Gene expression analysis in a canine model of X-linked Alport syndrome

Mammalian Genome

Volumn 17, Issue 9, 2006, Pages 976-990

  Greer, Kimberly A ^a   Higgins, Marnie A ^b   Cox, Melissa L ^a   Ryan, Timothy P ^b   Berridge, Brian R ^b   Kashtan, Clifford E ^c   Lees, George E ^a   Murphy, Keith E ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CLUSTERIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ACO1 GENE; ALPORT SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUSE OF DEATH; CHRONIC KIDNEY DISEASE; CLU GENE; COL4A1 GENE; CONTROLLED STUDY; DOG DISEASE; EXTRACELLULAR MATRIX; FDXR GENE; FEMALE; GENE; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; GENETIC ANALYSIS; GPX1 GENE; IMMUNOPATHOLOGY; INFLAMMATION; KIDNEY CORTEX; KIDNEY FAILURE; KIDNEY FIBROSIS; KIDNEY INJURY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; METABOLIC DISORDER; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOD1 GENE; STATISTICAL ANALYSIS; TIMP 1 GENE; X CHROMOSOME LINKED DISORDER;

ANIMALS; COLLAGEN; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INFLAMMATION; KIDNEY; MALE; NEPHRITIS, HEREDITARY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA; CANIS FAMILIARIS;

EID: 33748969161     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-005-0179-8     Document Type: Article

References (47)

