosterone improve the efficacy of in vitro germ cell differentiation in men with maturation arrest. Fertil Steril 77,245-251.
    • (2002) Fertil Steril , vol.77 , pp. 245-251
    • Tesarik, J.1    Nagy, P.2    Abdelmassih, R.3    Greco, E.4    Mendoza, C.5
  • 55
    • 0033796721 scopus 로고    scopus 로고
    • Regulation of Leydig cell steroidogenic function during aging
    • Zirkin BR and Chen H (2000) Regulation of Leydig cell steroidogenic function during aging. Biol Reprod 63,977-981.
    • (2000) Biol Reprod , vol.63 , pp. 977-981
    • Zirkin, B.R.1    Chen, H.2
  • 56
    • 0018324996 scopus 로고
    • Infrared thermometry for testicular temperature determinations
    • Zorgniotti AW, Toth A and McLeod J (1979) Infrared thermometry for testicular temperature determinations. Fertil Steril 32,347.
    • (1979) Fertil Steril , vol.32 , pp. 347
    • Zorgniotti, A.W.1    Toth, A.2    McLeod, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.