Chronic morphine exposure causes pronounced virus replication in cerebral compartment and accelerated onset of AIDS in SIV/SHIV-infected Indian rhesus macaques

Virology

Volumn 354, Issue 1, 2006, Pages 192-206

  Kumar, Rakesh ^a   Orsoni, Suheydi ^a   Norman, Lisa ^a   Verma, Ashish S ^a   Tirado, Grissell ^a   Giavedoni, Luis D ^b   Staprans, Silvija ^c   Miller, Gregory M ^d   Buch, Shilpa J ^e   Kumar, Anil ^a,f  

^a Department of Microbiology   (Puerto Rico)

^b SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^f UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

AIDS; Indian rhesus macaques; Morphine; SHIV; SIV

Indexed keywords

MORPHINE; NEUTRALIZING ANTIBODY;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CELL LOSS; CELLULAR IMMUNITY; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG EXPOSURE; EUTHANASIA; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; INOCULATION; MACACA; MALE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD; VIRUS REPLICATION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ANTIBODIES, VIRAL; CD4 LYMPHOCYTE COUNT; CD4-CD8 RATIO; CEREBROSPINAL FLUID; DISEASE MODELS, ANIMAL; IMMUNITY, CELLULAR; MACACA MULATTA; MALE; MORPHINE; RNA, VIRAL; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; TELENCEPHALON; VIRAL LOAD; VIRUS REPLICATION;

ANIMALIA; MACACA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 33748965174     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.06.020     Document Type: Article

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