1. Baker TK, Higgins MA, Carfagna MA, Ryan TP (2003) Characterization of hepatocytes and their use as a model system in toxicogenomics. In: An Introduction to Toxicogenomics, Burczynski ME, (ed.) (Boca Raton, FL: CRC Press), pp 117-143
2. Baker KE, Parker R (2004) Nonsense-mediated mRNA decay; terminating erroneous gene expression. Curr Opin Cell Biol 16, 293-299
3. Basile DP, Martin DR, Hammerman MH (1998) Extracellular matrix related genes in kidney post-ischemic injury: potential role for TGF-B in repair. Am J Physiol Renal Physiol 275, F894-F903
4. Basile DP, Donohoe D, Roethe K, Osborn J (2001) Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol 281, F887-F899
5. Basile D, Fredrich K, Weihrauch DW, Hattan N, Chilian WM (2004) Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. Am J Physiol Renal Physiol 286, F893-F902
6. Basile DP, Fredrich K, Alausa M, Vio CP, Liang M, et al. (2005) Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure. Am J Physiol Renal Physiol 288, F953-F963
7. Bernard MA, Valli VE (1977) Familial renal disease in Samoyed dogs. Can Vet J 18, 181-189
8. Branton MH, Kopp JB (1999) TGF-beta and fibrosis. Microbes Infect 1, 1349-1365
9. Cox ML, Lees GE, Kashtan CE, Murphy KE (2003) Genetic cause of X-linked Alport syndrome in a family of domestic dogs. Mamm Genome 14, 396-403
10. Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2, 161-174
11. Gene Ontology Consortium (2000) Gene Ontology: tool for the unification of biology. Nat Genet 25, 25-29
12. Gross O, Netzer KO, Lambrecht R, Seibold S, Weber M (2002) Meta-analysis of genotype-phrnotype correlation in X-linked Alport syndrome: impact on clinical counseling. Nephrol Dial Transplant 17, 1218-1227
13. Hara I, Miyake H, Gleaye ME, Kamidono S (2001) Introduction of clusterin gene into human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy through inhibition of apoptosis both in vitro and in vivo. Jpn J Cancer Res 92, 1220-1224
14. Harendza S, Schneider A, Helmchen U, Stahl RA (1999) Extracellular matrix deposition and cell proliferation in a model of chronic glomerulonephritis in the rat. Nephrol Dial Transplant 14, 2873-2879
15. Higgins MA, Berridge BR, Mills BJ, Schultze AE, Gao H, et al. (2003) Gene expression analysis of the acute phase response using a canine microarray. Toxicol Sci 74, 470-484
16. Huijun W, Long C, Zhigang Z, Feng J, Muyi G (2005) Ex vivo transfer of the decorin gene into rat glomerulus via a mesangial cell vector suppressed extracellular matrix accumulation in experimental glomerulonephritis. Exp Mol Pathol 78, 17-24
17. Humes HD (1995) Acute renal failure: prevailing challenges and prospects for the future. Kidney Int Suppl 50, S26-S32
18. Isaka Y, Akagi Y, Ando Y, Tsujie M, Imai E (1999) Cytokines and glomerulosclerosis. Nephrol Dial Transplant 14 Suppl 1, 30-32
19. Kashtan CE (1998) Alport syndrome and thin glomerular basement membrane disease. J Am Soc Nephrol 9, 1736-1750
20. Kashtan CE (2002) Animal models of Alport Syndrome. Nephrol Dial Transplant 17, 1359-1361
21. Kim JY, Suh KS (1995) Light microscopic and electron microscopic features of cyclosporine nephrotoxicity in rats. J Korean Med Sci 10, 352-359
22. Kleinman JG, Worcester EM, Beshensky AM, Sheridan AM, Bonventre JV, et al. (1995) Upregulation of osteopontin expression by ischemia in rat kidney. Ann NY Acad Sci 760, 321-323
23. Klipper-Aurbach Y, Wasserman M, Braunspiegel-Weintrob N, Borstein D, Peleg S, et al. (1995) Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus. Med Hypotheses 45, 486-490
24. Lees GE, Helman RG, Kashtan CE, Michael AF, Homco LD, et al. (1999) New form of X-linked dominant hereditary nephritis in dogs. Am J Vet Res 60, 373-383
25. Matsuda A, Itoh Y, Koshikawa N, Akizawa T, Yana I, et al. (2003) Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils. J Biol Chem 278, 36350-36357
26. Murphy BF, Kirszbaum L, Walker ID, D'Apice AJ (1988) SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest 81, 1858-1864
27. Nakanishi K, Yoskikawa N, Iijima K, Nakamura H (1996) Expression of type IV collagen α3 and α4 chain mRNA in X-linked Alport syndrome. J Am Soc Nephrol 7, 938-945
28. Noiri E, Dickman K, Miller F, Romanov G, Romanov VI, et al. (1999) Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. Kidney Int 56, 74-82
29. Padanilam BJ, Martin DR, Hammerman MR (1996) Insulin-like growth factor I-enhanced renal expression of osteopontin after acute ischemic injury in rats. Endocrinology 137, 2133-2140
30. Pennie WD (2000) Use of cDNA microarrays to probe and understand the toxicological consequences of altered gene expression. Toxicol Lett 112-113, 473-477
31. Persy VP, Verhulst A, Ysebaert DK, De Greef KE, De Broe ME (2003) Reduced postischemic macrophage infiltration and interstitial fibrosis in osteopontin knockout mice. Kidney Int 63, 543-553
32. Rao VH, Lees GE, Kashtan CE, Nemori R, Singh RK, et al. (2003) Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS). Kidney Int 63, 1736-1748
33. Rao VH, Lees GE, Kashtan CE, Delimont DC, Singh R, et al. (2005) Dysregulation of renal MMP-3 and MMP-7 in canine X-linked Alport syndrome. Pediatr Nephrol 20, 732-739
34. Rheault MN, Kren SM, Thielen BK, Mesa HA, Crosson JT, et al. (2004) J Am Soc Nephrol 15, 1466-1474
35. Rosenberg ME, Girton R, Finkel D, Chmielewski D, Barrie A, et al. (2002) Apolipoprotein J/clusterin prevents a progressive glomerulopathy of aging. Mol Cell Biol 22, 1893-1902
36. Sampson NS, Ryan ST, Enke DA, Cosgrove D, Koteliansky V, et al. (2001) Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis. J Biol Chem 276, 34182-34188
37. Saunders JR, Aminian A, McRae JL, O'Farrell KA, Adam WR, et al. (1994) Clusterin depletion enhances immune glomerular injury in the isolated perfused kidney. Kidney Int 45, 817-827
38. Schnaper HW, Kopp JB, Poncelet AC, Hubchak SC, Stetler-Stevenson WG, et al. (1996) Increased expression of extracellular matrix proteins and decreased expression of matrix proteases after serial passage of glomerular mesangial cells. J Cell Sci 109, 2521-2528
39. Schwochau GB, Nath KA, Rosenberg ME (1998) Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties. Kidney Int 53, 1647-1653
40. Shinoura N, Heffelfinger SC, Miller M, Shamraj OI, Miura NH, et al. (1994) RNA expression of complement regulatory proteins in human brain tumors. Cancer Lett 86, 143-149
41. Thorner PS, Zheng K, Kalluri R, Jacobs R, Hudson BG (1996) Coordinate gene expression of the α3, α4, and α5 chains of collagen type IV: evidence from a canine model of X-linked neprhitis with a COL4A5 mutation. J Biol Chem 271, 13821-13828
42. Uchio K, Manabe N, Tamura K, Miyamoto M, Yamaguchi M, et al. (2000) Decreased matrix metalloproteinase activity in the kidneys of hereditary nephritic mice (ICGN strain). Nephron 86, 145-151
43. Vogel KG, Paulsson M, Heinegard D (1984) Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon. Biochem J 223, 587-597
44. Weber IT, Harrison RW, Iozzo RV (1996) Model structure of decorin and implications for collagen fibrillogenesis. J Biol Chem 271, 31767-31770
45. Winnemoller M, Schmidt G, Kresse H (1991) Influence of decorin on fibroblast adhesion to fibronectin. Eur J Cell Biol 45, 10-17
46. Yamada Y, Ichihara S, Izawa H, Tanaka M, Yokota M (2001) Association of a G994 → T (Val279 → Phe) polymorphism of the plasma platelet-activating factor acetylhydrolase gene with myocardial damage in Japanese patients with nonfamilial hypertrophic cardiomyopathy. J Hum Genet 46, 436-441
47. Zheng K, Thorner PS, Marrano P, Beumal R, McInnes R (1994) Canine X chromosome-linked hereditary nephritis: a genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding the alpha 5 chain of collagen type IV. Proc Natl Acad Sci USA 91, 3989-3993