Molecular dynamics study of the stabilities of consensus designed ankyrin repeat proteins

Proteins: Structure, Function and Genetics

Volumn 65, Issue 2, 2006, Pages 285-295

  Yu, Haibo ^a,c   Kohl, Andreas ^b,d   Binz, H Kaspar ^b   Plückthun, Andreas ^b   Grütter, Markus G ^b   Van Gunsteren, Wilfred F ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Ankyrin repeat; Continuum electrostatics; Homology modeling; Molecular dynamics; Poisson Boltzmann; Protein design; Stability

Indexed keywords

ANKYRIN; GUANIDINE; SOLVENT;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; CONTINUUM ELECTROSTATIC MODEL; CRYSTAL STRUCTURE; DIPOLE; ELECTRICITY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUTATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SEQUENCE HOMOLOGY; SIMULATION;

ANKYRIN REPEAT; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS;

EID: 33749002845     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.20991     Document Type: Article

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